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Background: The first interim analysis of the phase III, randomized, double-blind, placebo-controlled, multinational TITAN study demonstrated improved overall survival (OS) and radiographic progression-free survival (rPFS) with apalutamide added to ongoing androgen deprivation therapy (ADT) in patients with metastatic castration-sensitive prostate cancer. The final analysis confirmed improvement i

BACKGROUND: Healthcare today is a complex system with increasing needs of specific knowledge of evaluation of research and implementation into clinical practice. A critical issue is that we all apply evidence-based practice (EBP) with standardised methods and continuing and systematic improvements. EBP includes both scientific and critical assessed experience-based knowledge. For the individual,

Background & objectives: Endoscopy is the current gold standard for evaluation of disease activity in ulcerative colitis. The Mayo Endoscopic Subscore (MES) is commonly used for quantifying disease activity, but it has several weaknesses. Numerous new endoscopic indices have been developed but none of these have been widely implemented, likely due to limited feasibility. The primary objective

Background: The molecular pathways linking short and long sleep duration with incident diabetes mellitus (iDM) and incident coronary heart disease (iCHD) are not known. We aimed to identify circulating protein patterns associated with sleep duration and test their impact on incident cardiometabolic disease. Methods: We assessed sleep duration and measured 78 plasma proteins among 3336 participants

Background and Purpose: The aim of the Synergium was to devise and prioritize new ways of accelerating progress in reducing the risks, effects, and consequences of stroke. Methods: Preliminary work was performed by 7 working groups of stroke leaders followed by a synergium (a forum for working synergistically together) with approximately 100 additional participants. The resulting draft document ha

Purpose: The purpose of this study is to investigate the role of working from home within family friendly work policies (FFWPs) and its relationship to firm performance, and whether this is affected by the choice of management practices within an organization. Methodology: A cross-sectional dataset from 2004, including data from 732 firms and four countries, accessed through World Management Sur

The aviation industry is perceived as being unsustainable in the long term due to foreseen continuous growth and the use of finite natural resources. To become more sustainable airlines need to address sustainability in their business model and business strategies. This research explores how the two airline carrier types, Ryanair, an LCC, and Scandinavian Airlines (SAS), an FSC, have addressed sus

The emerging market for meat substitutes has largely been filled with different types of soy products. Although soy usually has a lower environmental impact than meat, soy is not entirely unproblematic. Deforestation and global transportations are two negative effects of the increasing production of soybeans. One of these meat substitutes is tempeh: an Indonesian mold-fermented food usually made o

Surrogatarrangemang har varit kraftigt debatterat i Sverige. I dagens läge finns ingen reglering på området. Surrogatarrangemang sker dock ändå genom att svenskar åker utomlands eller utför heminsemination. Detta innebär att barn tillkommer men det finns ingen reglering som hanterar dess rättsliga förhållanden. Syftet med uppsatsen är att undersöka om en framtida reglering av altruistiskt surrogaSurrogacy arrangements have been heavily debated. Today, there is no legislation regarding surrogacy arrangements in Sweden. However, the phenomena still take place by Swedes going abroad or performing private insemination. This leaves the legal situation for families with surrogate-born children uncertain. The purpose of the thesis is to examine whether a future regulation of altruistic surrogat

Den här uppsatsen är inspirerad av en omtalad dom från Svea Hovrätt som meddelades i februari 2019. Svea Hovrätt beslutade att tilldela en pappa ensam vårdnad om sina barn, trots att han ett par år tidigare dömdes till fängelse för att ha misshandlat dem. Anledningen till vårdnadsöverflyttningen var att mamman gjort sig skyldig till umgängessabotage. Uppsatsen syftar till att utreda umgängessabotaThis paper is inspired by the well-known and disputed judgment from Svea Court of Appeal passed in February of 2019. Svea Court of Appeal decided to assign a father sole custody of his children, despite of having been sentenced to prison a couple of years earlier for assaulting them. The reason behind the change in custody was the mother sabotaging the children’s right to visitation with their fat

In this thesis, I have studied male and female selective mechanisms that can affect plant reproductive success and gene flow. I have focussed on sexually selected traits, mainly pollen competition and maternal sorting mechanisms, for example through non-random ovule abortion. The main question was; what kind of traits can influence the most successful pollen donor or maternal sorting process? I fo

The aim of this study is to examine whether there exists a right of humanitarian intervention in customary international law. The point of departure is the principle of non-use of force in customary international law. The International Court of Justice established in the Nicaragua Case that the principle of non-use of force not only is a jus cogens norm, but that it also has the basic identity of

Background and Purpose-The aim of the Synergium was to devise and prioritize new ways of accelerating progress in reducing the risks, effects, and consequences of stroke. Methods-Preliminary work was performed by 7 working groups of stroke leaders followed by a synergium (a forum for working synergistically together) with approximately 100 additional participants. The resulting draft document had

Background and Purpose The aim of the Synergium was to devise and prioritize new ways of accelerating progress in reducing the risks, effects, and consequences of stroke. Methods Preliminary work was performed by seven working groups of stroke leaders followed by a synergium (a forum for working synergistically together) with approximately 100 additional participants. The resulting draft document

The Storo greenstone belt in Godthabsfjord, southern West Greenland consists of juxtaposed rock units of different age and origin, and hosts gold mineralisation that is associated with arsenopyrite along a contact between lithological units and along the axial plane of a large fold core. The age and origin of the gold is debatable, but in this paper, we present new arsenopyrite Re-Os and zircon U-

We studied clinical performance of serum TRACP 5b and other bone turnover markers, including S-CTX, U-DPD, S-PINP, S-BALP, and S-OC, for monitoring alendronate treatment. TRACP 5b had higher clinical sensitivity, area under the ROC curve, and signal-to-noise ratio than the other markers. INTRODUCTION: The purpose of this study was to compare the clinical performance of serum TRACP 5b (S-TRACP5b) w

Popular Abstract in Swedish Faderskap är en familjepolitisk angelägenhet där staten går in och intervenerar och på så sätt fostrar fäder. Tyngdpunkten ligger på att uppmuntra fadersnärvaro och att förmå frånvarande fäder att ta ansvar för sina barn. Detta ger oss en bild av vad som uppfattas som bra fäder och vad som avviker från normen. Den sociala barnavården är en kontext som verkar inom den soThis dissertation deals with fathers of children subjected to child welfare investigations. They are "fathers called into question" and their fatherhood is not very much investigated so far. The dominating picture is that the fathers are absent, to their children as well as in research and social work literature. Two Swedish contexts are presented. These represent different interpretations of "the

Vi Varga, MSc in Bioinformatics, 2022PhD student at Gothenburg University Sweden.I now work as a PhD student at the Chalmers University of Technology in Gothenburg, Sweden. Specifically, I am at the Division of Systems and Synthetic Biology, within the Department of Life Sciences.  Here I work on two primary projects: orthologous clustering and functional annotation of the genome of the bacterial

https://www.biologyeducation.lu.se/education/career/meet-our-bioinformatics-alumni - 2026-05-07