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Objectives: To explore reasons for institutionalization of people with dementia according to informal caregivers as well as variation in reasons between countries. Design: An explorative cross-sectional study was conducted in 8 European countries. Setting: Per country, a minimum of 3 long term care facilities, offering care and accommodation as a package, participated in this study. Participating

Health information system (HIS) refers to a data collection and management system that supports the use of health information for planning, management and decision making. Robust HISs are required for the proper management of health data to produce and share high-quality health information for informing planning and decision making at different levels of the health system. This chapter presents th

This study investigates the role of multi-stakeholder networks in disaster risk management (DRM) capacity development and how it aligns with the principles of the Sendai Framework for Disaster Risk Reduction. While the Framework emphasises collaboration, coordination, and partnerships among diverse stakeholders, there remains a gap in understanding how networks foster and sustain collaborative DRM

Antibody microarrays are becoming increasingly established in clinical studies. However, the arrays are seldom used in a quantitative approach but rather for detecting up or down regulated proteins. In this study we describe a microarray procedure being standardized by placing the in-house developed porous silicon surfaces into a commercially available 96 well microtiter plate for analyzing the PS

An Integrated Selective Enrichment Target (ISET), microfabricated for efficient on-bead enzymatic digestion of proteins compatible for a direct interface with matrix-assisted laser desorption /ionization mass spectrometry (MALDI MS) is presented.

IntroductionUse of long-term oxygen therapy (LTOT) for more than 15 h per day does not reduce mortality or hospitalizations, but may increase the risk of adverse events. We evaluated the relationship between daily oxygen use duration and adverse events, symptoms, and health status in patients on LTOT.MethodsThis was a cross-sectional survey study of a random sample (N = 650) of adults with ongoing

The paper provides an overview and preliminary results from ongoing research with the aim to evolve cross-laminated timber (CLT) into the next generation of Tailored Laminated Timber (TLT). This is done by exploring innovative concepts that optimize the mechanical performance, while simultaneously ensuring adherence to circular economy principles. The current study aims at investigating the potent

This chapter introduces systematic reviews and provides a summary of systematic review methods. Because of the challenges in palliative care trials, systematic reviews might be even more relevant in palliative care than in many other areas of health care. This chapter highlights the reasons why a researcher should use a systematic review, as well as the instances when systematic reviews are not an

INTRODUCTION: While the characteristics and medical management of patients treated with long-term oxygen therapy (LTOT) have transformed during the last decades, the evidence base for LTOT itself remains largely unchanged. This study aimed to compare the risk of hospitalization and death among hypoxemic patients discontinuing LTOT, with that of controls continuing therapy.METHODS: This was a retro

ObjectivesUncertainty among healthcare providers about patients’ ability to make care decisions is a barrier to shared decision-making. We aimed to assess the self-reported decision-making ability of patients with cancer at the end of life.MethodsData from 11 countries of adults with a limited life expectancy and cancer as the primary diagnosis were used. Participants completed a questionnaire, in

Aims: The main aim of the present study was to identify factors influencing health-related quality of life (HRQoL), as measured by EQ-5D-5L, in individuals 1 year after the acute phase of COVID-19.Methods: This cross-sectional study included 75 participants (51% females), 1 year after confirmed SARS-CoV-2 infection (76% hospitalised). Associations between HRQoL, measured by patient-reported outcom

PURPOSE: To examine sex differences in health-related quality of life (HRQoL) among patients surgically treated for renal cell carcinoma (RCC) in Sweden, utilizing data from the National Swedish Kidney Cancer Register (NSKCR).METHODS: In this study of 4658 surgically treated RCC patients, data on HRQoL, clinical, demographic, and socioeconomic characteristics were retrieved from the NSKCR for pati

BackgroundEarly Absenteeism Guide for Lifelong Education (EAGLE) is an early, school-based intervention designed to help school personnel address emerging school absenteeism. EAGLE aims to support early identification, strengthen school–parent collaboration, and guide parents in managing school attendance through a holistic assessment framework.ObjectiveThis qualitative exploratory study investiga

Background Sirolimus-coated balloons (SCB) are a potential alternative to paclitaxel-coated balloons (PCB) in the context of percutaneous coronary intervention (PCI). However, comparative data between SCB and PCB remain limited. We aimed to compare the outcome of PCI with contemporary PCB or SCB in a real-world clinical setting. Methods The Swedish Coronary Angiography and Angioplasty Registry (SC

Popular Abstract in Swedish Benskörhet (osteoporos) är en sjukdom som karaktäriseras av låg benmassa och försämrad benkvalitet, en sjukdom som leder till ökad risk för frakturer. Benskörhetsfrakturer uppkommer vanligen i handleder, axelleder, kotor, bäckenben, höftleder och knäleder. Frakturerna drabbar kvinnor oftare än män, något som till stor del beror på att nivåerna av det kvinnliga könshormoThe aim of this thesis was to identify the influence of calcium, physical activity and detraining on bone mass and bone size in girls and young women. We hypothesised that calcium intake above a specific level does not enhance the accrual of bone mineral, that exercise predominantly influences the skeleton in the early pubertal period and that reduced training is followed by a loss of exercise-ind

We have recently reported that the inner layers of the arteries, the intima-media complex, of common carotid artery, move as much in the longitudinal direction as in the radial direction, during the cardiac cycle. In order to study this phenomenon we have developed a high-resolution ultrasonic method that can simultaneously record both the longitudinal and the radial movements of the arterial wall

Popular Abstract in Swedish Kväveoxid (NO) och framför allt kolmonoxid (CO) tillhör de giftigaste gaserna man känner till. Vem har inte läst i kriminalromaner om hur människor stängts in i garage och gasats ihjäl med kolmonoxid från arbetande bilmotorers avgasutsläpp. Under det senaste årtiondet har man kunnat visa att dessa gaser i själva verket bildas i vår egen kropp och att de utgör signalmoleDuring the last decade it has been shown that nitric oxide (NO) and carbon monoxide (CO) are produced in our own body, and that they constitute a novel class of messenger molecules. In 1992 a constitutive NO-producing NO-synthase (cNOS) was found in the islets of Langerhans, and in 1997 we could show for the first time that the islets also contained a CO-producing constitutive heme oxygenase (HO-2

Observations based on overexpression of the suppressor gene p53 or interference with endogenous p53 support a role for p53 in mediating not only growth inhibition and apoptosis but also differentiation. The aim of this study was to characterize the mechanisms of p53-dependent differentiation in the monoblastic leukemia cell line U-937. These cells were transfected with a mutant of the p53 gene exp

Popular Abstract in Swedish Hur man värderar resultat av kirurgisk behandling av ländryggens degenerativa åkommor är ett stort, komplext och delvis kontroversiellt ämne. Denna avhandling studerar resultatvärdering med olika metoder och instrument, huvudsakligen baserat på resultat från det nationella svenska ländryggskirurgiregistret. Arbete I. Inventering av befintliga instrument i litteraturen No consensus regarding outcomes assessment in spine patients exists. Health-Related Quality of Life (HRQoL) questionnaires are increasingly used. The objective of this thesis was the evaluation of HRQoL measures before and after lumbar spine surgery, and their relation to other evaluation parameters as well as relevance of differences. The patients included were operated on for lumbar spine disor