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Introduction: Magnetic skyrmions hold great promise for realizing compact and stable memory devices that can be manipulated at very low energy costs via electronic current densities. Methods: In this work, we extend a recently introduced method to describe classical skyrmion textures coupled to dynamical itinerant electrons. In this scheme, the electron dynamics is described via nonequilibrium Gre

Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C-C chemokine receptor 3 (CCR3) is dramatically upregulated during osteoclastogenesis, but the role of CCR3 in osteoclast formation and bone remodeling in adult mice is unknown. Herein, we used bone marrow macrophages derived from adult male CCR3-proficient and CCR3-deficient m

The question of the rationality of conspiratorial belief divides philosophers into mainly two camps. The particularists believe that each conspiracy theory ought to be examined on its own merits. The generalist, by contrast, argues that there is something inherently suspect about conspiracy theories that makes belief in them irrational. Recent empirical findings indicate that conspiratorial thinki

For almost a century, the knock-resisting ability of a spark ignition fuel has been quantified with the RON and MON indications, conforming to the corresponding ASTM-D2699 and D2700 methods, respectively. These testing methods rely on specific pressure pickup technology that acts like a low-pass signal filter, thereby cutting off high frequency cylinder pressure information. Within a second-genera

Current precision cancer medicine is dependent on the analyses of a plethora of clinically relevant genomic aberrations. During the last decade, next-generation sequencing (NGS) has gradually replaced most other methods for precision cancer diagnostics, spanning from targeted tumor-informed assays and gene panel sequencing to global whole-genome and whole-transcriptome sequencing analyses. The shi

Developing efficient and robust computational models is essential to improve our understanding of protein solution behavior. This becomes particularly important to tackle the high-concentration regime. In this context, the main challenge is to put forward coarse-grained descriptions able to reduce the level of detail, while retaining key features and relevant information. In this work, we develop

Consumers want innovations that fulfil present and future needs and to be delighted! Hence the main objective of an innovation is to create value for the consumer/customer by a product, process, service or combinations, but is also important for manufacturers, suppliers and society, to promote growth, create new markets, answer new needs etc. The retailers now have the power in the supply - and va

An ethopoeia is an imagined speech assigned to a certain character. As a rhetorical exercise it is known from the progymnasmata of Theon, Hermogenes, Aphthonius and Nicolaus as well as contemporary rhetorical theorists. The purpose of the exercise was to teach the student the appropriate use of ethos and pathos for the assigned character. The paper will present the function of the ethopoeia as a p

This thesis describes interactions that are salt-promoted and mainly based on the hydrophobicity of proteins. A series of variants of the green fluorescent protein (GFP) was first constructed by site-directed mutagenesis. Several tags with various properties were then genetically fused to the N-terminus of GFP. The protein variants constructed had small characteristic differences in hydrophobicity

Popular Abstract in Swedish Allt levande består av celler. Cellen är livets allra minsta byggsten. Cellen har ett hölje som kallas cellmembran. Detta membran skiljer cellens inre som kallas cytosol från omvärlden. I detta cellmembran sitter olika protein inbäddade. Genom dessa protein kommunicerar och utbyter cellen ämnen med sin omgivning. Många av dessa protein är mål för läkemedel och är därför

INTERNATIONAL trade has become one of the pillars of the global economic system; an overlap between climate change policies and the multi-lateral trading system administered by the World Trade Organization (WTO) therefore seems inevitable. International trade affects climate change as it potentially increases economic activity that may in turn lead to increased greenhouse gas emissions. Conversely

Scholars studying international democratization have recently shown a greater interest in how elections in authoritarian contexts per se, could function as leverages for democratic improvement. This study contributes to this knowledge by asking; when do elections in electoral authoritarian regimes result in democratic consequences? Recognizing that elections can be a tool for democratic break

We recently reported behavioral improvements following intrastriatal transplantation of cryopreserved cultured human neuroteratocarcinoma-derived cells (hNT neurons) in rats with cerebral ischemia induced by occlusion of the middle cerebral artery. In the present study, the viability and survival of hNT neurons were evaluated immediately prior to the transplantation surgery and at 3 months post-tr

The neurotrophic effects of the BB isoform of platelet-derived growth factor (PDGF) on rat and human fetal mesencephalic dopaminergic neurons have been characterized in vitro. A dose-response analysis demonstrated maximal responses at 30 ng/ml of PDGF-BB. This concentration resulted in a marked increase in the survival and neurite outgrowth from rat and human tyrosine hydroxylase-(TH) positive, pr