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The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously successfully applied in rabbits, aiming for induction of post-streptococcal glomerulonephritis (PSGN). To induce the nephropathy, we used two Streptococcus pyogenes strains of M4 and M60 serotypes which showed differential IgA-binding capacity me

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

GAD65 autoantibodies (GAD65Ab) are highly prevalent in type 1 diabetes, but their functional role in the pathogenesis of the disease and their relationship to T-cell reactivity to GAD65 is still unclear. We tested the hypothesis that GAD65Ab modulate presentation of GAD65 to T-cells. T-cell hybridoma T33.1, which recognizes the GAD65 274-286 epitope in the context of HLA-DRB1*0401, was incubated w

The aim of this dissertation is to investigate a number of U.S. avant-garde films using Deleuzian film-philosophy in order to describe their thought. I develop the taxonomy of cinematic images created by the French philosopher Gilles Deleuze by introducing a new type of image. The notion of the sobjective image I conceptualize points to the immanent semiosis that characterizes certain films. The s

Supersonic combustion is a critical area of research for advancing high-speed flight technologies, particularly for the development of scramjet engines for hypersonic vehicles. This study employs Finite Rate Chemistry (FRC) Large Eddy Simulation (LES) together with different experimental techniques to study the supersonic flow and thermochemical processes in the Small Scale Flight Experiment (SSFE

Understanding wireless channels is crucial for the design of wireless systems. For mobile communication, sounders and antenna arrays with short measurement times are required to simultaneously capture the dynamic and spatial channel characteristics. Switched antenna arrays are an attractive option that can overcome the high cost of real arrays and the long measurement times of virtual arrays. Opti

From the point of view of semiotics, the essential contribution of John Deely consists in having made us all aware of the richness of the Scholastic heritage, and to have explained it to us latter-day semioticians. Even for those, who, like the present author, think that semiotics was alive and well between the dawn of the Latin Age, and the rediscovery of Scholastic realism by Peirce, the notions

This thesis investigates the adoption of artificial intelligence (AI) solutions among architects in Sweden. Architects are currently experiencing headwinds and decreased demands for their services as increasing interest rates and a weak economy have contributed to a decline in construction activity. Simultaneously, advancements in AI have introduced a range of innovative technologies to the field

China’s financial actions along the BRI network has sparked a lot of controversies, one of these being the alleged usage of Debt Trap Diplomacy (DTD) in order to gain access to resources through debt relief that they otherwise would not be able to reach through traditional means. DTD practices can be considered part of the International Political Economy’s ‘blind spots’ due to their complexity and

In the wake of well-known instances of corporate misconduct – for example Enron in the U.S., and Skandia in Sweden – consumers ask for more transparent corporate brand practices to make corporate brands trustworthy. However, potentially, consumers who put their trust in brands may be sacrificing some of their own control, thus weakening themselves in the trusting relationship. The aim of this book