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Objective: To report on safety and effectiveness of subcutaneous cladribine (Litak®) in multiple sclerosis (MS) patients. Methods: Litak® was offered to MS-patients irrespective of disease course. Litak® 10 mg was administered for 3–4 days during week 1. Based on lymphocyte count at week 4, patients received another 0–3 doses at week 5. A second course was administered 11 months later. Follow-up i
The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded in 2018, with the aim to promote cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic peripheral artery was selected as the very first topic to be investigated by the federation. In this second paper, differ
Importance: Human genetics and studies in experimental models support a key role of monocyte-chemoattractant protein-1 (MCP-1) in atherosclerosis. Yet, the associations of circulating MCP-1 levels with risk of coronary heart disease and cardiovascular death in the general population remain largely unexplored. Objective: To explore whether circulating levels of MCP-1 are associated with risk of inc
The impacts of global climate change on different aspects of humanity's diverse life-support systems are complex and often difficult to predict. To facilitate policy decisions on mitigation and adaptation strategies, it is necessary to understand, quantify, and synthesize these climate-change impacts, taking into account their uncertainties. Crucial to these decisions is an understanding of how im
The Al-Mg phase diagram has been reinvestigated in the vicinity of the stability range of the Samson phase, β-Mg2Al3 (cF1168). For the composition Mg38.5Al61.5, this cubic phase, space group Fd3̄m (no 227), a = 28.242(1) Å, V = 22526(2) Å3, undergoes at 214°C a first-order phase transition to rhombohedral β′-Mg2Al3, (hR293), a = 19.968(1) Å, c = 48.9114(8) Å, V = 16889(2) Å3, (i.e. 22519 Å3 for th
Recent genetic studies have identified alleles associated with opposite effects on adiposity and risk of type 2 diabetes. We aimed to identify more of these variants and test the hypothesis that such favorable adiposity alleles are associated with higher subcutaneous fat and lower ectopic fat. We combined MRI data with genome-wide association studies of body fat percentage (%) and metabolic traits
Projectile Coulomb excitation experiments were performed at HIE-ISOLDE at CERN with the radioactive ion beams of 140Nd and 142Sm. Ions with an energy of 4:62 MeV/A were impinging on a 1.45 mg/cm2 thick 208Pb target. The γ-rays depopulating the Coulomb-excited states were recorded by the HPGe-array MINIBALL and scattered particles were detected by a double-sided silicon strip detector. Experimental
Insight into how environmental change determines the production and distribution of cyanobacterial toxins is necessary for risk assessment. Management guidelines currently focus on hepatotoxins (microcystins). Increasing attention is given to other classes, such as neurotoxins (e.g., anatoxin-a) and cytotoxins (e.g., cylindrospermopsin) due to their potency. Most studies examine the relationship b
How the patterns of niche occupancy vary from species-poor to species-rich communities is a fundamental question in ecology that has a central bearing on the processes that drive patterns of biodiversity. As species richness increases, habitat filtering should constrain the expansion of total niche volume, while limiting similarity should restrict the degree of niche overlap between species. Here,
Context. After more than 50 years, astronomical research still struggles to reconstruct the history of lithium enrichment in the Galaxy and to establish the relative importance of the various 7Li sources in enriching the interstellar medium (ISM) with this fragile element. Aims. To better trace the evolution of lithium in the Milky Way discs, we exploit the unique characteristics of a sample of op
Wind turbines are important for achieving renewable energy goals, but present a considerable threat to wildlife, especially birds and bats. This study reports 41 confirmed collisions of GPS-tracked Red Kites (Milvus milvus) with wind turbines across Europe (2017–2024). We compared environmental and turbine-specific factors during collisions and non-collision movements within 500 m of turbines. Col
Objective. In patients with axial spondyloarthritis (axSpA) initiating secukinumab (SEC), we aimed to identify baseline (treatment start) predictors of achieving low disease activity (LDA) after 6 months, as measured by the Axial Spondyloarthritis Disease Activity Score using C-reactive protein (ASDAS-CRP) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), as well as treatment contin
Background: – The use of antibiotic-loaded bone cement (ALBC) in primary total knee arthroplasty (TKA) is debated. Some argue that ALBC might only be justified in high-risk patients. This study assessed the effectiveness of ALBC vs. plain bone cement (PBC) in reducing risk of revision for periprosthetic joint infection (PJI) in TKA patients considered to have a high risk of infection.Methods: – Co
Evolution has traditionally been a historical and descriptive science, and predicting future evolutionary processes has long been considered impossible. However, evolutionary predictions are increasingly being developed and used in medicine, agriculture, biotechnology and conservation biology. Evolutionary predictions may be used for different purposes, such as to prepare for the future, to try an
People with obesity commonly face a pervasive, resilient form of social stigma. They are often subject to discrimination in the workplace as well as in educational and healthcare settings. Research indicates that weight stigma can cause physical and psychological harm, and that affected individuals are less likely to receive adequate care. For these reasons, weight stigma damages health, undermine
A unified syntax for logophors and anaphors: evidence from verbal agreement in Tamil GLOW 36 Colloquium, Lund University, April 3, 2013 Sandhya Sundaresan, University of Tromsø sandhya.sundaresan@uit.no, https://sites.google.com/site/sndhysndrsn 1 Overview Based on evidence from verbal agreement triggered under an anaphor, in the Dravidian language Tamil, I will argue that anaphoricity and logopho
MastersDissertationColdBentGlass Master’s Dissertation Structural Mechanics Report TV SM -5280 M O H A M A D BA RA D EY M O D ELLIN G O F C U R V ED G LA SS ELEM EN TS - C o ld -B en t G lass an d Sim p lifi ed M o d els MOHAMAD BARADEY MODELLING OF CURVED GLASS ELEMENTS Cold-Bent Glass and Simplifi ed Models DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF STRUCTURAL MECHANICS ISRN LUTVDG/TVSM--25
https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5280.pdf - 2026-04-20
Microsoft Word - 00ktiitel38-1-4 Sign Systems Studies 38(1/4), 2010 Cross-modal iconicity: A cognitive semiotic approach to sound symbolism Felix Ahlner, Jordan Zlatev Centre for Languages and Literature, Lund University Box 201, 221 00, Lund, Sweden e-mail: felix.ahlner@gmail.com, jordan.zlatev@ling.lu.se Abstract. It is being increasingly recognized that the Saussurean dictum of “the arbitrarine
https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_ccs/AhlnerZlatev2011.pdf - 2026-04-20
LUMES LUND UNIVERSITY INTERNATIONAL MASTER'S PROGRAMME IN ENVIRONMENTAL SCIENCE A SYSTEM'S ApPROACH FOR UNDERSTANDING THE DYNAMIC COMPLEXITY IN MANAGING SCARCE W ATER REso URCES CASE STUDY ON MANAGEMENT OF SCARCE W ATER RESOURCES IN THE lIASHEMITE KINGDOM OF JORDAN MASTER' S THESIS BY ROBA EL-GHADBAN Närlundavägen 13 25275, Helsingborg, Sweden Tel.: + 42 28 49 24 E-mail: env98reg@student3.1u.se, r
https://www.lumes.lu.se/sites/lumes.lu.se/files/el-ghadban_roba.pdf - 2026-04-22
