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The protein Painless is an ion channel coupled receptor that is present in the mosquito Aedes aegypti transmitting yellow fever. The protein is activated by noxious heat. It has been a long-term goal to determine the protein structure and consequently be able to develop a mosquito repellant. The aims of the thesis were to purify and isolate heterologously expressed Painless from yeast cells and ex

High-latitude ecosystems are undergoing rapid climate warming, yet long-term ecological response remain poorly understood due to the scarcity of sustained monitoring records. We analyse a unique 40-year dataset from a subarctic mountain birch ( Betula pubescens ssp. czerepanovii ) ecosystem in northern Fennoscandia, integrating climate, plant reproduction, insect herbivory, phenology, and large he

The main aim of this study was to apply and compare two GIS-based data mining models, namely support vector machine (SVM) by four kernel functions (linear-SVM, polynomial-SVM, radial basic function-SVM, and sigmoidal-SVM) and entropy models in landslide susceptibility mapping, in Shangzhou District, China. Initially, 145 landslide locations were mapped using early reports, aerial photographs, and

It is becoming increasingly clear that we need an integrated approach to understanding and encouraging transitions towards a sustainable energy system. Current overall unsustainable ‘practices’ are locked into cultural, material, institutional and infrastructural settings. This limits the scope for individual choice and action. Even when actions are taken on individual or project level, they often

BACKGROUND: Bronchodilator responsiveness (BDR) in asthma involves both the central and peripheral airways but is primarily relieved with beta-2-agonists and evaluated by spirometry. To date, antimuscarinics can be added as a reliever medication in more severe asthma. We hypothesize that combining both short-acting beta-2 agonist (SABA) and short-acting muscarinic antagonist (SAMA) could also impr

Trap roads are a part of the Swedish railway facility and resembles the safest front- and side protection at speed above 160 km/h. When designing Trap roads, some regulations needs to be followed. As these, in some cases, may be contradictory towards each other, the planners become somewhat insecure. The purpose of the master thesis has thenceforth been to clarify for the planners, as well as to w

Detta arbete berör ämnet återbruk och återanpassning av en befintlig byggnad i en nutida kontext. Byggnaden som jag valt att studera är Sundhammars barnkoloni, byggd år 1937, belägen invid kusten i södra Bohuslän. Trots att byggnaden bedöms vara en av de bäst bevarade barnkolonibyggnaderna så saknar den skydd, varpå den vid flertalet tillfällen hotats av rivning. Målet med detta examensarbete ä

This Master’s Thesis was written in collaboration with Handelsbanken Asset Man- agement in Stockholm, through the Faculty of Engineering at Lund University. This paper aims to investigate algoritmic trading on the financial market from a theo- retical and a practical perspective. The theoretical section presents an approach of using sentiment analysis for predicting asset price movements. The algo

Ett barn kan placeras i familjehem genom bestämmelser i SoL respektive bestämmelser i LVU. När placeringen varat i tre år från det att beslutet verkställdes har socialnämnden enligt 6:8 2 st. SoL respektive 13 § 3 st. LVU en särskild skyldighet att överväga om det finns skäl att ansöka om överflyttning av vårdnad i enlighet med 6:8 FB. I mars 2022 lämnade regeringen en proposition vid namn BarnetsA child can be placed in a family home through regulations in the Social Services Act and the Care of Young Persons (Special Provisions) Act. When the placement has lasted a total of three years, from the time of implementation, the social welfare committee has an obligation to consider whether there are grounds to apply for transfer of custody in accordance with Chapter six, section eight in the

The growth of the wild boar (Sus Scrofa) population in Sweden results in increasing wild boar damage on agricultural grounds, thereby influencing the livelihoods of farmers. Finding mitigation strategies that are positive for both wildlife and human society is challenging. It is therefore essential to enable the creation and investigation of precise and differentiated wild boar management strategi

Due to the increasing CO2 concentrations in the atmosphere caused by anthropogenic greenhouse gas emissions, there is a need for adaptations and mitigations to climate change. Not only is a drastic reduction of emissions necessary, but the uptake of CO2 from the atmosphere needs to be increased and stored long-term. One of the more efficient mitigation strategies to reduce CO2 concentrations in th

Projekt Turnstone är ett samverkansprojekt delvis finansierat av Europeiska kommissionen. Projektet är ett initiativ av Stockholmspolisens gränsbevakningsenhet. Samverkanspartners i projektet är Svenska Kustbevakningen, Region Nord öst; Helsingforspolisen; Gränsbevakningsväsendet, Finland; Polis och Gränsbevakningen i Estland; Statliga Gränsbevakningen, Lettiska republiken; och den Statliga GränssProject Turnstone is a collaborative project funded in part by the European Commission. The project is an initiative by the Stockholm Police. Collaborating partners in the project are the Swedish Coast Guard, Region Northeast; the Helsinki Police; the Gulf of Finland Coast Guard District; the Police and Border Guard Board in Estonia; the State Border Guard of the Republic of Latvia; and the State

Background: Rheumatic diseases commonly affect joints and other structures in the hand. Surgery is a traditional way to treat hand problems in inflammatory rheumatic diseases with the purposes of pain relief, restore function and prevent progression. There are numerous measures to choose from, and a combination of outcome measures is recommended. This study evaluated if instruments commonly used i

Background: Integument-related toxicities are common during epidermal growth factor receptor (EGFR)-targeted therapy. Panitumumab is a fully human monoclonal antibody targeting the EGFR that significantly improves progression-free survival when added to chemotherapy in patients with metastatic colorectal cancer who have wild-type (WT) KRAS tumours. Primary efficacy and tolerability results from a

Popular Abstract in Swedish I denna avhandling undersöker vi vilka anpassningar som behöver göras i designen av matematikkurser när de överförs från en kulturell miljö till en annan. Vi fokuserar på en kurs i beräkningsmatematik som undervisas på Lunds Universitet i Sverige och som vi under studien överförde till Sorans Universitet i Kurdistan/Irak. Projektet har två delar. Den första diskuterar hThis thesis aims to investigate necessary adaptations in the design of a mathematics course when it is transferred from one cultural environment to another. We focus on an elementary course in computational mathematics with Python taught at Lund University, Sweden, and at Soran University, Kurdistan/Iraq. This project holds two main parts. The first part elucidates how the necessary changes in tea

Background: In this prospective study, mentally disordered perpetrators of severe violent and/or sexual crimes were followed through official registers for 59 (range 8 to 73) months. The relapse rate in criminality was assessed, compared between offenders sentenced to prison versus forensic psychiatric care, and the predictive ability of various risk factors (criminological, clinical, and of struc

NILE ("New Improvements for Lignocellulosic Ethanol") was an integrated European project (2005-2010) devoted to the conversion of lignocellulosic raw materials to ethanol. The main objectives were to design novel enzymes suitable for the hydrolysis of cellulose to glucose and new yeast strains able to efficiently converting all the sugars present in lignocellulose into ethanol. The project also in

Hur många gånger har du tagit på dig en svart tröja och sedan upptäckt hur varmt det blir när solen tittar fram? Med hjälp av den erfarenheten är det säkert tydligt att mörka material värms upp mer av solens strålar än ljusa material. Man säger att mörka material ”tar till sig”, eller absorberar, en större andel av den strålning som solen sänder ut i form av ljus. Det som inte absorberas kan istälHuman population on Earth is increasing and is projected to continue increasing for many years to come. Most of the increase will probably occur in cities and the extent of urban areas will increase with it. As cities grow larger and new cities are built, the many and diverse climatic effects of urbanization will become more evident. A specific climatic effect of urbanization which has not receive