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UNLABELLED: Persistent CB1 cannabinoid receptor activity limits neurotransmitter release at various synapses throughout the brain. However, it is not fully understood how constitutively active CB1 receptors, tonic endocannabinoid signaling, and its regulation by multiple serine hydrolases contribute to the synapse-specific calibration of neurotransmitter release probability. To address this questi

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Att ersätta ändliga resurser med förnybara alternativ är en av mänsklighetens största utmaningar i modern tid. Utsläpp av växthusgaser orsakade av mänsklig civilisation behöver minska, och nya forskningsbaserade lösningar är nödvändiga för att åstadkomma långsiktigt hållbar tillväxt. I denna omställning kan biomassa från växter spela en viktig roll. Växtbiomassa består mestadels av socker som sittβ-Mannanases are a major type of enzyme involved in the hydrolysis and modification of β-mannans, a hemicellulose present in high amounts in e.g. softwoods such as spruce. The β-mannanases studied in this thesis belong to glycoside hydrolase (GH) families GH5 and GH26. In addition to hydrolysis, some β-mannanases can also catalyze transglycosylation whereby another molecule (acceptor) is transferr

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Background In pediatric patients, computed tomography (CT) is important in the medical chain of diagnosing and monitoring various diseases. Because children are more radiosensitive than adults, they require minimal radiation exposure. One way to achieve this goal is to implement new technical solutions, like iterative reconstruction. Purpose To evaluate the potential of a new, iterative, model-basBackgroundIn pediatric patients, computed tomography (CT) is important in the medical chain of diagnosing and monitoring various diseases. Because children are more radiosensitive than adults, they require minimal radiation exposure. One way to achieve this goal is to implement new technical solutions, like iterative reconstruction.PurposeTo evaluate the potential of a new, iterative, model-based

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The number of traffic-related fatalities has dropped significantly in the last few decades, but the trend in fire safety, albeit positive, show a less rapid improvement. One reason could be the introduction of the Euro-NCAP-system in traffic safety which has been instrumental in promoting innovation in the field. In this report, a first version of a similar system for smoke alarms, arguably a most

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Sweden was one of the first countries in the world to declare that it had a feminist government, following years of high rankings on global gender equality indexes and a relatively stable image of Sweden as a gender equality leader. However, the declaration has been accompanied by scholarly inquiry defying claims connected to Swedish feminist governance, often challenging its transformative capaci

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This paper tests if structural reforms in the presence of fiscal adjustments have growth enhancing effects. We do this by using two well established measures from the previous literature to identify periods of fiscal adjustments. These measures are the outcome based and the action based approach. As a proxy for structural reforms this paper relies on changes in institutional quality measured by th

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The possibility of trade-offs in road tunnel design incorporating suppression has been evaluated. Different tunnel configurations and ventilation conditions considered to identify potential trade-offs, offering options of design alternatives for future substantial cost-benefit estimates. Suppression systems are regularly used in Australia and Japan. The interest regarding suppression systems in tu

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Problem definition Even though a great deal of research have been done exploring the ERP field, companies still have a hard time determining and obtaining the full potential scope of benefits that comes with a fully working ERP system. Implementing an ERP system is like changing a heart while the patient still is running. It is therefore hard to measure the benefits and the improved efficiencies,

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Self-compassion has not yet been studied in younger children. The aim of this study was to explore self-compassion in children between 10-13 years of age and examine how self-compassion is related to well-being and social perspective-taking. In addition we wanted to explore possible age or sex differences in self-compassion. The participants consisted of 228 children from two elementary schools in

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《在幽昏中顯影:港中對話中國獨立紀錄片2014-2020》一書以導演、學者、觀眾對話的形式,討論了中國獨立紀錄片研究會(香港)2014至2020年期間展映、製片、發行的獨立電影。我們從中選擇了記錄較為完整的“叛逆中國”、“飛越瘋人院”、“情慾中國”三個展映單元的獨立紀錄片討論,以及針對夾邊溝右派農場倖存者記憶、維吾爾和新疆議題、三自教會、地下知識分子、前政府高官、工人抗爭等18部影片的映後交流文本或者導演訪談文本,形成本書“性、性別與女性主體”、“權利與政治”、“歷史與記憶”、“放逐與流亡”四個部分的主要內容。本書還收入研究會參與製片的《喊叫與耳語》首映對談,曾金燕對艾未未在跨國視野(流亡處境)下關於藝術(如《人流》)、社會行動和審查的兩次訪談,曾金燕對應亮半自傳劇情片《自由行》的訪談、曾金燕對艾曉明關於性別、紀錄片和社會行動的訪談、曾金燕與王月眉關於在香港八年“邊緣”經驗的筆談。額外收入

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This article offers a reconsideration of religious mobilisation in the inter- and post-war periods. It focuses on how the Church of Sweden gradually altered its catechetical activities aimed at children to meet changing needs. Built on a range of statistical sources, this article calls for a reconsideration of the ways in which larger Protestant denominations adjusted to meet declining religious pThis article offers a reconsideration of religious mobilisation in the inter- and postwar periods. It focuses on how the Church of Sweden gradually altered its catechetical activities aimed at children to meet changing needs. Built on a range of statistical sources, this article calls for a reconsideration of the ways in which larger Protestant denominations adjusted to meet declining religious pr

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A range of third-sector organizations, among them diaconal actors, contributes actively to the welfare mix in the Nordic countries. The independence of these actors is in constant tension with the fact that the organizations are dependent on resources from the surrounding society. Norms and rules influence nonprofit organizations to adopt practices that change the organization, in the direction ofA range of third-sector organizations, among them diaconal actors, contributes actively to thewelfare mix in the Nordic countries. The independence of these actors is in constant tension with thefact that the organizations are dependent on resources from the surrounding society. Norms andrules influence nonprofit organizations to adopt practices that change the organization, in thedirection of an

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The course Global Environmental Governance Today–Actors, Institutions, Complexity is an in- terdisciplinary PhD course and has welcomed participants from a wide range of disciplinary backgrounds with equally varied prior knowledge on environmental governance practices and theories. Thus, every year, participants include students who are not familiar with international relations theories such as re

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The script we are presenting below is one of four different scenarios from Violence & Learning by Henrik Bromander and John Hanse, which was performed at the International Brecht Society’s Symposium in Oxford in June 2016. The learning play Violence & Learning has been developed and performed in the context of left-wing activism in Sweden. The different variants of the play have partly bee

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In 2007 more than a quarter (26%) of the South African adult population was functionally illiterate. As a result many non-profit organisations (NPOs) in South Africa strive to raise adult literacy levels. Adult illiteracy leads to problems such as, amongst others, high levels of unemployment, poverty and crime.Most NPOs do not practice strategic communication management to build strong, lasting an