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Gaia Early Data Release 3 : Parallax bias versus magnitude, colour, and position

Context. Gaia Early Data Release 3 (Gaia EDR3) gives trigonometric parallaxes for nearly 1.5 billion sources. Inspection of the EDR3 data for sources identified as quasars reveals that their parallaxes are biased, that is, they are systematically offset from the expected distribution around zero, by a few tens of microarcseconds. Aims. We attempt to map the main dependences of the parallax bias in

Public Key Compression and Fast Polynomial Multiplication for NTRU using the Corrected Hybridized NTT-Karatsuba Method

NTRU is a lattice-based public-key cryptosystem that has been selected as one of the Round III finalists at the NIST Post-Quantum Cryptography Standardization. Compressing the key sizes to increase efficiency has been a long-standing open question for lattice-based cryptosystems. In this paper we provide a solution to three seemingly opposite demands for NTRU cryptosystem: compress the key size, i

AI i offentlig sektor : Från etiska riktlinjer till lagstiftning

Användningen av artificiell intelligens (AI), det vill säga en rad primärt databeroende metoder och teknologier för bland annat prediktion och automation, tycks bidra till en omvälvande period i den offentliga förvaltningen. Detta skifte föranleder ett styrningsbehov, ofta kopplat till tillitsfrågor, vilket i en internationell kontext inte minst syns i en stor mängd etiska riktlinjer och principie

Nivestam et al 2020

Factors associated with good health among older persons who received a preventive home visit: a cross-sectional study RESEARCH ARTICLE Open Access Factors associated with good health among older persons who received a preventive home visit: a cross-sectional study Anna Nivestam1,2* , Albert Westergren1,2 , Pia Petersson1 and Maria Haak1,2 Abstract Background: The ageing population is increasing wo

https://www.sweah.lu.se/en/sites/sweah.lu.se.en/files/nivestam_et_al_2020.pdf - 2026-05-15

Methods comparison report 2017

Methods comparison report 2017.pdf IN COLLABORATION WITH GRADUATE SCHOOL Annika Hughes PhD, Graduate School, Faculty of Social Sciences & Christopher Swader (corresponding author) Associate Senior Lecturer, Graduate School & Department of Sociology, Faculty of Social Sciences christopher.swader@soc.lu.se COMPARISON REPORT Lund University Malmö University College Uppsala University University of Go

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/methods_comparison_report_2017.pdf - 2026-05-15

Combinatorial DNMTs and EZH2 inhibition reprograms the H3K27me3 and DNAme-mediated onco-epigenome to suppress multiple myeloma proliferation

Comprehensive epigenomic studies in multiple myeloma (MM) that unravel the connections between major epigenetic regulators, their intertwined collaboration and the potential of combinatorial targeting remain limited. Utilizing ChIP-seq, ATAC-seq, RNA-seq, and DNA methylation (DNAme) data, we generated whole-genome chromatin annotations from normal plasma cells and MM patients, revealing epigenomic

N=50 Core Excited States Studied in the 96Pd Nucleus

The four-proton hole Pd-96 neighbor of the doubly-magic Sn-100 nucleus was studied in-beam, using a fusion-evaporation reaction of a Ni-58 beam on a Sc-45 target. States of Pd-96 were established up to an excitation energy of 9707 keV. A core-excited odd-parity isomer with T-1/2 = 37.7(1.1) ns was identified. Shell model calculations were performed in four different model spaces. Even-parity state

Safety Management Systems in micro and small air operators: mission possible?

This thesis explores the rationality, completeness and functioning of Safety Management Systems (SMS) amongst micro- and small-sized air operators in business aviation. In the absence of thorough literature in this sector of aviation, a survey of prior research on OHS(MS) and on non-aviation micro/small enterprises (MSE) provided a collection of factors contributing to their safety performance. Us

Enlarged cavum septum pellucidum as a neuroimaging signature of head impact exposure

Cavum septum pellucidum (CSP) is commonly observed upon neuroimaging examination in individuals exposed to repetitive head impacts (RHI) and post-mortem in cases with chronic traumatic encephalopathy. Consequently, CSP has been proposed as a potential biomarker for RHI-related neurodegeneration, yet prevalence estimates of CSP across other neurodegenerative diseases and its clinical implications a

Nasogastric tube after oesophagectomy and risk of anastomotic leak : a Nordic, multicentre, open-label, randomised, controlled, non-inferiority trial

BACKGROUND: Oesophagectomy, a corner stone in curative treatment of oesophageal cancer, is a complex procedure with high complication rates. Postoperative gastric tube decompression is debated and some centres are abandoning routine nasogastric (NG) tube use. We hypothesised that postoperative NG tube removal is non-inferior to five days of NG tube decompression, with regard to the risk of anastom

Driving to Learn: use of the Assessment of Learning Power mobility 2.0 tool to monitor and guide the learning process of using electric toy cars as mobility aids in early intervention for young children with motor disabilities : Clinical problem Assessment of learning power mobility tool: evaluation and intervention strategies

Mini-Symposium Duration: 55 Minutes Contemporary evidence-based models support the early use of electric cars as mobility aids in children with motor disabilities. Monitoring how each child learns to interact with the car, and the learning progression is the key to adjusting the intervention strategies. The ALP 2.0 tool is a qualitative assessment that offers therapists and families a classificati

Empirically informed symptom severity cutoffs for body dysmorphic disorder

BackgroundSymptom severity cutoffs for body dysmorphic disorder (BDD) are lacking, hindering communication between professionals and with the patient community.MethodWe pooled data from 11 clinical trials or high-quality cohort studies from specialist clinics, totaling 804 individuals with BDD (80 % girls/women, 67 % adults). All participants had baseline scores on the adult or adolescent versions

Ligand-independent G protein-coupled estrogen receptor/G protein-coupled receptor 30 activity : Lack of receptor-dependent effects of G-1 and 17b-estradiol

G protein-coupled receptor 30 (GPR30) is a membrane receptor reported to bind 17b-estradiol (E2) and mediate rapid nongenomic estrogen responses, hence also named G protein-coupled estrogen receptor. G-1 is a proposed GPR30-specific agonist that has been used to implicate the receptor in several pathophysiological events. However, controversy surrounds the role of GPR30 in G-1 and E2 responses. We

MET Expression and Cancer Stem Cell Networks Impact Outcome in High-Grade Serous Ovarian Cancer

Overexpression of the receptor tyrosine kinase MET has been linked to poor survival in several cancer types, and MET has been suggested to interact with stem cell networks. In vitro studies have further suggested a possible benefit of a combined treatment using PARP and MET inhibitors. We used a tissue microarray (TMA) with 130 samples of advanced-stage high-grade serous fallopian tube/ovarian can

Integration of remote sensing and Mexican water quality monitoring system using an extreme learning machine

Remote Sensing, as a driver for water management decisions, needs further integration with monitoring water quality programs, especially in developing countries. Moreover, usage of remote sensing approaches has not been broadly applied in monitoring routines. Therefore, it is necessary to assess the efficacy of available sensors to complement the often limited field measurements from such programs

Neonatal Bacille Calmette-Guérin vaccination and tuberculin skin test reactions at 2- and 6-months : Effects on mortality up to 1 year of age

Background: In randomized trials, Bacille Calmette-Guérin (BCG) vaccine has been associated with reduced all-cause mortality. BCG-induced Tuberculin Skin Test (TST) reactions have also been associated with reduced all-cause mortality. We aimed to assess the association between TST responses and subsequent mortality in three birth cohorts and conducted a meta-analysis of existing studies. Methods:

EMA Review of Daratumumab (Darzalex) for the Treatment of Adult Patients Newly Diagnosed with Multiple Myeloma

The use of daratumumab in combination with established regimens for the treatment of newly diagnosed multiple myeloma has recently been authorized by the European Medicines Agency based on results from three separate phase III randomized, active controlled, open-label studies that have confirmed enhanced efficacy and tolerability in both transplant-ineligible (MMY3008 and MMY3007) and transplant-e

Therapeutic Recommendations for the Management of Older Adult Patients with Sjögren’s Syndrome

Primary Sjögren’s syndrome (SjS) is a systemic autoimmune disease most commonly diagnosed in middle-aged women. Although the disease can occur at all ages, it is diagnosed between 30 and 60 years of age in two-thirds of patients. In more than 20% of cases, the people are older than 65 years. In this review, we focus on the therapeutic management of primary SjS in older patients, following the rece

Pathological drivers of neurodegeneration in suspected non-Alzheimer’s disease pathophysiology

Background: Little is known about the heterogeneous etiology of suspected non-Alzheimer’s pathophysiology (SNAP), a group of subjects with neurodegeneration in the absence of β-amyloid. Using antemortem MRI and pathological data, we investigated the etiology of SNAP and the association of neurodegenerative pathologies with structural medial temporal lobe (MTL) measures in β-amyloid-negative subjec

Bark of passiflora edulis treatment stimulates antioxidant capacity, and reduces dyslipidemia and body fat in db/db mice

Obesity is considered an important risk factor for several disorders, such as diabetes mellitus, systemic arterial hypertension, dyslipidemia, and atherosclerosis, which are associated with inflammation and oxidative stress as a trigger factor. Passiflora edulis contains important bioactive compounds, such as phenolics, carotenoids, vitamin C, and polyamines in pulp, leaves, seeds, and bark. Aim: