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Abstract in German Die CEAP-Klassifizierung für chronische Venenleiden wurde 1994 durch ein internationales Ad-hoc-Komitee des American Venous Forum entwickelt, durch die Society for Vascular Surgery unterstützt und 1995 in die „Reporting Standards in Venous Disease“ inkorporiert. Inzwischen benutzen die meisten publizierten klinischen Arbeiten das CEAPSystem, ganz oder in Teilen. Um die KlassifizThe CEAP classification for chronic venous disorders (CVD) was developed in 1994 by an international ad hoc committee of the American Venous Forum, endorsed by the Society for Vascular Surgery, and incorporated into "Reporting Standards in Venous Disease" in 1995. Today most published clinical papers use all or portions of CEAP. Rather than have it stand as a static classification system, an ad ho
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We have started a systematic investigation of the radiative properties of the elements of the sixth row of the periodic table. Using a combination of experimental radiative lifetimes obtained with the time-resolved laser-induced fluorescence (LIF) technique and of theoretical branching fractions (BF) calculated with a HFR approach taking configuration interaction and core-polarization effects into
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We consider the capacity of multiple-input multiple-output systems with. reduced complexity. One link-end uses all available antennas, while the other chooses the L out of N antennas that maximize capacity. We derive an upper bound on the capacity that can be expressed as the sum of the logarithms of ordered chi-square-distributed variables. This bound is then evaluated analytically and compared t
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We establish a higher-dimensional version of multifractal analysis for several classes of hyperbolic dynamical systems. This means that we consider multifractal decompositions which are associated to multi-dimensional parameters. In particular, we obtain a conditional variational principle, which shows that the topological entropy of the level sets of pointwise dimensions, local entropies, and Lya
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The idea of the Gesamtkunstwerk and the belief in the kinship of the arts were passed on from late romanticism to many of the modernist movements in the first decades of the twentieth century. Thus artists and film-makers wished to accomplish a fusion that transferred the achievements of non-figurative art to the new film medium, swayed by the constraints of realist story-telling. But abstract fil
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Adult growth hormone deficiency (GHD) is a multifactorial disorder in which pituitary dysfunction associated with pituitary adenomas or their treatment plays a major role. The introduction of recombinant growth hormone (GH) for the treatment of GHD has opened up new treatment avenues but has also raised concerns about possible untoward long-term metabolic effects of GH, such as the potential effec
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A charging unit for unipolar charging of cloud and fog droplets has been developed and calibrated regarding ion current, angular distribution of ions, mean droplet charge and droplet charge distribution. The charger is part of the droplet aerosol analyser, which is an instrument used for characterisation of droplets and interstitial particles in atmospheric clouds and fog. Three different calibrat
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Diabetes is caused by an absolute (type 1) or relative (type 2) deficiency of insulin-producing beta cells. We have disrupted expression of the mitochondrial protein frataxin selectively in pancreatic beta cells. Mice were born healthy but subsequently developed impaired glucose tolerance progressing to overt diabetes mellitus. These observations were explained by impairment of insulin secretion d
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Clopidogrel is an important and widely used antiplatelet drug; only the (S)-isomer is the active biological enantiomer. The industrial production of the active enantiomer involves resolution of the racemic compound using stoichiometric amounts of L-camphor sulphonic acid and crystallization in a process using large amounts of solvent. In the present study, the possibility of enzyme catalysed kinet
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We present a comparison of two-dimensional separation methods and how they affect the degree of coverage of protein expression in complex mixtures. We investigated the relative merits of various protein and peptide separations prior to acidic reversed-phase chromatography directly coupled to an ion trap mass spectrometer. The first dimensions investigated were density gradient organelle fractionat
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This study investigates agglomeration effects for classical music production in a wide range of cities for a global sample of composers born between 1750 and 1899. Theory suggests a trade-off between agglomeration economies (peer effects) and diseconomies (peer crowding). I test this hypothesis using historical data on composers and employ a unique instrumental variable - a measure of birth centra
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First, we study geometric variants of the standard set cover motivated by assignment of directional antenna and shipping with deadlines, providing the first known polynomial-time exact solutions. Next, we consider the following general (non-necessarily geometric) capacitated set cover problem. There is given a set of elements with real weights and a family of sets of the elements. One can use a s
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In exploratory high-dimensional data analysis, local intrinsic dimension estimation can sometimes be used in order to discriminate between data sets sampled from different low-dimensional structures. Global intrinsic dimension estimators can in many cases be adapted to local estimation, but this leads to problems with high negative bias or high variance. We introduce a method that exploits the cur
