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Jim family history cvd 2004

Family burden of cardiovascular mortality: risk implications for offspring in a national register linkage study based upon the Malmö Preventive Project Family burden of cardiovascular mortality: risk implications for offspring in a national register linkage study based upon the Malmö Preventive Project P . M . N I L S S O N , J . - Å . N I L S S O N & G . B E R G L U N D Department of Medicine,

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/jim_family_history_cvd_2004.pdf - 2026-05-20

Annual report 2013

Annual Report 2013 Æ N I L O R A C Æ N I L O R A C V MR Q T V V E D A Department of Geology Annual Report 2013 LUND UNIVERSITY Table of Contents Prefect’s Letter Research Highlights Continental Dynamics Evolution of the Biosphere Environmental Dynamics Palaeoecology and Palaeoclimatology Biogeochemical Cycles Applied Geology Glacial Geology Solar and Geomagnetic Dynamics 1 3 6 10 12 15 17 19 22 1

https://www.geology.lu.se/sites/geology.lu.se/files/annual_report_2013.pdf - 2026-05-20

Indigenous Peoples' Right to Land and Natural Resources When Companies Act In Their Traditional Territory: An Enquire of International Human Rights Systems with a Focus on the Inter-American Court of Human Rights and the African Regional System of Human Rights

This thesis approaches how International Human Rights Law is addressing the protection of indigenous peoples’ right to land when States give concessions for companies to act inside indigenous traditional territory. Cases of harmful conducts committed by companies in indigenous territory are continuously happening around the world. Regional systems of human rights protection, through their state-ce

Publication in acta neuropathol

1 3 Acta Neuropathol (2014) 127:283–295 DOI 10.1007/s00401-013-1219-1 CAse RepORt The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast‑derived neurons Mariangela Iovino · Ulrich Pfisterer · Janice L. Holton · Tammaryn Lashley · Robert J. Swingler · Laura Calo · Rebecca Treacy · Tamas Revesz · Malin Parmar · Michel Goedert · Mira

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_acta_neuropathol.pdf - 2026-05-20

Quantitative Proteomics Profiling of Primary Lung Adenocarcinoma Tumors Reveals Functional Perturbations in Tumor Metabolism

In this study, we have analyzed human primary lung adenocarcinoma tumors using global mass spectrometry to elucidate the biological mechanisms behind relapse post surgery. In total, we identified over 3000 proteins with high confidence. Supervised multivariate analysis was used to select 132 proteins separating the prognostic groups. Based on in-depth bioinformatics analysis, we hypothesized that

Temporal development of the humoral immune response to surface antigens of Moraxella catarrhalis in young infants

The primary Moraxella catarrha/is-specific humoral immune response, and its association with nasopharyngeal colonization, was studied in a cohort of infants from birth to 2 years of age. Results indicated that the levels of antigen-specific IgG, IgA and IgM showed extensive inter-individual variability over time, with IgM and IgA levels to all 9 recombinant domains, from 7 different OMPs, being re

Integration of Proteomics and Transcriptomics Data Sets for the Analysis of a Lymphoma B-Cell Line in the Context of the Chromosome-Centric Human Proteome Project

A comprehensive study of the molecular active landscape of human cells can be undertaken to integrate two different but complementary perspectives: transcriptomics, and proteomics. After the genome era, proteomics has emerged as a powerful tool to simultaneously identify and characterize the compendium of thousands of different proteins active in a cell. Thus, the Chromosome-centric Human Proteome

Reconfigurable cell array for concurrent support of multiple radio standards by flexible mapping

This paper presents a flexible architecture suitable for concurrent processing of multiple radio standards. The proposed architecture is based on a coarse-grained reconfigurable cell array, consisting of distinct processing and memory cells. Flexibility of the architecture is demonstrated by performing a coarse time synchronization and fractional frequency offset estimation for multiple OFDM stand

Evaluation of MLH1 I219V Polymorphism in Unrelated South American Individuals Suspected of Having Lynch Syndrome.

Some single-nucleotide polymorphisms are associated with higher risk of colorectal cancer development and are suggested to explain part of the genetic contribution to Lynch syndrome. Aim: To evaluate the mutL homolog 1 (MLH1) I219V polymorphism in 124 unrelated South American individuals suspected of having Lynch syndrome, based on frequency, association with pathogenic MLH1 and mutS homolog 2 (MS

Plasma apolipoprotein M responses to statin and fibrate administration in type 2 diabetes mellitus

Purpose: Plasma apolipoprotein M (apoM) is potentially anti-atherogenic, and has been found to be associated positively with plasma total, LDL and HDL cholesterol in humans. ApoM may, therefore, be intricately related to cholesterol metabolism. Here, we determined whether plasma apoM is affected by statin or fibrate administration in patients with diabetes mellitus. Methods: Fourteen type 2 diabet

Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function

Malaria-induced sepsis is associated with an intense proinflammatory cytokinemia for which the underlying mechanisms are poorly understood. It has been demonstrated that experimental infection of humans with Plasmodium falciparum primes Toll-like receptor (TLR)-mediated proinflammatory responses. Nevertheless, the relevance of this phenomenon during natural infection and, more importantly, the mec

Future RISING experiments at relativistic energies

The proposed experiments for the first RISING (Rare ISotope INvestigations at GSI) campaign will exploit secondary unstable beams at relativistic energies in the range from 100 MeV/u to 400 MeV/u. The RISING spectrometer will be employed for relativistic Coulomb excitation and for high-resolution gamma-spectroscopy experiments after secondary nucleon removal reactions and secondary fragmentation.

New Particle Formation and Growth from Dimethyl Sulfide Oxidation by Hydroxyl Radicals

Dimethyl sulfide (DMS) is produced by plankton in oceans and constitutes the largest natural emission of sulfur to the atmosphere. In this work, we examine new particle formation from the primary pathway of oxidation of gas-phase DMS by OH radicals. We particularly focus on particle growth and mass yield as studied experimentally under dry conditions using the atmospheric simulation chamber AURA.

Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells

Changes in gene regulation and expression govern orderly transitions from hematopoietic stem cells to terminally differentiated blood cell types. These transitions are disrupted during leukemic transformation, but knowledge of the gene regulatory changes underpinning this process is elusive. We hypothesized that identifying core gene regulatory networks in healthy hematopoietic and leukemic cells

A pan-European, multipopulation assessment of migratory connectivity in a near-threatened migrant bird

Aim: The extent to which individuals from different breeding populations mix throughout the non-breeding season (i.e. 'migratory connectivity') has important consequences for population dynamics and conservation. Given recent declines of long-distance migrant birds, multipopulation tracking studies are crucial in order to assess the strength of migratory connectivity and to identify key sites en r

Automating algebraic proof systems is NP-hard

We show that algebraic proofs are hard to find: Given an unsatisfiable CNF formula F, it is NP-hard to find a refutation of F in the Nullstellensatz, Polynomial Calculus, or Sherali-Adams proof systems in time polynomial in the size of the shortest such refutation. Our work extends, and gives a simplified proof of, the recent breakthrough of Atserias and Müller (JACM 2020) that established an anal

Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation : An international multicenter study

Mucopolysaccharidosis type I-Hurler syndrome (MPS-IH) is a lysosomal storage disease characterized by multisystem morbidity and death in early childhood. Although hematopoietic cell transplantation (HCT) has been performed in these patients for more than 30 years, large studies on the long-term outcome of patients with MPS-IH after HCT are lacking. The goal of this international study was to ident

Hospital admission for neurologic disorders among 5-year survivors of noncentral nervous system tumors in childhood : A cohort study within the Adult Life after Childhood Cancer in Scandinavia study

Large, comprehensive studies of the risk for neurologic disorders among long-term survivors of noncentral nervous system (CNS) childhood cancers are lacking. Thus, the aim of our study was to assess the lifetime risk of Nordic non-CNS childhood cancer survivors for neurologic disorders. We identified 15,967 5-year survivors of non-CNS childhood cancer diagnosed in Denmark, Iceland, Finland and Swe

Te incorporation and activation as n-type dopant in self-catalyzed GaAs nanowires

Dopant atoms can be incorporated into nanowires either via the vapor-liquid-solid mechanism through the catalyst droplet or by the vapor-solid growth on the sidewalls. Si is a typical n-type dopant for GaAs, but in nanowires it often suffers from a strongly amphoteric nature in the vapor-liquid-solid process. This issue can be avoided by using Te, which is a promising but less common alternative f