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District heating and cooling systems offer a cost-effective and secure supply of heating and cooling to connected buildings. They are widely recognised as a key solution to decarbonise the building sector due to their high potential of integrating renewable energy sources. The systems traditionally involved generating heating and cooling centrally with distribution through separate pipes before de
During the 1980s the word ’postmodernism’ was inserted into the dicourse of Swedish literature in a curious way. Even though both writers and critics found the word bewildering – or deemed it a buzzword devoid of meaning – it sparked fierce debates. Despite this, and despite the fact that few wanted to be associated with the word, it has become common to describe the 1980s as the era of Swedish li
In recent decades, information technology has enjoyed an ever-increasing degree of influence upon society. The use of technology has proliferated, bleeding into all human activities, and now extends into the most private activities of individuals. Unfortunately the perpetrators of serious crimes have not missed the revolution. Technology has marked off many working terrains including that of serio
In their quest for a more efficient and effective utilization of the resources allocated to engineering design projects, and thus to the overall product development project from which the current design task(s) originate, an increasing number of companies allow engineering designers to perform Computer-Based Design Analysis (CBDA) on their own – CBDA is here confined to quantitative analyses using
Popular Abstract in Swedish Trådlösa system som använder elektromagnetisk strålning, även kallat radio kort och gott, har fått ett enormt genomslag i våra liv. Radio används överallt: telefoni, GPS, mobilt bredband och TV är tillämpningar som vi som privatpersoner lätt kommer i kontakt med men även till radar, magnetisk resonanstomografi och andra avbildande system. Speciellt datakommunikation i mThis thesis investigates the opportunity of wireless multi-gigabit per second communication at the millimeter-wave (mmW) frequencies around 60 GHz by using impulse radio and nanoelectronics. Today most wireless communication take place in the microwave region, where several different systems and applications are crowding the narrow-band channels. Complicated schemes are applied in order to avoid i
Land use change from agricultural intensification has been highlighted as one of the major drivers of global declines in insects, reducing species diversity and abundance and shifting community composition towards generalist species. However, it remains a challenge to determine how land use change impacts the genetic diversity of species and populations even if this diversity is vital to their lon
2641Background: BI-1808 is an IgG1 mAb that target TNFR2 by blocking interaction of TNFR2 with ligand TNF-α, confers FcγR-dependent depletion of Treg and mediates expansion of intratumoral CD8+ T cells. Upon co-administration of murine surrogate antibodies targeting TNFR2 and anti-PD-1 to immunocompetent tumor-bearing mice with partial sensitivity to checkpoint blockade, complete cures were observ
Blood biomarkers have the potential to revolutionize Alzheimer's disease diagnosis, offering advantages over CSF and PET due to their accessibility, scalability and cost-effectiveness. This study evaluated the effectiveness of individual plasma biomarkers, such as phosphorylated Tau (pTau) 217, as well as biomarker combinations, with a focus on the pTau 217/β-Amyloid (Aβ) 1–42 ratio to predict amy
Objective: To develop machine-learning models that incorporate clinical information and radiomics features extracted from ultrasound images to distinguish uterine sarcomas from leiomyomas. Methods: This retrospective, multicenter, pilot case–control study included 200 patients (100 with a uterine sarcoma and 100 with a usual-type leiomyoma, i.e. including no benign leiomyoma variants) who underwen
BACKGROUND AND OBJECTIVES: Subjective cognitive decline (SCD) is a well-recognized risk state for developing mild cognitive impairment (MCI) and dementia. Optimal risk stratification for early interventions and clinical trial selection remains challenging. This study evaluates progression risk across multimodal biomarker profiles in SCD.METHODS: We conducted a longitudinal observational study incl
Idag lever vi en globaliserad värld där varor, tjänster och personer rör sig över större avstånd på ett allt enklare och snabbare sätt. Detta har resulterat i att fler företag har valt att etablerat sig internationellt och i allt större utsträckning strävar efter att etablera sig och verka globalt. När företag verkar i flera länder är en av konsekvenserna att företagen måste efterfölja lagar och rToday we live in a globalized world where goods, services and people can move easily over wide distances smoother and faster for each day. This has resulted in an increasing number of companies striving to establish and operate globally. One of the consequences when companies establishes worldwide is that they must comply with laws and regulations in the countries where they choose to establish. T
Denna framställning syftar till att lyfta fram gruppen barn som anhöriga i rampljuset. Som led i detta kommer det att redogöras för hur barns väg från objekt till subjekt påverkat barns rättigheter och särskilt rätten att få information stöd och hjälp vid förälders missbruk eller psykisk ohälsa. För att kunna ge en mer fullständig bild av detta problem har även tillämpningen av dessa eventuella reThis essay seeks to bring children with parents suffering from addiction problems or mental illnesses to the public attention. In order to do this I have to examine how the view of children within the legal system has changed, from being an object to being a subject, and how this has affected children’s rights to receive information, support and help when one or both parents suffer from addiction
Problem Discussion: Nissan Diesel became a part of the Volvo Group in the end of March, 2007. A year has passed and the integration process is making progress but it is perceived to lack some momentum. Our sponsor would like to understand if there are any potential barriers to the integration process. (Haspeslagh, et al., 1991) and (Pablo, 1994) presents two different sets of determinants that can
The general rule in EC law is that a holder of an intellectual property right is not obliged to license the use of that right to others. However, situations exist where intellectual property rights suffer some limitations because of the prevalence of other conflicting interests. A dominant firm can, as the holder of an intellectual property right, be forced to grant a license to one or more undert
Flyktingströmmen 2015 medförde en stor ökning av antalet asylsökande till Sverige, varav många anförde att de var ensamkommande minderåriga. Inte sällan ifrågasatte myndigheterna sökandenas åldrar, vilket medförde ett behov av åldersbedömningar. Regeringen gav då i uppdrag att skyndsamt utveckla och påbörja medicinska åldersbedömningar, och en metod för detta utvecklades hastigt. Enbart under 2017In 2015, Sweden saw a large influx of asylum-seekers into the country, many of whom claimed to be unaccompanied minor. Without personal documents to attest their age, the authorities often doubted these claims of minority, prompting a need for age assessment. The government called for medical age assessments to be developed and introduced and a method for medical age assessment was hastily develop
Förtätning och byggande i urbana miljöer innebär stora utmaningar för alla inblandade parter, stadens invånare, verksamheter och besökare. Låg effektivitet- och produktivitetsutveckling i byggbranschen, tillsammans med ökade miljökrav är ett par av de främsta utmaningarna. Krav på effektiv ytanvändning förutsätter en välfungerande, effektiv logistik och materialhantering, med minimal påverkan på dDensification of cities and construction in urban environments poses major challenges for all parties involved, the city's residents, businesses and visitors. Low efficiency and productivity development in the construction industry, together with increased environmental requirements are a few of the main challenges. Requirements for efficient use of surface demands efficient logistics and mate
I samband med att företag drabbas av arbetsbrist aktualiseras arbetsgivarens skyldighet att utreda möjligheterna att erbjuda den eller de berörda arbetstagarna omplaceringar till andra befattningar i enlighet med 7 § 2 st. LAS. Denna omplaceringsskyldighet är tvingande oavsett företagets storlek och syftar till att så långt det går undvika friställningar av arbetstagare. Av lagtexten framgår att eWhen companies are suffering from labor shortages, the employer’s obligation to investigate the possibility of offering the affected employee or employees other positions in accordance with section 7 second paragraph is raised. This relocation obligation is mandatory regardless of the size of the company and aims to avoid employee layoffs as far as possible. It is clear from the legal text that a
Under de senaste 10 åren har cirka en miljon människor sökt asyl i Sverige varav hela 163 000 enbart under 2015 när den stora flyktingvågen tog fart i världen. Detta satte stor press på Sveriges hantering av flyktingar och framförallt kommunernas bostadsförsörjningsansvar. Den 1 mars 2016 införde regeringen beslutet att kommunerna är skyldiga att ta emot ett visst antal nyanlända i syfte att ge deDuring the last 10 years approximately one million people have applied for asylum in Sweden and 163 000 only during the big stream of immigrants in 2015. This put a huge pressure on the Swedish management of immigrants and the housing for this group of people. The 1st of March 2016 the Swedish Government introduced a law where the Swedish municipalities are obligated to receive a certain number of
