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Navigating in the landscape of ambiguity: A stakeholder approach to the governance and management of hybrid organisations

Popular Abstract in Swedish Utvecklingen av offentlig sektor har de senaste årtiondena till stor del påverkats av New Public Management. Som en konsekvens av detta har en ”marknadisering” av offentliga verksamheter och organisationer skett. Denna ”marknadisering” har resulterat i att det finns organisationer i offentlig sektor som varken passar in på beskrivningen av offentliga organisationer elleDuring the last decades the influence of New Public Management and the “marketisation” of public services, have given us organisations in the public sector that fit neither the mould of what constitutes public sector organisations nor that of private companies. Instead, we now have so-called hybrid organisations. These have become an attractive alternative to the more “bureaucratic” public agencie

Hierarchical Structure of Wireless Systems - an Analytical Performance Study

Sammanfattning-The use of hierarchical structures for providing excellent wireless connections for customers has attained growing attention. Models to investigate the QoS requirements rather quickly become complicated and hard to analyze. In the paper a first rough analytical approach for the answer is given. As the users devote more and more time to be connected through wireless connections, and

Conditional Partial Plans for Rational Situated Agents Capable of Deductive Reasoning and Inductive Learning

Rational, autonomous agents that are able to achieve their goals in dynamic, partially observable environments are the ultimate dream of Artificial Intelligence research since its beginning. The goal of this PhD thesis is to propose, develop and evaluate a framework well suited for creating intelligent agents that would be able to learn from experience, thus becoming more efficient at solving thei

Trade-off analysis for requirements selection

Evaluation, prioritization and selection of candidate requirements are of tremendous importance and impact for subsequent software development. Effort, time as well as quality constraints have to be taken into account. Typically, different stakeholders have conflicting priorities and the requirements of all these stakeholders have to be balanced in an appropriate way to ensure maximum value of the

Variability in muscle fibre areas in whole human quadriceps muscle: how to reduce sampling errors in biopsy techniques

A single biopsy is a poor estimator of the muscle fibre cross-sectional area (CSA) for a whole human muscle because of the large variability in the fibre area within a muscle. To determine how the sampling errors in biopsy techniques can be reduced, data on the CSA of type 1 and type 2 fibres obtained from cross-sections of whole vastus lateralis muscle of young men, have been analysed statistical

Dermatan sulfate domains defined by the novel antibody GD3A12, in normal tissues and ovarian adenocarcinomas

Dermatan sulfate (DS) expression in normal tissue and ovarian cancer was investigated using the novel, phage display-derived antibody GD3A12 that was selected against embryonic glycosaminoglycans (GAGs). Antibody GD3A12 was especially reactive with DS rich in IdoA-GalNAc4S disaccharide units. IdoA residues are important for antibody recognition as DS polymers with low numbers of IdoA residues were

Isolation of Anacardic Acid from Natural Cashew Nut Shell Liquid (CNSL) Using Supercritical Carbon Dioxide.

Solvent extracted cashew nut shell liquid (CNSL), conventionally known as natural CNSL, is a mixture of several alkenyl phenols. One of these alkenyl phenols is anacardic acid, which is present at the highest concentration. In view of anticipated industrial applications of anacardic acid, the objective of this work was to isolate anacardic acid from natural CNSL by supercritical carbon dioxide (sc

Biomonitoring of lead exposure-alternatives to blood

Lead (Pb) is one of the most important models for biomonitoring of exposure, with the blood Pb concentration as a predominant choice in practice and in epidemiology. In this article the alternatives for biomarkers to blood are reviewed. This overview focuses on a number of different qualities that are of importance in the evaluation of a biomarker's usefulness and performance. The qualities scruti

Environmental influences on exopolysaccharide formation in Lactobacillus reuteri ATCC 55730.

Lactobacillus reuteri is known to produce exopolysaccharides (EPS), which have the potential to be used as an alternative biothickener in the food industry. In this study, the effect of several environmental conditions on the growth and EPS production in the L. reuteri strain ATCC 55730 was determined. The expression of the corresponding reuteransucrase gene, gtfO, was investigated over time and t

The prognostic significance in Goodpasture's disease of specificity, titre and affinity of anti-glomerular-basement-membrane antibodies.

Background: The nephrotoxic potential of anti-glomerular-basement-membrane (GBM) antibodies has been demonstrated in numerous animal experiments. However, it is not known to what extent the properties of circulating anti-GBM antibodies in human disease reflect the severity of the disease and predict the outcome. Methods: Clinical data were collected for 79 Swedish patients for whom a positive resu

Compliance with treatment and understanding of own disease in patients with severe and moderate haemophilia

It is well known that teenagers with chronic diseases have problems complying with their treatment. The aim of this study was to evaluate the patient's knowledge of haemophilia and his compliance to prophylactic treatment, and the age at which the patient took over the responsibility for his disease and to create educational material for teenagers and adolescents. This was a prospective multicentr

A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer

Randomized clinical trials have established the role of third-generation aromatase inhibitors (AIs) (letrozole, anastrozole, and exemestane) as standard treatment for patients with hormone-sensitive metastatic breast cancer who have experienced disease progression with antiestrogen therapy. Significant gains in clinical efficacy and improved tolerability over progestins (megestrol acetate) and the

Apomorphine in the treatment of Parkinson's disease

Apomorphine is a potent, nonselective, direct-acting dopamine-receptor agonist. Given subcutaneously, it has a rapid onset of antiparkinsonian action qualitatively comparable to that of levodopa. Despite its long history, it was not until peripheral dopaminergic side effects could be controlled by oral domperidone that the clinical usefulness of apomorphine in Parkinson's disease began to be inves

Environment, social interaction, and physical activity as determinants of functional outcome after cerebral infarction in the rat

Rats housed in an enriched environment allowing both social interaction and physical activity improve more than rats housed in standard laboratory cages after focal brain ischemia. To determine the relative importance of social and physical activity, rats that sustained ligation of the middle cerebral artery were kept in an enriched environment with opportunities for various activities (group A),

A customizable pattern-based software process simulation model: design, calibration and application

Software process analysis and improvement relies heavily on empirical research. Empirical research requires measurement, experimentation, and modeling. However, whatever evidence is gained via empirical research is strongly context dependent. Thus, it is hard to combine results and capitalize upon them for the purpose of improvement in evolving development environments. The process simulationmodel

Genetic Diversity and Population Structure in a Legacy Collection of Spring Barley Landraces Adapted to a Wide Range of Climates

Global environmental change and increasing human population emphasize the urgent need for higher yielding and better adapted crop plants. One strategy to achieve this aim is to exploit the wealth of so called landraces of crop species, representing diverse traditional domesticated populations of locally adapted genotypes. In this study, we investigated a comprehensive set of 1485 spring barley lan

Ethical issues in physiotherapy - Reflected from the perspective of physiotherapists in private practice.

Background: An important aspect of physiotherapy professional autonomy is the ethical code of the profession, both collectively and for the individual member of the profession. The aim of this study is to explore and add additional insight into the nature and scope of ethical issues as they are understood and experienced by Danish physiotherapists in outpatient, private practice. Methods: A qu