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PURPOSE: Techniques for endovascular thrombectomy in acute ischemic stroke due to medium or distal vessel occlusions (MDVO) need to be improved, and first-line aspiration is emerging as a promising technique. The objective was to describe first-pass and final reperfusion rates with a triaxial direct aspiration first pass technique (ADAPT) and a novel, quadriaxial technique (QUATTRO-ADAPT) using RE
Background: Magnetic resonance imaging (MRI) is recommended by guidelines to evaluate the severity of brain ischemia after cardiac arrest for functional outcome prediction. However, standardized assessment criteria are lacking. We have developed a semi-quantitative Cardiac Arrest Brain Ischemia (CABI) score to assess the extension of brain ischemia on MRI. Objectives: To evaluate the prognostic pe
Provision of assistive technologies (AT) is strongly connected to applying a person-centred approach, with focus on exploring the person’s individual abilities, needs and desires, to enable provision of matching AT. In the process of provision, it is also important to assess and facilitate the person’s understanding of how to use the AT, to enhance optimal usage and enable AT integration in everyd
Objectives: Our aim was to compare direct costs for single pill combinations (SPCs) and free-drug combinations for hypertension treatment. Methods: We focused on Australia as a case study and reviewed total costs, and for the patient and government. We reviewed the Australian “Pharmaceutical Benefits Scheme item drug map” considering different thresholds for the government safety net. Total costs
The chapter focuses on how process is reviewed in the general framework of EU legal analysis applicable to national pre-authorisation schemes. By examining the model of judicial review developed by the Court of Justice in this regard, I hope to enrich the discussion on what process federalism within the Union can look like and how it may function. After some brief explanations regarding the charac
Our understanding of public support for climate policies predominantly stems from studies in the Global North and a focus on isolated policy types. Here, we examine how public support for four different climate policy types and the effect of ideological explanatory variables on such support vary among countries of the Global North and Global South. We surveyed representative samples of each three
Evaluating the effect of measurement errors on either adaptive or simultaneous control charts has been a topic of interest for the researchers in the recent years. Nevertheless, the effect of measurement errors on both adaptive and simultaneous monitoring control charts has not been considered yet. In this paper, through extensive numerical studies, we evaluate the effect of measurement errors on
Introduction: Elevated pulmonary vascular resistance (PVR) is observed in both physiological and pathological states. Pulmonary hypertension (PH) is a condition associated with significant morbidity and mortality in neonates and children and curative pharmacotherapy is lacking in most cases. In utero, a high PVR allows for blood to bypass the lungs through the open ductus arteriosus (DA). Vascular
Liquid crystalline nanoparticles (LCNPs), e.g. cubosomes and hexosomes, are receiving more and more attraction as drug delivery vehicles. Dry powder formulation that forms LCNPs upon hydration can be advantageous to make new routes of administration accessible. In this work, we investigate use of three disaccharides (lactose, trehalose and sucrose) as protective matrices for glycerol monooleate ba
Against the backdrop of the current geopolitical situation, logistics preparedness emerges as a pivotal area of focus for defence supply chains. Despite the critical role of commercial suppliers, research on utilising these in defence logistics and supply chains remains scarce. Adopting a supply chain governance lens, we have conducted a systematic literature review to provide an overview of exist
The aim of this chapter is to analyse and describe how teachers’ use of theoretical conjectures in instruction during a Learning Study (LeaS) process affected high-functioning autism spectrum disorder (HFASD) students’ learning outcomes when following the national curriculum. Participants were students in grades 7 to 9 (n = 11) and their teachers (n = 5). The 11 adolescents (4 females and 7 males)
Emotional communication, especially through social media platforms, has become a contemporary populist threat. While this phenomenon has been studied in for example news media and social movements, we know less about its influence on civil society organizations, despite their pluralism being a centerpiece in a vibrant democracy. More specifically, we do not know if social media make civil society
Platform trials have become widely adopted across multiple disease areas over recent years, however, guidelines for operationalising these trials have not kept pace. We outline a series of documents that summarise the statistical components, and implicit processes, of the Staphylococcus aureus Network Adaptive Platform (SNAP) trial to provide an informal template for other researchers and reviewer
Patients with dementia experience a steady deterioration in cognitive function that increases mortality and impairments. Moreover, dementia is also anticipated to increase significantly in prevalence as the world's population ages, placing a strain on healthcare systems throughout the globe. Hence, early identification and prediction of dementia are essential due to timely treatments, enhanced pat
Hydrogen energy plays a pivotal role in the sustainable energy transition. Methanol steam reforming offers an efficient route for decentralized hydrogen production, yet catalyst limitations persist. This work employs entropy engineering to design lanthanide perovskite catalysts via sol-gel synthesis. Structural analyses reveal entropy-driven lattice distortion, enhanced disorder, and elevated oxyg
Few existing studies have delved into individual-level attitudes towards the exchange of sexual services for payment, leaving a significant gap in our understanding. Various studies have speculated about how certain demographic factors and attitudes may shape people's perceptions of causes and consequences relating to such exchanges, but none have directly investigated this topic. To bridge this g
Pituitary tumours, originating from endocrine cells of the anterior pituitary, are quite common, and in most cases well-controlled by surgery or medical treatment. However, a small subset of pituitary tumours presents with multiple local recurrences or tumour progression despite combined surgical, medical or radiotherapeutic treatment. These are known as aggressive pituitary tumours (APT); also ca
Artificial intelligence (AI) methods are powerful tools for biological image analysis and processing. High-quality annotated images are key to training and developing new algorithms, but access to such data is often hindered by the lack of standards for sharing datasets. We discuss the barriers to sharing annotated image datasets and suggest specific guidelines to improve the reuse of bioimages an
The intervention Balancing Everyday Life™ (BEL) helps service users achieve a balance among everyday activities and enhance personal recovery. BEL builds upon research for people with mental illness and on evidence from earlier activity-based interventions. This methodological paper presents the theoretical basis for BEL, which rests on five pillars of theories and models. Further, the BEL topics
