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Cytogenetic aberrations have been reported in 45,000 human neoplasms. Structural balanced rearrangements are associated with distinct tumor subtypes with remarkable specificity and have been essential for identifying genes involved in tumorigenesis. All balanced rearrangements that have been characterized molecularly act by deregulating a gene in one of the breakpoints or by creating a fusion gene
The generation of harmonics through a nonlinear mechanism driven by bunching at the fundamental has sparked interest as a path toward enhancing and extending the usefulness of an X-ray free-electron laser (FEL) facility. The sensitivity of the nonlinear harmonic generation to undulator imperfections, electron beam energy spread, peak current, and emittance is important in an evaluation of the proc
Parkinson's disease (PD) patients display motor symptoms, e.g. tremor, rigidity and bradykinesia, largely due to a dramatic loss of dopaminergic neurons in the substantia nigra. Grafts of human embryonic dopamine neurons can survive in the striatum and reduce several of the motor symptoms. Several lines of evidence suggest that a crucial threshold of surviving dopaminergic neurons must be exceeded
In this thesis three general problems concerning construction of evolutionary trees are considered. Algorithms for the problems are presented and the complexity of the problems is investigated. The thesis consists of three corresponding parts. The first part is devoted to the problem of constructing evolutionary trees in the experiment model. Different algorithms for the problem are given, includ
In this article, the structure of two-sided ideals in the q-deformed Heisenberg algebras defined by the q-deformed Heisenberg canonical commutation relation AB-qBA=I is investigated. We show that these algebras are simple if and only if q = 1. For q not equal 1, 0 we present an infinite descending chain of non-trivial two-sided ideals, thus deducing by explicit construction that the q-deformed Hei
A simplified method using centrifugation and microcentrifuge tubes instead of filtration to measure bacterial activity using thymidine or leucine incorporation, originally used in aquatic habitats, has been adapted for soil. A final step employing hot NaOH to solubilize macromolecules before adding scintillation fluid was necessary to achieve the same incorporation rates as those in the filtration
In this article, we turn first to a brief discussion of feminist contributions in the field of security, defense, and collective identity, and then argue that Swedish nationalism is tied to a particular form of collective identity formation through the practice of conscription. Drawing on Elshtain's notions of 'just warriors' and 'beautiful souls', we go on to spell out how women, historically, ha
In this paper, we present a cluster based analysis of an outdoor-to-indoor Multiple-Input Multiple-Output (MIMO) measurement campaign, and extract model parameters for the COST273 channel model. The measurements were performed at 5.2 GHz for 159 measurement locations in an office building. Multipath component (MPC) parameters have been extracted for these positions using a high-resolution algorith
This paper presents a study where a market-driven requirements management process is simulated. In market-driven software development, generic software packages are released to a market with many customers. New requirements are continuously issued, and the objective of the requirements management process is to elicit, manage, and prioritize the requirements. In the presented study, a specific requ
A parallel finite element approach for analyzing micromechanical problems with periodic unit cells is discussed. The method uses a direct solution strategy so that general periodic boundary conditions can be treated using a two-step domain decomposition strategy. The speedup results show a good performance of the method on coarse-grained problems, i.e. for cases where the computational work done o
The development and transplantation of autologous cells derived from nuclear transfer embryonic stem cell (NT-ESC) lines to treat patients suffering from disease has been termed therapeutic cloning. Human NT is still a developing field, with further research required to improve somatic cell NT and human embryonic stem cell differentiation to deliver safe and effective cell replacement therapies. F
