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To investigate a putative involvement of protein kinase C (PKC) isoforms in supporting neuroblastoma cell proliferation, SK-N-BE(2) neuroblastoma cells were transfected with expression vectors coding for the C2 and V5 regions from different PKC isoforms. These structures have been suggested to inhibit the activity of their corresponding PKC isoform. The PKC fragments were fused to enhanced green f

Cross-sectional studies have reported strong correlations between plasma levels of complement C3, insulin, and glucose. This prospective study explored whether elevated levels of C3, C4, and other inflammation-sensitive plasma proteins (ISPs; fibrinogen, orosomucoid, α1-antitrypsin, haptoglobin, and ceruloplasmin) are associated with the development of diabetes. Plasma proteins were measured in 2,

The incretin - glucose-dependent insulinotropic polypeptide (GIP) - and the pro-inflammatory cytokine osteopontin are known to have important roles in the regulation of adipose tissue functions. In this work we show that GIP stimulates lipogenesis and osteopontin expression in primary adipocytes. The GIP-induced increase in osteopontin expression was inhibited by the NFAT (the transcription factor

We present the results of the measurements of the detection efficiency for a 4.7 angstrom neutron beam incident upon a detector incorporating a stack of up to five MultiWire Proportional Counters (MWPC) with Boron-coated cathodes. The cathodes were made of Aluminum and had a surface exhibiting millimeter-deep V-shaped grooves of 45 degrees, upon which the thin Boron film was deposited by DC magnet

Bees are mostly active during the daytime, but nocturnality has been reported in some bee families. We studied temporal flight activity in three species of carpenter bees (genus Xylocopa) in relation to light intensities. X. leucothorax is diurnal, X. tenuiscapa is largely diurnal being only occasionally crepuscular, while X. tranquebarica is truly nocturnal. Occasional forays into dim light by X.

AIM: The aim of this study was to investigate early changes in uptake of 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) in vivo and in vitro in a squamous-cell carcinoma (SCC) cell line originating from a human head and neck SCC during cytotoxic therapy with respect to metabolism in tumor cells and in surrounding stromal tissue. MATERIALS AND METHODS: In 60 nude mice with xenografted SCC, 50 animals were

Song is a sexually selected trait in many bird species and has been suggested to function as a signal of a male's health and parasite resistance. Here we present an experimental field study on the long-term effects of parasite exposure early in life on adult bird song. We exposed nestling great tits (Parus major) to ectoparasitic hen fleas (Ceratophyllus gallinae) and on their recruitment into the

Broadband circuit models for electric machines are effective means to understand, predict, and control the phenomenon of conducted Electromagnetic Interference (EMI) from immunity/susceptibility perspective. These models should cover the capacitive and inductive coupling behavior of the component along the frequency band of interest. The circuit models when used under generic SPICE simulation soft

Objective. The incidence of prostate cancer in Sweden is increasing rapidly, as is treatment with curative intent. Radical prostatectomy (RP) is currently commonly performed, either within or outside large high-volume centres. The aim of this study was to assess the 30-day mortality rate after RP in Sweden. Material and methods. In this nationwide population-based study, all men diagnosed with loc

Early vision is the process occurring before any semantic interpretation of an image takes place. Motion estimation, object segmentation and detection are all parts of early vision, but recognition is not. Many of these tasks are formulated as optimization problems and one of the key factors for the success of recent methods is that they seek to compute globally optimal solutions. This thesis is c

Aims. We present line identifications in the 1700 to 10 400 angstrom region for the Weigelt blobs B and D, located 0.'' 1 to 0 ''.3 NNW of Eta Carinae. The aim of this work is to characterize the behavior of these luminous, dense gas blobs in response to the broad highstate and the short low-state of. Carinae during its 5.54-year spectroscopic period. Methods. The spectra were recorded in a low st

This report covers the project period from 1.4.2003 to 31.08.2005. Project organisation, administration including the accounts, and the work carried out are reported. Besides, suggestions for copyright are put forward together with plans for dissemination activities and need for further research. The NAME was developed by the project group, consisting of all partners who have all contributed in an