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The Large Interferometer For Exoplanets (LIFE) : A space mission for mid-infrared nulling interferometry

The Large Interferometer For Exoplanets (LIFE) is a proposed space mission that enables the spectral characterization of the thermal emission of exoplanets in the solar neighborhood. The mission is designed to search for global atmospheric biosignatures on dozens of temperate terrestrial exoplanets and it will naturally investigate the diversity of other worlds. Here, we review the status of the m

Vocational awe is (not) enough : Learnings from early adopters of serious illness communication

CONTEXT: As part of a broader institutional initiative, the serious illness care program was implemented in a multi-site academic primary care practice. After 2 years, a minority was observed to be documenting serious illness conversations routinely.OBJECTIVES: We aimed to learn about the motivations and actions of clinicians who routinely conducted and documented serious illness conversations.MET

Measuring cohesive law of wood adhesive bonds for engineering of timber joints and products

Accurate prediction of crack growth and strength in glued timber joints and components can be achieved by using cohesive laws in constitutive models. These laws represent the traction-separation relationship that measures the stress transmitted between crack faces in a cohesive zone, and can be obtained directly from experiments. However, studies on measuring the cohesive laws of wood adhesive bon

The Anatomy of Interprofessional Collaboration Around Recommendations in the Intensive Care Unit: An Exploration After Serious Illness Care Training

Background:Serious illness conversations are an iterative, interprofessional, team-based process that includes recommendations about medical care. Yet, it is not clear how clinicians in different role groups work together in this process.Objectives:We sought to examine how interprofessional clinicians in the medical intensive care unit (MICU) who were trained in the serious illness care program (S

The role of mathematics in the teaching and learning of physics

This paper discusses the role of mathematics in physics teaching and learning. The intention and strength of science is to describe what happens in the realworld by organizing explanations through theories and theoretical models. It has been widely suggested that learning in science is influenced by views about the nature of scientific knowledge. Furthermore, mathematics is an inherent part of the

Psychosocial stress and male gonadal function

Normal ageing in men is associated with a physiological decline in testosterone levels, but adverse environmental or psychosocial factors may also impair testosterone secretion and cause secondary biological changes. In a number of observational or experimental studies in both animals and man, it has been possible to study the influences on gonadal function of stressful life situations. To underst

CNS progenitor cells promote a permissive environment for neurite outgrowth via a matrix metalloproteinase-2-dependent mechanism

Transplantation of progenitor cells to the CNS has shown promise in neuronal and glial replacement and as a means of rescuing host neurons from apoptosis. Here we examined the effect of progenitor grafts on neurite extension in the degenerating retina of rd1 ( retinal degeneration 1) mice. Transplantation of retinal progenitor cells induced increased matrix metalloproteinase-2( MMP2) secretion, pa

Aggressive lymphoma

Popular Abstract in Swedish Aggressiva lymfom utgör en undergrupp av en typ av elakartade (maligna) tumörer, maligna lymfom. Cellerna i dessa tumörer utgår från en typ av vita blodkroppar, lymfocyter, vilka har en central roll i kroppens immunförsvar. Maligna lymfom utgör ca 4% av alla fall av elakartade tumörer i Sverige, vilket motsvarar ca 1700 nya fall per år. I västvärlden ökar dock antalet fAggressive lymphoma is a rapidly growing tumour of lymphocyte origin, potentially curable with chemotherapy. In a trial by the Nordic Lymphoma Group, 405 patients with aggressive lymphoma were included, and randomised to receive either the standard chemotherapy regimen, CHOP, or a weekly multidrug regimen, MACOP-B. In this trial, MACOP-B was not superior in terms of response, failure-free or overa

New improved method for 2D arterial wall movement measurements

We have recently reported that the inner layers of the arteries, the intima-media complex, of common carotid artery, move as much in the longitudinal direction as in the radial direction, during the cardiac cycle. In order to study this phenomenon we have developed a high-resolution ultrasonic method that can simultaneously record both the longitudinal and the radial movements of the arterial wall

ILBC - A linear predictive coder with robustness to packet losses

In this paper, we discuss the internet low bit rate codec (iLBC) with an emphesis on the frame-independent longterm prediction. The frame-independent long-term prediction is a method to exploit pitch-lag correlations in the encoding of speech without suffering multiple-frame speech degradation in connection with transmission loss. We present mean opinion scores for the iLBC codec and show by means

Caring as sharing. Negotiating the moral boundaries of receiving care

Informal caregiving is increasingly considered a health care delivery-resource within the North European welfare states. While ‘informal’ often refers to non-professional, ‘caregiving’ connotes both affective concern (caring about) and practical action (caring for). This duality of meanings, however, often refers to the one direction in which care is given. Care, we suggest, is relational and also

The earth system feedbacks that matter for contemporary climate

Here, we discuss the feedback processes that determine the nature and rates of climatic changes in response to climate forcing. We explain the differences in the characteristic behaviour of biophysical and biogeochemical feedbacks, and describe the means by which feedbacks can be identified using models and observational data, and their strength quantified. Improved understanding of these kinds of

Qualitative cross-country comparison of whether, when and how people diagnosed with lung cancer talk about cigarette smoking in narrative interviews

OBJECTIVES: To compare and examine whether, when and how patients with lung cancer in three countries, with different survival rates, talk about cigarette smoking and its relationship with help-seeking. DESIGN: A qualitative cross-country comparison with analysis of narrative interviews. SETTING: Participants in Sweden, Denmark and England were interviewed during 2015-2016. Interviews, using a nar

Prolonged opioid use after distal radius fracture

BACKGROUND: Prolonged opioid use (more than 90 days) after injury puts the patient at risk for adverse effects. We investigated the patterns of opioid prescription after distal radius fracture and the effect of pre- and post-fracture factors on the risk for prolonged use.METHODS: This register-based cohort study uses routinely collected health care data, including purchases of prescription opioids

Influence of AFIR's charging station spacing requirement on heavy-duty vehicle electrification rate

Den snabba utvecklingen av elektrifiering av vägtransporter i Sverige kräver forskningsbaserade beslut om placeringen av laddinfrastruktur. Europeiska unionens (EU) nya förordning för infrastruktur för alternativa bränslen (AFIR) specificerar det maximala tillåtna avståndet mellan offentliga snabbladdningsstationer (FCS) för tunga lastbilar längs det transeuropeiska transportnätverket (TEN-T). EffThe rapid progression of the electrification of road transport in Sweden requires effective research based decisions on the location of charging infrastructure. The new European Union (EU) regulation for alternative fuel infrastructure (AFIR) specifies the maximum allowed distance between public fast-charging stations (FCSs) for heavy-duty trucks along the Trans-European Transport Network (TEN-T).