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Landscape of somatic mutations in 560 breast cancer whole-genome sequences

We analysed whole-genome sequences of 560 breast cancers to advance understanding of the driver mutations conferring clonal advantage and the mutational processes generating somatic mutations. We found that 93 protein-coding cancer genes carried probable driver mutations. Some non-coding regions exhibited high mutation frequencies, but most have distinctive structural features probably causing ele

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

Background: Most BRCA1 or BRCA2 mutation carriers have inherited a single (heterozygous) mutation. Transheterozygotes (TH) who have inherited deleterious mutations in both BRCA1 and BRCA2 are rare, and the consequences of transheterozygosity are poorly understood. Methods: From 32,295 female BRCA1/2 mutation carriers, we identified 93 TH (0.3 %). "Cases" were defined as TH, and "controls" were sin

Systematic investigation of projectile fragmentation using beams of unstable B and C isotopes

Background: Models describing nuclear fragmentation and fragmentation fission deliver important input for planning nuclear physics experiments and future radioactive ion beam facilities. These models are usually benchmarked against data from stable beam experiments. In the future, two-step fragmentation reactions with exotic nuclei as stepping stones are a promising tool for reaching the most neut

A reference panel of 64,976 haplotypes for genotype imputation

We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies, and it can help to discover and refine causal loci.

Coulomb dissociation of N 20,21

Neutron-rich light nuclei and their reactions play an important role in the creation of chemical elements. Here, data from a Coulomb dissociation experiment on N20,21 are reported. Relativistic N20,21 ions impinged on a lead target and the Coulomb dissociation cross section was determined in a kinematically complete experiment. Using the detailed balance theorem, the N19(n,γ)N20 and N20(n,γ)N21 ex

Beyond the neutron drip line: The unbound oxygen isotopes O-25 and O-26

The very neutron-rich oxygen isotopes O-25 and O-26 are investigated experimentally and theoretically. The unbound states are populated in an experiment performed at the R3B-LAND setup at GSI via proton-knockout reactions from F-26 and F-27 at relativistic energies around 442 and 414 MeV/nucleon, respectively. From the kinematically complete measurement of the decay into O-24 plus one or two neutr

Variants in MTNR1B influence fasting glucose levels

To identify previously unknown genetic loci associated with fasting glucose concentrations, we examined the leading association signals in ten genome-wide association scans involving a total of 36,610 individuals of European descent. Variants in the gene encoding melatonin receptor 1B (MTNR1B) were consistently associated with fasting glucose across all ten studies. The strongest signal was observ

Measurement of inclusive jet and dijet cross sections in proton-proton collisions at 7 TeV centre-of-mass energy with the ATLAS detector

Jet cross sections have been measured for the first time in proton-proton collisions at a centre-of-mass energy of 7 TeV using the ATLAS detector. The measurement uses an integrated luminosity of 17 nb(-1) recorded at the Large Hadron Collider. The anti-k(t) algorithm is used to identify jets, with two jet resolution parameters, R = 0.4 and 0.6. The dominant uncertainty comes from the jet energy s

TVBA-5062HO.indd

TVBA-5062HO.indd Master’s Dissertation Engineering Acoustics Report TV BA -5062 SEM IR C A BA N EVA LU A TIO N O F O U TD O O R EN V IRO N M EN T IN PRESCH O O LS U SIN G TH E SO U N D SCA PE A PPRO A CH SEMIR CABAN EVALUATION OF OUTDOOR ENVIRONMENT IN PRESCHOOLS USING THE SOUNDSCAPE APPROACH DEPARTMENT OF CONSTRUCTION SCIENCES DIVISION OF ENGINEERING ACOUSTICS ISRN LUTVDG/TVBA--20/5062--SE (1-77)

https://www.akustik.lth.se/fileadmin/tekniskakustik/publications/tvba5000/webTVBA5062.pdf - 2026-05-02

WPSS_Svavarsdottir_2024JB_HS_24juni

WPSS_Svavarsdottir_2024JB_HS_24juni Working Papers in Scandinavian Syntax 110 (2024), 14–53 Lexical Case Absorption in Icelandic Raising Hrefna Svavarsdóttir University of Iceland Abstract The following paper examines case marking variations in Icelandic raising infinitives in instances where a lexical case (here of accusative or dative subjects) yields to a structural case in subject-to-object ra

https://projekt.ht.lu.se/fileadmin/user_upload/sol/ovrigt/projekt_grimm/working_papers/2024-jun/Svavarsdottir.pdf - 2026-05-02

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Supervising Interdisciplinary Theses TEACHING FOR SUSTAINABILITY | 12 OCTOBER 2023 Provide the protected time and space to reflect on your own approach to supervising interdisciplinary thesis, inspired by the content and discussions during the seminar Invitation • Becoming present – Calming breaths – Check-in with your body – Set your intention – Something else – Nothing else Agenda • Introduction

https://www.ahu.lu.se/fileadmin/user_upload/ahu/Images/Teaching_for_Sustainability/Seminars/SLIDES_Supervising_Interdisciplinary_Thesis_12Oct2023.pdf - 2026-05-02

Abstracts

Abstracts | Centre for Mathematical Sciences Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally ide

https://www.maths.lu.se/english/research/seminars/hypoellipticity-in-lund-2025/abstracts/ - 2026-05-02

Recent publications

Recent publications | LUMLAC Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiable inform

https://www.mlc.lu.se/major-biophotonics-facilities/recent-publications/ - 2026-05-02

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Exercise for Optimal control – Week 3 Choose 1.5 problems to solve. Disclaimer This is not a complete solution manual. For some of the exercises, we provide only partial answers, especially those involving numerical problems. If one is willing to use the solution manual, one should judge whether the solutions are correct or wrong by him/herself. Exercise 1. Consider a harmonic oscillator ẍ + x =

https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/Optimal_Control/2023/ex3-sol.pdf - 2026-05-03

Asylum Seeker Situation Urgent in Europe

Asylum Seeker Situation Urgent in Europe Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods Focus Areas Business and Human Rights Internat

https://rwi.lu.se/2015/04/21/asylum-seeking-situation-urgent/ - 2026-05-03

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Promoting Gender Equality Methods, results and lessons learned Introduction The Raoul Wallenberg Institute of Human Rights and Humanitarian Law is deeply ro- oted in the field of gender equality promotion. The Institute seeks to address human rights and gender equality together, concentrating on their common and complimentary as- pects. This approach comes from an under- standing that gender equal

https://rwi.lu.se/app/uploads/2017/06/Gender-Equality-Brief.pdf - 2026-05-03

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L3: Density functions and sum-of-squares methods ○ Lyapunov Stabilization Computationally Untractable ○ Density Functions ○ “Almost” Stabilization Computationally Convex ○ Duality Between Cost and Flow ○ Sum-of-squares Optimization ○ Examples Literature. Density functions: Rantzer, Systems & Control Letters, 42:3 (2001) Synthesis: Prajna/Parrilo/Rantzer, TAC 49:2 (2004) SOSTOOLS and its Control Ap

https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/NonlinearControl/2017/fu_lec03_2017eight.pdf - 2026-05-03

HybridLabs

HybridLabs LTH:s 12:e Pedagogiska Inspirationskonferens, 7 december 2023 Hybrid Data Communication Lab – a Case Study Jens A Andersson, Sara Willhammar, and Ashkan Sheikhi, EIT Abstract—Due to restrictions following the Covid-19 pandemic, major changes regarding teaching have been called for. Since students’ presence in lab classrooms has been very restricted also physical labs have had to be tran

https://www.lth.se/fileadmin/cee/genombrottet/konferens2023/E4_Andersson_etal.pdf - 2026-05-03

Rights in Russia - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

Rights in Russia - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Methods

https://rwi.lu.se/blog/rights-in-russia/ - 2026-05-03