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The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structures, called exosomes, microvesicles, microparticles, ectosomes, oncosomes, apoptotic bodies, and many other names. However, specific issues arise when w

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In academic work on modern British poetry, there is a tacit assumption that any poet belonging to the first rank must needs be a “Modernist”. Consequently, scholars and critics are keen to have poets they admire fit in under the “Modernism” umbrella. That desire has led to an extension of the concept–always notoriously hard to define–to the point of meaninglessness. Proceeding from a conviction th

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In this study doctoral students in psychology and social anthropology/ethnology were interviewed as to their selection of research problem for their Ph.D. thesis. From the perspective of activity theory it is suggested that the research problem can profitably be seen as the object of activity in research. Graduate students’ selection of a research problem was analyzed as a process occurring over t

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By studying the responses to the last expulsion for "apostasy" from the Swedish National Church in 1858, this article examines how an international Protestant identity was constructed in mid-nineteenth-century Europe. It is the argument of this study that a comprehensive identity - including both evangelicals and theological progressives - could be built around the notion of religious liberty. The

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Assessment of the fire behaviour of sandwich panels is continuously under discussion. The fire behaviour of these panels is a combination of material characteristics such as the core material and mechanical behaviour of the panels such as joints, dilations etc. The use of small or intermediate scale tests can be questioned for such types of products. Within the proposed European product standard

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OBJECTIVE: To investigate whether left atrial appendage outflow velocity alone or in relation to left atrial diameter is a superior predictor of sinus rhythm maintenance after cardioversion compared with traditional clinical or echocardiography parameters. DESIGN: Sixty-two patients with their first episode of atrial fibrillation were examined using echocardiography before DC-cardioversion. At one

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Objective: Systemic lupus erythematosus (SLE) is a complex disease with variable presentations, course and prognosis. We sought to develop evidence-based recommendations addressing the major issues in the management of SLE. Methods: The EULAR Task Force on SLE comprised 19 specialists and a clinical epidemiologist. Key questions for the management of SLE were compiled using the Delphi technique. A

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Background Starting in the 1960s, a broad-based patients’ rights movement began to question doctors’ paternalism and to demand disclosure of medical information, informed consent, and active participation by the individual in personal health care. According to scholars, these changes contributed to downplay the biomedical approach in favor of a more patient-oriented perspective. The Swedish non-p

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Context. In 1992 we began a precision radial velocity survey for planets around solar-like stars with the Coude Echelle Spectrograph and the Long Camera (CES LC) at the 1.4m telescope in La Silla (Chile) resulting in the discovery of the planet iota Hor b. We have continued the survey with the upgraded CES Very Long Camera (VLC) and the HARPS spectrographs, both at the 3.6m telescope, until 2007.

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Background: Clinical trial participants may be temporarily absent or withdraw from trials, leading to missing data. In intention-to-treat (ITT) analyses, several approaches are used for handling the missing information - complete case (CC) analysis, mixed-effects model (MM) analysis, last observation carried forward (LOCF) and multiple imputation (MI). This report discusses the consequences of app

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Aims. We present line identifications in the 1700 to 10 400 angstrom region for the Weigelt blobs B and D, located 0.'' 1 to 0 ''.3 NNW of Eta Carinae. The aim of this work is to characterize the behavior of these luminous, dense gas blobs in response to the broad highstate and the short low-state of. Carinae during its 5.54-year spectroscopic period. Methods. The spectra were recorded in a low st

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Inom svensk arbetsrätt är (SFS 1982:80) lagen om anställningsskydd den centrala lagstiftningen som reglerar anställningsform och hur en uppsägning får ske. Arbetstagaren har turordningsreglerna i 22§ Lag om anställningsskydd som skydd och i det anciennitetsprincipen (senioritetsprincipen), då arbetsgivaren anfört arbetsbrist inom verksamheten som uppsägningsskäl. Turordningsreglerna har varit In Swedish labor law (SFS 1982: 80), the Employment Protection Act is the central legislation that regulates the form of employment and how a termination may take place. The employee has the rules of priority in section 22 of the Employment Protection Act as protection and in the seniority principle, when the employer cites lack of work as a reason for termination. The rules of priority have been

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Den ryska invasionen av Ukraina har orsakat ofattbart mänskligt lidande och har destabiliserat den europeiska säkerhetsordningen. I gengäld har världsledare och internationella organisationer krävt att den ryska aggressionen beivras. Den rättsvetenskapliga debatten om lämpliga åtgärder för att säkerställa straffrättsligt ansvar för aggressionsbrottet har emellertid uppvisat stor oenighet bland forThe Russian invasion of Ukraine has brought immense suffering to the Ukrainian people and has destabilised the European security order. In response, world leaders and international organisations have called for the prosecution of the Russian aggression. However, the scholarly debate on the appropriate measures to ensure criminal accountability for the crime of aggression has demonstrated widesprea

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Climate-related security risks (CRSR) have risen on the foreign policy agenda of the European Union (EU). As climate change accelerates, its impacts exacerbate existing social, economic, and environmental challenges within and between communities and increase the likelihood of states experiencing humanitarian crises and conflict. These so-called climate-related security risks (CRSR), or climate-se

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Digitalisation and its effect on the circular economy have been a major debate. Thus, this study investigates the possible contributions of Digital Business Models (DBMs) toward the Circular Economy (CE) by utilising circular economy core values through its multiple dimensions. Following a qualitative approach, semi-structured interviews were conducted with eight participants in the retail sector.