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The measurement of ensemble variability in time-aligned event signals is studied in relation to sampling rate requirements. The theoretical analysis is based on statistical modelling of time misalignment in which the time resolution is limited by the length of the sampling interval. For different signal-to-noise ratios (SNRs), the sampling rate is derived which limits the misalignment effect to le
Using two-pulse photon echo excitation a strong resonance in the measured homogeneous dephasing time as a function of magnetic field is observed in the H-3(4)-D-1(2) transition of Pr3+:YAlO3. The resonance could only be observed at low excitation energies since it otherwise was masked by excitation intensity dependent extra dephasing processes in the crystal. Thus intensity dependent dephasing pro
In this work, we model the basic mechanisms of the interaction between phase-transformations and plasticity within a one-dimensional constitutive framework. Efficient algorithms are presented, facilitating to solve the underlying evolution equations with high numerical stability at low numerical costs. Furthermore, a family of functions covering physically reasonable classes for the inheritance of
The use of test-coverage measures (e.g., block-coverage to control the software test process has become an increasingly common practice. This is justified by the assumption that higher test-coverage helps achieve higher defect-coverage and therefore improves software quality. In practice, data often show that defect-coverage and test-coverage grow over time, as additional testing is performed. How
The first subject addressed in this thesis is the contribution of the VSAT luminosity to the lineshape analysis, i.e. to the extraction of the mass and width of the Z0 boson from LEP1 DELPHI data. The VSAT detector has contributed to the lineshape parameter determination by providing a relative luminosity measurement of high accuracy. The second subject of the thesis is the extraction of the helic
Construction in rock is associated with risks because knowledge of the geology and ground conditions is limited. Unforeseen rock conditions involve a large risk to the project and can in the end entail delays and extra costs. To minimize the risks, an optimized pre-investigation program has to be conducted where essential information is gathered in order to make the best decisions throughout the c
Tyr-762 is an autophosphorylation site in the human platelet-derived growth factor (PDGF) alpha-receptor. In order to investigate whether phosphorylated Tyr-762 serves as a docking site for downstream signal transduction molecules, affinity purification using an immobilized synthetic peptide containing phosphorylated Tyr-762 and its surrounding amino acid residues was performed. Proteins in HeLa c
Background. To characterize participant reasons for withdrawing from a diabetes focused longitudinal clinical observational trial (TEDDY) during the first three study years. Methods. 8677 children were recruited into the TEDDY study. At participant withdrawal staff recorded any reason parents provided for withdrawal. Reasons were categorized into (1) family characteristics and (2) protocol reasons
POU5F1 has two alternatively spliced transcripts: a long (variant 1, NM_002701) and a short (variant 2, NM_203289) transcript. Only variant 1 is a key regulator of pluripotency. Hence, it is important to be able to distinguish this transcript from variant 2 and from the many pseudogenes present in the genome. Previous studies on the expression of POU5F1 were, however, usually carried out without c
Angiogenesis is a key event in cancer progression and therefore a promising target in cancer treatment. Galectin-1, a β-galactoside binding lectin, is up-regulated in the endothelium of tumors of different origin and has been shown to be the target for anginex, a powerful anti-angiogenic peptide with anti-tumor activity. Here we show that when bound to anginex, galectin-1 binds various glycoprotei
The Variation Ontology (VariO) is used for describing and annotating types, effects, consequences and mechanisms of variations. To facilitate easy and consistent annotations, the online application VariOtator was developed. For variation type annotations VariOtator is fully automated, accepting variant descriptions in Human Genome Variation Society (HGVS) format, and generating VariO terms, either
Although the direction of loads applied to the proximal human femur is unpredictable during sideways fall, most in vitro and numerical simulations refer to a single loading condition (15° internal rotation; 10° adduction), which has been anecdotally suggested in the 1950s. The aim of the present study was to improve in vitro simulations of sideways falls on the proximal femur. An in vitro setup w
Titanium dioxide (TiO2) has very high affinity for phosphopeptides and in recent years it has become one of the most popular methods for phosphopeptide enrichment from complex biological samples. Peptide loading onto TiO2 resin in a highly acidic environment in the presence of 2,5-dihydroxybenzoic acid (DHB), phthalic acid, lactic acid, or glycolic acid has been shown to improve selectivity signif
Colophony is not used as a fragrance ingredient. However, colophony is a well-established marker of fragrance contact allergy(2-4) . Colophony was therefore included as a fragrance allergy marker in our recent paper in BJD on contact allergy in the general population (prevalence 1.0%; 95%-CI 0.6%-1.3%)(5) . When including colophony as a fragrance marker in the article on fragrance contact allergy(
This paper investigates how & to what degree English is used in specific elite domains in Sweden through analysis of (1) language requirements to participate in undergraduate & graduate programs at competitive institutions, & (2) language qualifications & language use patterns in elite professions. We find that English is used pervasively, but not exclusively. The paper also explor
