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BACKGROUND: Angiogenic activity defined by microvessel density or measurement of vascular endothelial growth factor is a key process under physiological and malignant conditions in steroid hormone responding organs. The aim of this study was to relate microvessel density (MVD) in primary breast cancer to reproductive data and use of exogenous hormones. MATERIAL AND METHODS: MVD was calculated retr
This article develops the theory of laminar dispersion in finite-length channel flows at high Péclet numbers, completing the classical Taylor-Aris theory which applies for long-term, long-distance properties. It is shown, by means of scaling analysis and invariant reformulation of the moment equations, that solute dispersion in finite length channels is characterized by the occurrence of a new reg
Introduction: Looking into the future is difficult and sometimes hazardous. A reliable look into haemophilia treatment in 2030 should be based on history and contemporary progress as well as dilemmas. Today, the issue of inhibitors overshadows the entire haemophilia community together with lack of treatment for large parts of the world's persons with haemophilia. Aims: The aim of this paper was to
Collective identities of the Self (or Ego) vs. the Other are not only conveyed in and between cultures through verbal discourse but also through pictures. Such cultural constructions are often established and consolidated by storytelling, where, briefly put, events or situations are temporally ordered. Pictures and visual artworks may be powerful narrative resources for establishing and consolidat
Scatterer size estimation is useful when characterizing tissue using ultrasound. In all previous studies on scatterer size, the estimations are performed in the frequency domain and are thus subjected to a trade off in time-frequency resolution. This study focused on the feasibility of estimating scatterer size in the time domain using only the ultrasound center frequency, assuming a Gaussian-shap
The LHCb system requires high efficiency muon detection into LHC bunch crossing: 95% into a 25 ns time window. To reach such efficiency many parameters of the detector readout apparatus have to be calibrated and adjusted and its channels must be aligned in time. In addition, essential characteristics must be monitored to guarantee a good working condition of the apparatus (to avoid loss of efficie
The majority of microarray studies evaluate gene ex- pression differences between various specimens or con- ditions. However, the causes of this variability often re- main unknown. Our aim is to identify underlying causes of these patterns, a process that would eventually enable a mechanistic understanding of the deregulation of gene expression in cancer. The procedure consists of three phases: pr
Dipeptidyl peptidase 4 (DPP-4) inhibitors are now being clinically utilized as glucose-lowering medications for the treatment of type 2 diabetes. Their widespread use and effective glucose-lowering properties have led to great interest in the mechanism of action of this class of drug. Although it has been well accepted that DPP-4 inhibitors lower glucose in part by increasing postprandial insulin
This study systematically evaluated the psychological reactions of a non-clinical population to the October 1989 Bay Area earthquake. Within a week of the earthquake, a checklist of anxiety and dissociative symptoms was administered to a representative sample of approximately 100 graduate students and faculty members from two different institutions in the Bay Area. A follow-up study was conducted
Parliamentary debates provide an arena where Members of Parliament (MPs) present, challenge, or defend public policies. However, the “plenary bottleneck” allows the party leadership to decide who participates in a debate. We argue that in this decision the timing of a debate matters: in proximity of elections, the leadership should be concerned with maintaining its brand name and therefore restric
Motivated by school admission systems used in, e.g., Turkey and Sweden, this paper investigates a sequential two-stage admission system with public and private schools. To perform the analysis, relevant axioms and equilibrium notions need to be tailored for the considered dynamic setting. In particular, a notion of truthfulness, referred to as straightforwardness, is introduced. In sharp contrast
I Sverige inträffar runt 5500 bränder i bostäder årligen och i ca 80 av dessa bränder omkommer en eller flera personer. Det finns en långsamt nedåtgående trend för antalet omkomna i landet och världen, men nedgången är långsam och det finns inte heller några tydliga indikationer på vad denna nedgång kan beror på.Syftet med detta arbete är att studera olika byggnadstekniska faktorer i bostäder där The purpose of this work is to study fatal residential fires and see if they are correlated with any specific building characteristics. In this report, data on fatal fires are paired with data about the properties where the fires occurred. The analysis has shown that apartment buildings are overrepresented among properties with fatal fires compared to single-family units and agricultural units. It
Deep eutectic solvents have shown the ability to promote the self-assembly of surfactants in solution. However, some differences have been found compared with self-assembly in pure water and other polar organic solvents. The behaviour of alkyltrimethylammonium bromides in choline chloride:glycerol deep eutectic solvent has been studied by means of surface tension, X-ray and neutron reflectivity an
