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Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease

Objective:To compare the diagnostic accuracy of CSF biomarkers and amyloid PET for diagnosing early-stage Alzheimer disease (AD).Methods:From the prospective, longitudinal BioFINDER study, we included 122 healthy elderly and 34 patients with mild cognitive impairment who developed AD dementia within 3 years (MCI-AD). -Amyloid (A) deposition in 9 brain regions was examined with [F-18]-flutemetamol

Heart rate modeling and prediction using autoregressive models and deep learning

Physiological time series are affected by many factors, making them highly nonlinear and nonstationary. As a consequence, heart rate time series are often considered difficult to predict and handle. However, heart rate behavior can indicate underlying cardiovascular and respiratory diseases as well as mood disorders. Given the importance of accurate modeling and reliable predictions of heart rate

Styrelses möjlighet att besluta om kapitalavyttringar till sponsring

I takt med att det har blivit dyrare för bolag att marknadsföra sig själva genom de traditionella marknadsföringsmetoderna har bolag börjat leta efter nya och kostnadseffektiva marknadsföringsalternativ. Sponsring har därför under de senaste åren blivit allt mer populärt. Detta märks inte minst genom att sponsring blivit allt vanligare under idrottsevenemang där bolag använder idrotternas goodwillIn recent year it has been more expensive than ever for companies to promote themselves via different marketing strategies. The companies have been looking for new and cost-effective alternatives instead of the classic marketing strategies. Sponsorship is one such strategy that has proven very popular, especially sponsorship during sporting events, where companies use the goodwill of sports to str

The Rights of Children in EU Law - A case law study regarding children's rights within the paradigms of instrumentalism, individualism and protectionism

Inom rättsområdet fri rörlighet av arbetare har barnet givits en rätt under Artikel 12 till utbildning i Förordning 1612/68 som barnet kan göra burk av i värd Medlems Staten. För att barnets rätt till utbildning ska bli tillämplig måste barnet flytta och bo tillsammans med föräldern som är arbetare. Likabehandlingsprincipen är tillämplig tillsammans med rätten till utbildning vilken kräver att MedWithin the legal field free movement of workers the child has been given a right under Article 12 in Regulation 1612/68 to education in the host Member State. For the right to apply the child has to move and reside with the worker. The principle of equal treatment applies to the provision, which requires that, the Member State does not discriminate against children to workers. To give the right fu

Atelier Transylvania - An ethical fashion production through architecture

The author of this work has launched a Swedish brand producing fine quality leather goods and acquired an atelier operating in the heart of Transylvania, Romania, with the manufacturing of leather goods since 1991. The production house now needs a new building in Cluj in order to grow and meet the new work ethics. As a response to the collapse of a sewing factory building in Bangladesh 2013, kill

Methods to Automatically Transform MR Images of the Brain into the AC-PC Coordinate System

One way to reduce the growing workload for radiologists is to automate the trans- formation of 3D MR images of the brain into the AC-PC coordinate system. In this thesis, both non-deformable and deformable image registration methods were used to register images to a template in the desired space, the AC-PC coordinate system. First, three non-deformable transformations were used together with three

Faderskapspresumtionen - En föråldrad huvudregel

Arbetet utreder faderskapspresumtionen och närliggande rättsområden. Syftet med detta är att granska presumtionen och utvärdera om denna är att anse fyll-ler sitt syfte. Detta görs genom att analysera såväl hur det sett ut historiskt som att konstatera hur den gällande rätten ser ut. Detta har även ställts emot de intressen som finns i samhället, hos föräldrarna samt principen om barnets bästa. HThe project audits the presumption of fatherhood in the Swedish legal system and related legal areas. This is done to evaluate if the presumption is fulfilling its purpose. To achieve this a thorough analysis of the subject is conducted. The history of the legal area is explored, and the applicable law is reviewed. The interests in of the different involved parties such as the parents and the publ

Samarbetssamtal och inomrättslig medling i mål om vårdnad, boende och umgänge

Den svenska familjerättsliga regleringen har sedan länge präglats av strävan att söka tillgodose barnets intresse i relation till föräldrarna. Ett tydligt uttryck för denna strävan finner man i föräldrabalkens 6 kap. 2 a § där det stadgas att barnets bästa ska vara avgörande för alla beslut om vårdnad, boende och umgänge. En ytterligare strävan i den familjerättsliga regleringen har varit att söka

Corvellec aff sem hbg 26sep 2018 short

Handledningsaritmetik Avfallsförebyggande handlar inte om avfall Hervé Corvellec Institutionen för tjänstevetenskap Lunds universitet 1. Aktivister leder arbetet för avfallsförebyggande Presentatör Presentationsanteckningar Aktivister leder arbetet för avfallsförebyggande: Många innovativa aktiviteter för avfallsförebyggande uppstår på gräsrotsnivå, i med­borgardrivna ideella projekt. Därefter plo

https://www.ses.lu.se/sites/ses.lu.se/files/corvellec_aff_sem_hbg_26sep_2018_short.pdf - 2026-05-03

A Comprehensive Evaluation of Consensus Spectrum Generation Methods in Proteomics

Spectrum clustering is a powerful strategy to minimize redundant mass spectra by grouping them based on similarity, with the aim of forming groups of mass spectra from the same repeatedly measured analytes. Each such group of near-identical spectra can be represented by its so-called consensus spectrum for downstream processing. Although several algorithms for spectrum clustering have been adequat

AIRR Data Under the E.U. Trade Secrets Directive: Aligning Scientific Practices with Commercial Realities

Whether the E.U. Trade Secrets Directive sufficiently and appropriately covers cutting-edge complex technologies is of critical interest to policy-makers, scientists, and commercial developers alike. One such technology—adaptive immune receptor repertoire sequencing, or AIRR-seq—raises difficult questions concerning what information is and should be protected under the new Directive, and how to be

Towards the ranking of airborne particle emissions from car brakes - A system approach

Airborne particulate matter emitted from motor vehicle brakes is a contributor to urban air quality. Therefore, a method to rank brake pairs (pads and rotors) with respect to their particle emission factors in a reliable way is needed to develop a low-emission disc brake. A novel inertial disc brake dynamometer designed for brake particle emission studies, a modified SAE J 2707 cycle, an electrica

MXCuBE3 : A New Era of MX-Beamline Control Begins

The outstanding success of structural biology within the last two decades is closely related to the development and evolution of macromolecular crystallography (MX) beamlines. Indeed, many of today's synchrotron-based MX experimental sessions aim for fast but rigorous evaluations and data collections from very large numbers of samples [1–7]. To facilitate this, sample changing on most MX beamlines

Mixed-species associations can arise without heterospecific attraction

Despite widespread research on the interaction rules that drive group-living behavior in animals, little is known about the spatial self-organization of individuals in heterospecific groups. This has led to significant challenges in teasing apart the various mechanisms thought to underpin multispecies groups. One potentially useful approach for gaining an understanding of this process is to identi

Review of acoustic comfort evaluation in dwellings : Part III—airborne sound data associated with subjective responses in laboratory tests

Acoustic comfort has been used in engineering to refer to conditions of low noise levels or annoyance, while current standardized methods for airborne and impact sound reduction are used to assess acoustic comfort in dwellings. However, the results and descriptors acquired from acoustic measurements do not represent the human perception of sound or comfort levels. This article is a review of labor

Ship-Generated Waves and Induced Turbidity in the Gota alv River in Sweden

Ship-generated waves were investigated in the Gota alv river, which is a major waterway on the Swedish west coast between the sea and Lake Vanern. Ships with a typical size of 85x15x5 m (lengthxwidthxdraft) travel at speeds between 5 and 10 knots, generating waves that cause sediment transport and erosion along the river bed and banks. Field measurements of the wave properties and turbidity were c