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Children with cancer experience recurring hospitalizations and isolation during treatment, which affect their school attendance. This study explores experiences of children with cancer, their classmates, and teachers with using the telepresence robot as a learning mediator in the hybrid classroom during treatment periods. 31 children with cancer (aged 7–17 years), 30 teachers, and 118 classmates p
BACKGROUND: Behavioural therapy for tics is difficult to access, and little is known about its effectiveness when delivered online.OBJECTIVE: To investigate the clinical and cost-effectiveness of an online-delivered, therapist- and parent-supported therapy for young people with tic disorders.DESIGN: Single-blind, parallel-group, randomised controlled trial, with 3-month (primary end point) and 6-m
Differential and double-differential distributions of kinematic variables of leptons from decays of top-quark pairs (tt¯) are measured using the full LHC Run 2 data sample collected with the ATLAS detector. The data were collected at a pp collision energy of s = 13 TeV and correspond to an integrated luminosity of 140 fb −1. The measurements use events containing an oppositely charged eμ pair and
Background - Correct blood group typing is the cornerstone of transfusion medicine. In patients whose gastrointestinal wall is compromised, bacterial enzymes can cause deacetylation of blood group A, converting N-acetylgalactosamine to galactosamine, which resembles the B-defining galactose. This acquired B (acqB) phenomenon, first described 1959, can lead to blood grouping errors. Herein, we expl
Introduction: Commissioning, calibration, and quality control procedures for nuclear medicine imaging systems are typically performed using hollow containers filled with radionuclide solutions. This leads to multiple sources of uncertainty, many of which can be overcome by using traceable, sealed, long-lived surrogate sources containing a radionuclide of comparable energies and emission probabilit
Chest computed tomography (CT) imaging with the use of an artificial intelligence (AI) analysis program has been helpful for the rapid evaluation of large numbers of patients during the COVID-19 pandemic. We have previously demonstrated that adults with COVID-19 infection with high-risk obstructive sleep apnea (OSA) have poorer clinical outcomes than COVID-19 patients with low-risk OSA. In the cur
BACKGROUND: There are few data on outcomes after reintervention for persistent or recurrent primary hyperparathyroidism (PHPT). The authors hypothesized that the variation in outcomes at the hospital level after reoperation would be significant. After accounting for this variability, some patient-level clinical criteria could be identified to help inform treatment decisions in this patient populat
Background and purpose — Concerns exist regarding the generalizability of results from randomized controlled trials (RCTs) evaluating arthroscopic partial meniscectomy (APM) to treat degenerative meniscus tears. It has been suggested that study populations are not representative of subjects selected for surgery in daily clinical practice. There-fore, we aimed to compare patients included in trials
How colour polymorphisms are maintained in natural populations constitutes a key subject of study for evolutionary ecologists. One of the mechanisms that has been put forward to explain this phenomenon is negative frequency-dependent selection, which can be caused by different mechanisms. Among these mechanisms is mate choice, or the selection as a potential mate of the rare or dissimilar colour m
Abstract in French:Cette recherche s'intéresse à la mobilisation transnationale de la diaspora autour du vote externe et à l'implication des organisations diasporiques dans le processus électoral du pays d'origine. Plusieurs approches expliquent la transnationalisation politique des groupes diasporiques ; cependant, elles ne parviennent pas à clarifier (1) comment certains moments historiques (parThis research is concerned with transnational diaspora mobilisation around external voting and diaspora organisations’ involvement in the homeland electoral process. There are several approaches that explain the political transnationalisation of the diasporic groups; yet, they fail to clarify (1) how some historical moments (e.g., extending the voting right to non-resident nationals) can generate
BACKGROUND: Little is known about whether the recommended, non-pharmacological treatments for chronic pain yield reductions in healthcare utilization, social costs and increased productivity in actual practice.METHODS: The primary aim of this study ( n = 232) was to conduct secondary analyses of health economic outcomes using data from national registries combined with clinical outcome data from
External quality assessment (EQA) schemes for pathology are essential, yet large/international programmes do not assess morphology-based biomarkers or address local/regional needs. This study outlines bottom-up initiated, flexible Swedish Digital Pathology EQA rounds for breast pathology, and presents results from the 2021 and 2023 rounds. Six breast carcinoma cases were selected for each EQA roun
Background: The growing challenges of population aging create a pressing need for specialized geriatric medicine services to effectively address the complex health needs of older adults and influence supportive healthcare policies. Older patients may present clinical complexity with multimorbidity, disability, and/or frailty, necessitating a shift from the traditional organ-oriented clinical appro
With 23,000 registered participants and unprecedented media attention, the 16th conference of the parties (COP) to the United Nations Convention on Biological Diversity (CBD) in Cali, Colombia, was the largest in the 32-year history of these biannual meetings. In terms of successes, the Cali conference established a new subsidiary body to protect concerns of indigenous communities and local popula
This article summarizes the current understanding of the heterogeneity of type 1 diabetes from a June 2024 international Expert Forum organized by the editors of Diabetes, Diabetes Care, and Diabetologia. The Forum reviewed key factors contributing to the development and progression of type 1 diabetes and outlined specific, high-priority research questions. Knowledge gaps were identified, and, not
This article summarizes the current understanding of the heterogeneity of type 1 diabetes from a June 2024 international Expert Forum organized by the editors of Diabetes, Diabetes Care, and Diabetologia. The Forum reviewed key factors contributing to the development and progression of type 1 diabetes and outlined specific, high-priority research questions. Knowledge gaps were identified, and, not
Background: Studies on national policies for biologics are warranted. Objectives: To map and compare national healthcare set-ups for prescription, start, switch, tapering, and discontinuation of biologic/targeted synthetic disease-modifying antirheumatic drugs (DMARDs) in patients with psoriatic arthritis and axial spondyloarthritis across Europe, and assess the healthcare set-ups in relation to c
We present the artillery of a well-preserved late medieval Danish-Norwegian carvel warship, Gribshunden. Probably built in the Netherlands in 1484, the ship served King Hans until sinking in June 1495. Of its original 50 or more guns, elements of 11 have been recovered and digitally recreated, and more remain on the wreck. Investigation of this site provides insights into the development of shipboWe present the artillery of a well-preserved late medieval Danish-Norwegian carvel warship, Gribshunden. Probably built in the Netherlands in 1484, the ship served King Hans until sinking in June 1495. Of its original 50 or more guns, elements of 11 have been recovered and digitally recreated, and more remain on the wreck. Investigation of this site provides insights into the development of shipbo
Most agricultural and food policies often overlook diversity of farming households, resulting in generalized and ineffective interventions. Recognizing changing and diverse characteristics of farm types is therefore critical. Using data from 502 households in West Pokot County, Kenya, we employ principal component and cluster analyses to create farm typologies to guide targeted policy intervention
