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Background: ECG abnormalities have been linked to adverse changes in right ventricular (RV) morphology and poor clinical outcomes in repaired Tetralogy of Fallot (rTOF). Our aim was to describe how ECG changes progress in early and intermediate follow-up and whether types of surgical strategy at the time of primary repair affected these changes. Methods: We studied patients with rTOF born 2000–201
The inadequacy of public financing mechanisms for sustainable development andclimate action is increasingly evident. The focus has shifted towards private sector financing mechanisms to bridge these financing gaps. This study analyses the Green, Social, Sustainability and Sustainability-linked (GSSS) bonds, considered as the quintessential private sector financing instruments and projected to lead
Aims: To evaluate the cost-effectiveness of bimekizumab, an inhibitor of IL-17F and IL-17A, against biologic and targeted synthetic disease-modifying antirheumatic drugs (DMARD) for psoriatic arthritis (PsA) from the Swedish healthcare system perspective. Materials and methods: A Markov model was developed to simulate the clinical pathway of biologic [b] DMARD-naïve or tumor necrosis factor inhibi
Emulsification is the process of making stable mixture of two or more immiscible substances (typically oil and water). The product of this process, the emulsion, is found in various applications and industries such as food (milk and other dairy products, non-dairy alternatives, mayonnaise, salad dressing), cosmetics and pharmaceuticals (creams, lotions, intravenous medications), chemical (paints,
A compressor map with variations in component level characteristics is introduced. This novel approach to plot component level characteristics identify and give context to the critical design parameters such as flow angles, pressure coefficients, and loss coefficients across the entire compressor map along with the conventional performance parameters. Compressor design involves a significant amoun
Bat ultrasound analysis has been around for several decades and it is one of the most important tools in studies of bat ecology. Discrimination between species is based on intra-specific features of echolocation calls. Identification of species and genera in audio files can be attempted either manually or through software which performs a fully automated discrimination between species. However, si
Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance over standard approaches of PRS construction. Here, we implemented computationally efficient, penalized, logistic regression models (lasso, elastic net, stepwise) to individ
OBJECTIVE: To clarify, using an extended adoption design, the sources of parent-offspring transmission for anxiety disorder (AD) and its major subforms and their familial cross-generational relationship with major depression (MD). METHODS: Offspring (born 1960-1992) and their parents, from six family types (intact, not-lived-with biological father or mother, lived-with step-father or step-mother,
Materials of ionic crystals are ubiquitous in industrial chemistry.For example, materials such as cerium dioixde (CeO2) are used in both self-cleaning ovens and to clean exhaust fumes from cars.Other materials, such as titanium dioixde (TiO2) has been used in the solar-cell industry.So-called garnets are used in several lasers.In common for all of these areas of application, is that they are depen
Background: Optimal oxygen targets in patients resuscitated after cardiac arrest are uncertain. The primary aim of this study was to describe the values of partial pressure of oxygen values (PaO2) and the episodes of hypoxemia and hyperoxemia occurring within the first 72 h of mechanical ventilation in out of hospital cardiac arrest (OHCA) patients. The secondary aim was to evaluate the associatio
Background: Sugarcane is an attractive feedstock for ethanol production, especially if the lignocellulosic fraction can also be treated in second generation (2G) ethanol plants. However, the profitability of 2G ethanol is affected by the processing conditions, operating costs and market prices. This study focuses on the minimum ethanol selling price (MESP) and maximum profitability of ethanol prod
Popular Abstract in English The word “combustion” describes a number of physical and chemical processes, whose common characteristic is an interaction between fuel and oxygen and their subsequent transformation into products, such as CO2 and water. Even though the process is often described as a single chemical reaction between fuel and oxygen, in reality, their chemical transformation requires maThe laminar burning velocity and the flame structure are common targets for combustion studies aimed at detailed kinetic model development. In the present work, fuels relevant to hydrogen combustion were considered. The laminar burning velocity of rich and lean hydrogen flames was studied experimentally and numerically, including its pressure dependence in rich mixtures and temperature dependence
The detailed structural and mechanical properties of a tetraoleoyl cardiolipin (TOCL) bilayer were determined using neutron spin echo (NSE) spectroscopy, small angle neutron and X-ray scattering (SANS and SAXS, respectively), and molecular dynamics (MD) simulations. We used MD simulations to develop a scattering density profile (SDP) model, which was then utilized to jointly refine SANS and SAXS d
Popular Abstract in Swedish Antalet äldre i befolkningen ökar i förhållande till andra åldersgrupper. Detta beskrivs medföra en ekonomisk utmaning för samhället och att fler äldre behöver skjuta upp sin ålderspension. Avhandlingen bygger på fyra studier med det övergripande syftet att bidra till ökad kunskap om faktorer som medverkar till ett förlängt alternativt förkortat arbetsliv bland personerIn most of the industrialised world, the proportion of older and retired people in the population is continuously increasing. This will have budgetary implications for maintaining the welfare state, because the active working section of the population must fund the non-active and old population. Aim: The overall aim of this thesis was to obtain knowledge about older workers’ work and life situatio
To identify prognostic factors after hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT). We retrospectively reviewed the combined experience at Toronto General Hospital and Hospital Vall d'Hebron managing HCC recurrence after LT (n = 121) between 2000 and 2012. We analyzed prognostic factors by uni- and multi-variate analysis. Median follow-up from LT was 29.5 (range 2-129.
Popular Abstract in Swedish Avhandlingen omfattar tillverkning av metallmatris kompositer, MMC, baserade främst på aluminium legeringar. Nya metoder är utvecklade och undersökta där infiltrationen av fiberstrukturer av aluminiumoxid är stimulerad av mekaniska vågor vid frekvenser upp till 7 kHz. Vågrörelserna är genererade med nyutvecklad hög-magnetostriktiv aktuatorteknik. Målet med studierna harThe implementation of highly magnetostrictive wave-actuator techniques in preform infiltration processes for metal-matrix composite production is described. Metal matrix materials require additional methods to handle the content, shape and position of the ceramic reinforcements, which are not required for metal alloy casting. Commercial fabrication of advanced metal matrix composite products has
With the exponential growth of the World Wide Web, automated subject classification has become a major research issue. Organizing web pages into a hierarchical structure for subject browsing has been gaining more recognition as an important tool in information-seeking processes.The most frequent approach to automated classification is machine learning. It, however, requires training documents and
Background: The Epidermal Growth Factor Receptor (EGFR) activated Extracellular-signal Regulated Kinase (ERK) pathway is a critical cell signalling pathway that relays the signal for a cell to proliferate from the plasma membrane to the nucleus. Deregulation of the EGFR/ERK pathway due to alterations affecting the expression or function of a number of pathway components has long been associated wi
Wireless adhoc networks transmit information from a source to a destination via multiple hops in order to save energy and, thus, increase the lifetime of battery-operated nodes. The energy savings can be especially significant in cooperative transmission schemes, where several nodes cooperate during one hop to forward the information to the next node along a route to the destination. Finding the b
