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OBJECTIVE : To identify predictors of later study withdrawal among participants active in The Environmental Determinants of Diabetes in the Young (TEDDY) for 1 year. METHODS : Multiple logistic regression was used to discriminate 3,042 children active in TEDDY for the first 3 years from 432 children who withdrew in Years 2 or 3. Predictor variables were tested in blocks-demographic, maternal lifes

BACKGROUND: The use of global gene expression profiling is a well established approach to understand biological processes. One of the major goals of these investigations is to identify sets of genes with similar expression patterns. Such gene signatures may be very informative and reveal new aspects of particular biological processes. A logical and systematic next step is to reduce the identified

To comprehensively characterize microRNA (miRNA) expression in breast cancer, we performed the first extensive next-generation sequencing expression analysis of this disease. We sequenced small RNA from tumors with paired samples of normal and tumor-adjacent breast tissue. Our results indicate that tumor identity is achieved mainly by variation in the expression levels of a common set of miRNAs ra

The scalar polarizability constant [alpha]0 for the 10, 11 2S1/2 and 9 2D5/2 states of 133Cs was measured i Stark effect experiment on a collimated atomic beam. The states were reached by a two-step excitation procedure involving a single-mode dye laser.

Objective. In the European Association of Urology guidelines on prostate cancer an extended pelvic lymphadenectomy (ePLND) is now recommended, instead of a dissection limited to the obturator fossae (lPLND). This recommendation relies on studies reporting that metastatic disease is identified twice as often with ePLND as with lPLND, with only moderately increased complications. However, these stud

A search for the pair production of heavy leptons as predicted by the type-III seesaw mechanism is presented. The search uses proton–proton collision data at a centre-of-mass energy of 13 TeV, corresponding to 139fb-1 of integrated luminosity recorded by the ATLAS detector during Run 2 of the Large Hadron Collider. The analysis focuses on the final state with two light leptons (electrons or muons)

Purpose: In the last decade, the research community has focused on defining reliable biomarkers for the early detection of Alzheimer’s disease (AD) pathology. In 2017, the Geneva AD Biomarker Roadmap Initiative adapted a framework for the systematic validation of oncological biomarkers to cerebrospinal fluid (CSF) AD biomarkers—encompassing the 42 amino-acid isoform of amyloid-β (Aβ42), phosphoryl

In this paper we study Fourier multiplers on radially weighted Bergman Hilbert spaces of analytic functions in the unit disc. We relate the Berezin transform of such a Fourier multipler to a certain expansion formula in terms of the associated shift operator. We also show that the possibility of a specific operator formula of this type considered recently by Louhichi, Olofsson and Wennman implies

In this thesis, I compare the economic development between one democracy, India, and one autocracy, China. The idea is to see whether democracy has anything to do with economic development in terms of growth and welfare. To my disappointment, I have found that democracy does not have a big impact on economic development. Instead, it seems that the economical development depends on the economical p

Commercial sexual exploitation of Children and Adolescents (CSEC) is an increasing problem all over the world and especially in developing countries with growing tourist industries. In these countries CSEC and Child Sex Tourism have become two often closely connected problems. In Costa Rica there are many NGOs and governmental institutions working with these problems through prevention, attention

To deal with the problems resulting from the current unsustainable pattern of resource utilization, the material life cycle of plastics should be extended. Extended producer responsibility (EPR) has been increasingly adopted as a strategy to redirect the material flow, but its contributions to the market development of recycled plastics have not been well researched. Norway is one of the countrie

The role of environmental permits as a driver for environmental improvements has been a topic of debate for a while. Many permitting regulations were designed in the 1970's and have not been updated since then. Consequently, they have acted mostly as a driver for the adoption of pollution control technologies. Some experts now see that appropriately designed and implemented environmental permi

Populärvetenskaplig sammanfattning: Mer än två miljarder människor, mestadels i utvecklingsländer, saknar tillgång till moderna energikällor eller elektricitet. Behovet av rena, effektiva, pålitliga och ekonomiskt överkomliga energitjänster är en viktig fråga i utvecklingsländer, särskilt för landsbygden, där merparten av befolkningen bor. Förnyelsebara energikällor i form av småskaliga vattenkrafOver 2 billion people, mostly in developing countries, have no access to modern fuels or electricity. The necessity of clean, efficient, reliable and affordable energy services is a crucial issue in developing countries, especially in the context of rural areas where the majority of the people lives. Renewable energy sources in shape of small-scale hydropower systems are a complement or alternativ

If one were to study Management Consultancy, they could be spoilt for choices on what to research on. Bombarded by several images of imperviousness, merky business practices , shady deals, compromise, self service, competitive morality and many other forms of euphemisms, the researchers, would see these notions, appear loud and resplendent, especially when, ‘seen through’ client consultant relatio

It is often a challenge for a child to communicate their pain, and their possibilities to do so should be strengthened in healthcare settings. Digital self-assessment provides a potential solution for person-centered care in pain management and promotes child participation when a child is ill. A child's perception of pain assessment differs when it is assessed using digital or analog formats. As w

BACKGROUND AND PURPOSEAcquiring and interpreting quantitative myelin-specific MRI data at an individual level is challenging because of technical difficulties and natural myelin variation in the population. To overcome these challenges, we used multiecho T2 myelin water imaging (MWI) to create T2 metric healthy population atlases that depict the mean and variation of myelin water fraction (MWF), a

Migration has a global impact, but it also intersects with local and nationalissues. In 2020, 281 million people lived outside their country of birth or citizenship, according to the United Nations Global Migration Database. The number of persons displaced across international borders is increasing due to conflict, persecution, and violence. Most of the world’s refugees and asylum seekers live i