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Background Patient crowding in emergency departments (ED) is a common challenge and associated with worsened outcome for the patients. Previous studies on biomarkers in the ED setting has focused on identification of high risk patients, and and the ability to use biomarkers to identify low-risk patients has only been sparsely examined. The broader aims of the TRIAGE study are to develop methods t

Background: Whether long-term effectiveness differs between anti-tumour necrosis factor (anti-TNF) agents is unknown. Aims: To examine drug survival of first-line anti-TNF agents and identify predictors of discontinuation. To reduce channelling bias, we also compared drug survival of the second anti-TNF. Methods: Biologic-naïve patients (N = 955) recorded in the Swedish IBD Quality Register (SWIBR

Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers o

Companies always strives to acheive as eective inventory control as possible. At the same time, a suciently high delivery accuracy to satisfy the customer is pursued. One prerequisite for successfully accomplishing this is to anticipate customer demand in advance. An approximation of the demand in advance is called forecasting. Forecasting implies that dierent techniques are used to predict future

Försäkringsbolag behöver identifiera och hantera en stor mängd potentiellt bedrägliga försäkringsanspråk från deras kunder. Därför har försäkringsbolag en rad system för att försöka identifiera vilka anspråk som är bedrägliga och vilka som inte är det. Med den senaste utvecklingen inom maskininlärning och särskilt inom området för språkbehandling (NLP) kan dessa tekniker eventuellt användas för atMachine-Learning can sometimes see things we as humans can not. In this thesis we evaluated three different Natural Language Procces-techniques: BERT, word2vec and linguistic analysis (UDPipe), on their performance in detecting insurance fraud based on transcribed audio from phone calls (referred to as audio data) and written text (referred to as text-form data), related to insurance claims. We al

The self-assembly of the trifluoroacetate salt of the short peptide (ala)(6)-lys (A(6)K) in water has been investigated by cryo-transmission electron microscopy and small-angle X-ray scattering. For concentrations below ca. 12%, the peptide does not self-assemble but forms a molecularly dispersed solution. Above this critical concentration, however, A(6)K self-assembles into several-micrometer-lon

As a second major result we show how to combine the path cover technique with LCA solutions for dags with small depth [9]. Our algorithm attains the best known upper time bound for this problem of O(n 2.575). However, most notably, the algorithm performs better on a vast amount of input dags, i.e. dags that do not have an almost linear-sized subdag of extremely regular structure. Finally, we appl

Abstract in French Cet article présente le contexte culturel et archéologique des os fossiles humains de la Grotte Muierii que nous datons de 30 150 ± 800 14C ans BP (Before Present) ou 34 810 ± 927 cal. ans BP (ans calibrés Before Present), et de la Grotte Cioclovina, datés de 29 000 ± 700 14C ans BP ou 33 540 ± 832 cal. ans BP, dans les Carpates méridionales.. Ils s’insèrent parmi les plus ancieThis paper presents the cultural and archaeological context of the human fossil bones from Muierii Cave, dated by us to the age of 30 150 ± 800 14C years BP (Before Present) or 34 810 ± 927 cal years BP (calibrated years Before Present), and from Cioclovina Cave, dated to the age of 29 000 ± 700 14C years BP or 33 540 ± 832 cal years BP, in the Southern Carpathians. These are among the most ancien

The acute effects of recombinant human interleukin-1 beta (rIL-1) on basal and glucose-stimulated insulin release were investigated in the isolated perfused pancreas. At a concentration of 20 μg/l rIL-1 had no effect on basal insulin release, but increased the total amount of insulin released during first and second phase insulin release in response to 20 mmol/l D-glucose in the rat pancreas (P <

A new amperometric biosensor for ethanol, based on carbon paste electrode modified with alcohol dehydrogenase (ADH), polyethylenimine (PEI) and using a phenothiazine derivative (DDDP; 16H,18H-dibenzo[c,1]7,9-dithia-16,18-diazapentacene) as redox mediator for NADH recycling, was developed. The biosensor response is the result of mediated oxidation of NADH, generated in the enzymatic reaction betwee

Den svenska missbruks- och narkotikamodellen bygger på en restriktiv straffrättslig kontroll med ett narkotikafritt samhälle som mål. Trots detta har Sverige idag högst narkotikarelaterad dödlighet i Europa. Portugal använder istället en modell där skademinimering är centralt och förvärv och innehav avsett för eget bruk samt eget bruk är avkriminaliserat. I dagsläget verkar också Norge ta in på etThe Swedish drug control strategy is based on restrictive criminal law where the goal is a society free from illicit drugs. However, today Sweden has the highest drug-related mortality in Europe. Countries like Portugal use a different model where harm reduction is central and acquisitions, personal possession and consumption are decriminalized. Norway is also taking an interest in switching to a