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Novel peptide ligand with high binding capacity for antibody purification

Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography

Immune responses following meningococcal serogroups A, C, Y and W polysaccharide vaccination in C2-deficient persons: Evidence for increased levels of serum bactericidal antibodies.

Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal

Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient

γ-globulins prepared from sera of multiparous women bind anti-HLA antibodies and inhibit an established in vivo human alloimmune response

It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar

TFPI-2 protects against gram-negative bacterial infection

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

Disputationer 2005

Vilhelm PerssonRättsliga ramar för gränsöverskridande samarbeteFörvaltningsmyndigheters internationella arbetsförhållandenDatum för disputation: lördagen den 10 december 2005Fakultetsopponent: docent Ulrik von Essen, Stockholm universitet, SverigeÄmne: offentlig rättAbstractSvenska myndigheter behöver ibland samarbeta med utländska myndigheter, till exempel i ärenden som rör personer, föremål elle

https://www.jur.lu.se/forskning/disputationer/disputationer-2005 - 2026-06-05

Personality and information use in fish: bolder crucian carps learn faster

Popular science summary: Bolder the brighter – personality affects learning performance in crucian carp Just as humans, many animals have a personality. For example some individuals are more prone to take risks – they are bold, while others prefer to play it safe – being shy. Bold animals increase their risk of being attacked by a predator but may also receive higher gains by being first to a foAbstract Gathering information about the environment is crucial to living organisms as it makes up the foundation upon which decisions are made. In a diverse environment a huge amount of information sources arise. An individual can choose to follow other’s decision (social information use) or to gather its’ own information. Which sources are used and how well they are perceived vary between indi

Samband mellan nedsatt kognitiv förmåga och försämrad prognos vid hjärtsvikt – Vetenskap och Hälsa

Samband mellan nedsatt kognitiv förmåga och försämrad prognos vid hjärtsvikt – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Samband mellan nedsatt kognitiv förmåga och försämrad prognos vid hjärtsvikt 2020-08-26 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommi

https://www.vetenskaphalsa.se/samband-mellan-nedsatt-kognitiv-formaga-och-forsamrad-prognos-vid-hjartsvikt/ - 2026-06-07

Komnu-en-pdf

Kommunikation i naturvetenskaplig utbildning RAPPORT | EQ11-PROJEKT | LUNDS UNIVERSITET SUSANNE PELGER & SARA SANTESSON 3KOMMUNIKATION I NATURVETENSKAPLIG UTBILDNING Förord Denna rapport är resultatet av EQ11-projektet Kommunikation i Naturvetenskaplig Utbildning (KomNU), som har genomförts vid Lunds universitets naturvetenskapliga fakultet. Det är många personer som har bidragit till att göra Kom

https://www.naturvetenskap.lu.se/sites/naturvetenskap.lu.se/files/2021-05/komnu-en-pdf.pdf - 2026-06-06

Pi-gp.fd08poster

Poster Fechner Day 2008 Introduction Fechner (1801-1887) first discovered that when two stimuli are presented for comparison people systematically overestimate the magnitude of one stimulus and underestimate the magnitude of the other; termed, time-order effect (TOE) for stimuli separated by a time interval, and space-order effect (SOE) for stimuli separated spatially. Asymmetries in sensory discr

https://www.psy.lu.se/en/sites/psy.lu.se.en/files/pi-gp.fd08poster.pdf - 2026-06-06

”Jag bryr mig inte om jag får artros när jag är 35 …” – Vetenskap och Hälsa

”Jag bryr mig inte om jag får artros när jag är 35 …” – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök ”Jag bryr mig inte om jag får artros när jag är 35 …” 2013-09-03 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. ”Jag bryr mig inte om jag får artros när ja

https://www.vetenskaphalsa.se/jag-bryr-mig-inte-om-jag-far-artros-nar-jag-ar-35/ - 2026-06-05

Ljumske och höft kollas med 5-sekunderstest – Vetenskap och Hälsa

Ljumske och höft kollas med 5-sekunderstest – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Ljumske och höft kollas med 5-sekunderstest 2019-03-22 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Fem sekunder. Det kan vara tillräckligt för att uppskatta statu

https://www.vetenskaphalsa.se/ljumske-och-hoft-kollas-med-5-sekunderstest/ - 2026-06-05

Our research

Research Areas The research area of clinical and epidemiological research in cognition aims to study risk factors of reduced cognitive ability particularly vascular mechanisms. Another aim entails taking care of already reduced cognitive ability. Several clinical and longitudinal studies have involved mechanisms of interrupted autoregulation of cerebral blood flow, correlation between hypertension

https://www.geriatrik.lu.se/geriatrics/our-research - 2026-06-05