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Background: SARS-CoV-2 mRNA vaccination has been associated with both side effects and a reduction in COVID-related complaints due to the decrease in COVID-19 incidence. We aimed to investigate if individuals who received three doses of SARS-CoV-2 mRNA vaccines had a lower incidence of (a) medical complaints and (b) COVID-19-related medical complaints, both as seen in primary care, when compared t
BACKGROUND: Musculoskeletal disorders include more than 150 different conditions affecting joints, muscles, bones, ligaments, tendons, and the spine. To capture all health loss from death and disability due to musculoskeletal disorders, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) includes a residual musculoskeletal category for conditions other than osteoarthritis, rheuma
IMPORTANCE Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. For patients who reject full-time bracing, the effects of alternative, conservative interventions are unknown. OBJECTIVE To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activ
Heart failure (HF) is a leading cause of death and disability globally. HF represents the common end- stage of most heart conditions, during which the heart is unable to generate sufficient output of blood for the metabolic demands of the body and intracardiac pressures increase. Different heart diseases display specific molecular pathophysiologies, but common pathways are also present that drive
Background: Homologous recombination (HR) deficiency (HRD) is prevalent in ovarian, prostate, and specific subgroups of breast cancer, particularly triple-negative breast cancer (TNBC). Tumor HRD status can be inferred through DNA-based, RNA-based, functional, or image-based approaches. A comprehensive evaluation of the concordance and discordance among HRD prediction methods derived from these di
Popular Abstract in Swedish Traditionellt har olika aspekter av ett ekosystem studerats var för sig inom olika ekologiska discipliner såsom växtfysiologi, forskning om hur organismer interagerar med varandra och forskning om hur ekosystem som helhet beter sig. Denna avhandling innehåller exempel på att simulationsmodeller gör det möjligt att undersöka hur de olika processerna samverkar för att forPlant physiology, population dynamics and the structure and functioning of ecosystems are closely interrelated. However, these processes are often investigated independently within different subdisciplines of ecology. Mechanistic models of ecosystem structure and functioning combine representations of processes operating at a range of scales and levels of organisation, providing a tool for the des
Monday may 3 Tuesday May 4 08.30 Registration & tea/coffee/fruits outside the lecture hall 09.00 Sture Forsén ”Introduction and practical information” 09.15 SESSION I: The Dynamic Epigenome • Stephan Beck “To be announced” • Dirk Schübeler ”Regulation by repression: DNA methylation and chromatin during cel- lular differentiation” 10.45-11.15 Tea/Coffee • Kristian Helin “The role of Polycomb grou
https://www.pi.lu.se/sites/pi.lu.se/files/epigenetics_symposium_program.pdf - 2026-07-17
Dosimetry Relativdosimetri Crister Ceberg Medical Radiation Physics Lund University Sweden Reference geometry Treatment unit Ion chamber => monitor units, UR Measurement point => absorbed dose, DR Water tank 𝐷𝑅 = 𝐷𝑅 𝑈𝑅 Treatment geometry • Distance from source, f • Collimator setting, c • Treatment depth in patient, z Relative dosimetry Reference geometry Treatment geometry fR f DDR z zR ccR
https://www.msf.lu.se/sites/msf.lu.se/files/4._relativdosimetri.pdf - 2026-07-17
Nematode-trapping fungi are ubiquitous, soil-living organisms with the ability to infect and kill nematodes. These fungi have developed specialized infection structures for the capture of nematodes. Many nematode species are parasites on plants and animals, which have resulted in an interest to use nematode-trapping fungi as biological control agents. Through bioinformatics approaches, I have used
Popular Abstract in Swedish Avhandlingen behandlar ett område beläget cirka 65 km nordväst om Rom, och är en detalj- studie av områdets arkeologi, i syfte att belysa förhållandet mellan en tätbebyggelse, Luni sul Mignone och dess kringland. Grundtemat är förändringar i demografi och bebyggelse över tiden, som dessa kan ses i olika slags materiella lämningar. Även andra aspekter än de rent demografThis thesis is an archaeological study of a small region in northern Latium and the diachronical relationship between a nucleated settlement and its rural landscape. The work has a twofold basis: a review of earlier research concerning the settlement Luni sul Mignone in the light of more recent research, and a survey conducted by the present author of the territory of Luni. This survey and its res
Popular Abstract in Swedish Sandstäpp är ett starkt hotat växtsamhälle i Sverige som består av många specialiserade och hotade arter som t.ex. sandnejlika, tofsäxing och sandliljor. Exempel på hur en sandstäpp kan se ut hittas i Figur 1 i den Engelska sammanfattningen. Sandstäpp finns på sandig mark med kalk i ytjorden och ett lågt näringsinnehåll. Den karaktäriseras av ett uppbrutet växttäcke som
In this thesis the connection between coherence and reliability is investigated. The question may be phrased as follows: does the fact that a set of testimonies is coherent imply that the witnesses who have reported these testimonies are reliable? The same question may also be expressed in terms of beliefs: does the fact that a set of beliefs is coherent imply that the beliefs were reliably produc
The aim of the work presented in this thesis is the improvement of xylose fermentation performance of recombinant Saccharomyces cerevisiae strains expressing XYL1 and XYL2 from Pichia stipitis, encoding xylose reductase (XR) and xylitol dehydrogenase (XDH). A recombinant strain of S. cerevisiae, fermenting both xylose and glucose to ethanol could decrease the production cost of ethanol from ligno-
Ectomycorrhizae is a mutualistic association between roots of woody plants and a diverse range of soil fungi. The fungi exchange soil derived mineral nutrients for photosynthetic sugars from the host plant. The mycorrhizal symbioses are commonly found in all forest ecosystems and have a major ecological and economical importance. I have used comparative genomics, DNA microarrays and computational
Restriction Endonuclease Analysis (REA) was used to characterize strains of Lactobacillus plantarum, Lb. pentosus, and Lb. reuteri. This method was shown to be a powerful tool for separation at the species and strain level. RAPD analysis of raw cell abstracts was used to characterize strains of Lb. plantarum. This method was shown to be useful for separation of most strains, and the results were o
Popular Abstract in Swedish Vårt immunsystem har utvecklats för att skydda våra vävnader och organ vid infektioner, cancerväxt och andra skador. Immunsystemet utgörs av en mängd olika celltyper som på olika sätt specifikt, främst genom uttryck av receptorer på cellytan, reagerar på främmande strukturer, från t ex patogener eller tumör celler eller andra substanser som signalerar stress eller fara.This thesis is based on three original papers with the overall aim to study the mechanisms of induction and function of Foxp3+CD4+CD25+ regulatory T cells. Regulatory T cells induce down-modulation of costimulatory molecules CD80 and CD86 on dendritic cells in vitro. In the first study we further show that the extent of down-modulation is functionally significant since regulatory T cell condition
Popular Abstract in Swedish En av dagens största utmaningar är de stadigt ökande utsläppen av förorenande avgaser och drivhusgaser. Den största delen av dessa föroreningar kommer från förbränningsanläggningar och fordon. För att kunna minska utsläppen måste man förstå förbränningsprocesserna, och hur man kan kontrollera förbränningen. Utmaningen är att förbränningprocesser är mycket komplexa. Det To deal with complex physical and chemical processes in reactive systems, such as combustion processes, it is necessary to find methods that simplify modelling in such a way that it becomes both more comprehensible and practically useful. In the work reported here a method for automatically reducing chemical reaction mechanisms has been developed for use in computer simulations of various combusti
In this thesis a simulation model is presented that enables a comparison of different hybrid topologies, with respect to fuel consumption, emissions and performance. The obtained results stress the properties of the different topologies and form a foundation for the choice of hybrid topology. The simulation models included in this thesis are the result of collaboration with Petter Strandh at the D
