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Context: Previous randomized trials have suggested an association between radioiodine treatment for Graves' hyperthyroidism and thyroid-associated ophthalmopathy (TAO). Objectives: The aim of the study was to compare the occurrence of worsening or development of TAO in patients who were treated with radioiodine or antithyroid drugs. Design: We conducted a randomized trial (TT 96) with a follow-up

Denna bok handlar om ett förändringsprojekt vid Lunds universitet som syftade till att förkorta studietiderna utan att kandidat- och magisteruppsatsernas vetenskapliga kvalitet påverkades negativt. Det omedelbara resultatet blev att andelen uppsatser som blev färdiga inom föreskriven tidsram ökade från under 10 % till över 50 % samtidigt som deras vetenskapliga kvalitet inte försämrades. I boken b

The plant polysaccharide degradative potential of Aspergillus nidulans was analysed in detail and compared to that of Aspergillus niger and Aspergillus oryzae using a combination of bioinformatics, physiology and transcriptomics. Manual verification indicated that 28.4% of the A. nidulans ORFs analysed in this study do not contain a secretion signal, of which 40% may be secreted through a non-clas

What conformations do protein molecules populate in solution? Crystallography provides a high-resolution description of protein structure in the crystal environment, while NMR describes structure in solution but using less data. NMR structures display more variability, but is this because crystal contacts are absent or because of fewer data constraints? Here we report unexpected insight into this

The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). In addition, patients with giant cell arteritis (GCA) were also investigated because o

A novel strategy is presented for designing peptides with specific metal-ion chelation sites, based on linking computationally predicted ion-specific combinations of amino acid side chains coordinated at the vertices of the desired coordination polyhedron into a single polypeptide chain. With this aim, a series of computer programs have been written that 1) creates a structural combinatorial libra

Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world. AMD is a multifactorial disorder but complement-mediated inflammation at the level of the retina plays a pivotal role. Oral zinc supplementation can reduce the progression of AMD but the precise mechanism of this protective effect is as yet unclear. We investigated whether zinc supplementation directly a

Betydelsen och innebörden av konsumenttjänstlagens fackmässighetsbegrepp som återfinns i 4 § KtjL är svårdefinierbar. Lagen som tillämpas på flera olika typer av tjänster saknar en specifik definition på en tjänsts praktiska utförande. Begreppet fackmässighet baseras på hur branschen ser ut, vilka metoder som används och vilka regler som gäller i nuläget. Detta arbete har haft som syfte att redaThe Consumer Services Act´s professional execution, which can be found in § 4 KtjL, has generated a wide array of interpretations. The law is applicable to several different varieties of services and therefor lacks a specific and coherent definition of how a service should be performed. The concept of professionalism is based on the type of business, what methods are used and which rules that curr

Neutralitetsprincipen har sedan länge varit en starkt etablerad och mycket vik-tig princip på idrottens område. Att stå fri från politiskt inflytande och att stå neutrala i politiska frågor grundar sig i viljan att vara en inkluderande och accepterande arena där alla idrottare kan tävla på lika villkor, oavsett politiska eller religiösa bakgrunder. Idrottsrörelsen vill vara en värld dit polariseraThe principle of neutrality is a well-established and important principle within the sports world. The freedom from political influences and the ability to remain neutral in political matter is founded on the wish to be an inclusive and accepting arena, where athletes compete on the same terms, regardless of political or religious background. The sport world’s main objective is to be an impartial

Uppsatsen har som syfte att granska den särskilda skadeståndsskyldigheten som åligger det allmänna enligt SKL 3:2. Särskilt i fokus är vilken mån detta skadestånd kan jämkas genom den allmänna jämkningsparagrafen i SKL 6:1. Det finns tidigare forskning om det allmännas skadeståndsansvar vid felaktig myndighetsutövning, det finns även tidigare forskning kring jämkning av skadestånd. Det saknas dockThe purpose of this essay is to review the special liability for damages that is placed on the public sector according to SKL 3:2. Particularly in focus is to witch extent this liability can be reduced through the general adjustment clause in SKL 6:1. There is previous research on the public's liability for damages caused by wrongful exercise of authority, there is also previous research on th

Uppsatsen handlar om plattformsekonomin och hur arbetena som skapas i den regleras i svensk arbetsrätt. Skyddet den svenska arbetsrätten ger är primärt för arbetstagare. Därför är syftet med uppsatsen att se vad som talar för respektive emot att plattformsarbetare är arbetstagare. Uppsatsen syftar också att utreda ifall det finns ett behov för närmare reglering av plattformsarbeten. För att kunThis thesis concerns the platform economy and how the works generated by it is regulated in Swedish labor law. The protection the Swedish labor law gives is mainly for employees. Therefore the purpose of this thesis is to see what argues for and against that platform workers should be considered employees. The thesis also aims to determine whether there is a need for closer regulation of platform

År 2009 reformerades det administrativa förfarandet för tillståndsprövningar av vindkraftverk, delvis för att en större vindkraftsutbyggnad skulle komma till stånd men också som nödvändig en åtgärd för att Sverige skulle uppfylla sina skyldigheter i 2009 års förnybarhetsdirektiv. Tidigare hade en ansökning om att få bygga vindkraft inneburit dubbla process- och tillståndsförfaranden enligt både PlIn 2009 the Swedish legislature regarding the administrative procedure applicable to wind energy projects was amended, in part to increase wind power construction but also as a measure to fulfil Sweden’s obligations stemming from the 2009 Renewables directive. As a result, the dual process- and permit procedure under both the Plan and Building Act and the Environmental Code was abolished. Instead,

The issue of food waste is a growing global problem having social, environmental and economic consequences. Over the recent years, this issue has received attention at International, national, regional and local levels. One such example is the case of Malmö which, in their Sustainable food policy has identified food waste as one of the key areas to reduce Greenhouse gas emission down to 40% of 200

Sustainable development “which meets the needs of the present without compromising the ability of future generations to meet their own needs,” (WCED 1987) is a global development objective of paramount importance. However, on the ground, ‘sustainable development’ is – in my experience – often little more than a buzzword for securing grants. From a strong sus-tainability standpoint, this thesis doc

Objective: To redesign the current assembly process of the Ektorp Sofa from IKEA in order to improve cycle times, quality levels and to reduce, if possible, costs associated with manufacturing, production times and materials. IKEA wants to increase either the productivity or the quality standard of the Ektorp Sofa by simplifying the processes involved in the construc-tion of the sofa and modernizi

We are living in a changing society where businesses need to keep themselves updated and adapt to changing circumstances. Hence, some brands need to repo- sition themselves to survive. The purpose with repositioning is that a brand wants to convey a different identity and therefore create a new image and position in the consumer’s mind. However, one can only control the change of the identity sinc