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This paper establishes reserve price as an ethical necessity contrary to its popular interpretation as an instrument of revenue maximization. It provides an axiomatic justification to reserve pricing at Vickrey auction in single as well as multiple objects settings. In particular, it provides a topological interpretation of a reserve price as the infimum of the set of non-negative real numbers sat
Renal osteodystrophy alters metabolic activity and remodeling rate of bone and also may lead to different bone composition. The objective of this study was to characterize the composition of bone in high‐turnover renal osteodystrophy patients by means of Fourier transform infrared spectroscopic imaging (FTIRI). Iliac crest biopsies from healthy bone (n = 11) and patients with renal osteodystrophy
The main purpose of this dissertation is to describe how terminally ill patients experienced their situation, and what their views about the future were. Further, the experiences and attitudes of relatives of such patients, and of health care professionals, were also central. Focus was on existential issues, such as autonomy, meaning, guilt, relations, dignity, and communication. In the first pape
The increasing demand for solid biofuels, such as primary forest fuels, has highlighted the importance to consider that they, in contrast to fossil fuels are produced in dynamic ecosystems. Environmental effects of changes in ecosystem management policies, positive and negative, are not obvious. To that end, calculations of carbon budgets in single forest stands show that the carbon balance dramat
The chapter by definition focuses on Swedish research and treatment practice in the area of comorbiditity. Three “ethiological” lines of comorbidity is outlined. it thus seems warranted to look upon patients with a precipitating psychiatric diagnosis and a consequent problem of alcohol and/or substance abuse as one specific model/type (1). A second type representting the drug and substance depende
Popular Abstract in Swedish Signalen som registreras under ett arbets EKG prov kan innehålla viktig information rörande hjärtats kondition. De störningar som ofta uppträder i signalen kan dock försvåra en korrekt diagnos. I avhandlingens första del används tidsserie modeller för att skatta profilen, den del av signalen som härrör från hjärtats elektriska aktivitet. Målet med dessa metoder är att The analysis of the recorded electrical activity of the heart during an exercise test is a valuable method for investigating a patient's circulatory and respiratory system. But the disturbances that occurr during a test often make it difficult to interpret the signal in order to detect changes evoked by the increased workload and related to for instance coronary artery diseases. Suppression of dis
This thesis concerns the Large Eddy Simulation methodology and its application to predict complex turbulent flows at high Reynolds numbers, and at times also with high Mach numbers. The meaning of the word ?complex? refers both to the presence of complex flow phenomena and the, often, complex geometry of man-made devices restricting the flow. A fairly thorough evaluation study of the numerical met
Scholars have argued that the end of the Cold War and the War on Terror have radically changed the context of war and defense, diminished the role of nation-states in favor of multi-lateral defense activities, and placed a new focus on human security. International peacekeeping has superseded the traditional act of war-making as the most important defense strategy among wealthy, liberal-democratic
Telomere length is restored primarily through the action of the reverse transcriptase telomerase, which may contribute to a prolonged lifespan in some but not all species and may result in longer telomeres in one sex than the other. To what extent this is an effect of proximate mechanisms (e.g. higher stress in males, higher oestradiol/oestrogen levels in females), or is an evolved adaptation (str
The elliptic flow coefficient (v(2)) of identified particles in Pb-Pb collisions at root s(NN) = 2.76 TeV was measured with the ALICE detector at the Large Hadron Collider (LHC). The results were obtained with the Scalar Product method, a two-particle correlation technique, using a pseudo-rapidity gap of |Delta eta| > 0.9 between the identified hadron under study and the reference particles. The v
A comparative study of the central and southern parts of the Palaeoproterozoic Svecofennian orogen in the Baltic/Fennoscandian Shield and the platform area to the east and south of the Baltic Sea indicates that at least these parts of the orogen are built up of several NW-SE trending, 100-300 km wide tectonic megadomains separated from each other and complicated by major zones of mostly dextral sh
Aim: 'Being at familial risk' may have different connotations in studies on familial risk of cancer. The register-based definition of a family history considers individuals with an affected relative at familial risk independently of the family member's diagnostic time. Alternatively, the individuals are classified to be at familial risk only after the diagnosis date of their relative, relevant to
Purpose of review: We review recent evidence regarding risk factors for childhood posttraumatic stress disorder (PTSD) and treatment outcome studies from 2010 to 2012 including dissemination studies, early intervention studies and studies involving preschool children.Recent findings: Recent large-scale epidemiological surveys confirm that PTSD occurs in a minority of children and young people expo
We present preliminary evidence for a novel evolutionary hypothesis, i.e., that animals living on plants high in antimicrobial secondary metabolites could, via drift or selection, evolve weakened immune defenses and an immunological dependence on the antimicrobial properties of their plant substrate and/or the volatile mix in the air surrounding their plant. Animals experience immunological stress
In the field of developmental biology, there is compelling evidence for a network of activity of pluripotency and stem-associated genes comprising of Oct4, Nanog and nestin. During neurogenesis, the choice between enhancement versus suppression of transcriptional modulation of these identified genes determines the balance between self-renewal neural stem cells (NSC) and immature neuronal phenotype
Despite temozolomide (TMZ) treatment, the prognosis for patients with glioblastoma multiforme is still dismal. As dose escalation of TMZ is limited by systemic toxicity, intratumoral delivery emerges as an attractive treatment modality, which may sustain cytotoxic drug concentrations intratumorally and induce immunogenic cell death. Both clinical and experimental gliomas have responded to immunoth
