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Summary The CAG repeat in the androgen receptor (AR) has been widely studied in association with male infertility, but the results are conflicting. In a recent meta-analysis, infertile men had <1 repeat longer CAG stretch than fertile men when analysed in a linear regression model assuming that AR function diminishes with increasing CAG length. However, in vitro, a non-linear activity pattern was

Background Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to analyze tumor gene expression data from microarrays in the context of such pathways. Results We use pathways compiled from the TRANSPATH/TRANSFAC databases and the literature, and three publicly available cancer microarray da

The issue of word stress has not been the subject of any detailed analysis in traditional works on Romanian. It is generally assumed that stress is not predictable. The generalizations that have been made concerning stress placement are, however, made on the basis of observations of surface forms. Mallinson 1987:300 says that “stress is free and variable, giving rise to doublets: m'odele ‘the fash

Various proteases in the brain contribute to ischemic brain injury. We investigated the involvement of the asparaginyl endopeptidase legumain after experimental stroke. On the basis of gene array studies and in situ hybridizations, we observed an increase of legumain expression in the peri-infarct area of rats after transient occlusion of the middle cerebral artery (MCAO) for 120 mins with a maxim

Background and purpose There are no reports in the literature on the influence of learning on the pedicle screw insertion. We studied the effect of learning on the rate of screw misplacement in patients with adolescent idiopathic scoliosis treated with segmental pedicle screw fixation. Method We retrospectively evaluated low-dose spine computed tomography of 116 consecutive patients (aged 16 (12-2

ABSTRACT: BACKGROUND: Previous animal studies have shown that Curcuma (C.) longa lowers plasma glucose. C. longa may thus be a promising ingredient in functional foods aimed at preventing type 2 diabetes. The purpose of the study is to study the effect of C. longa on postprandial plasma glucose, insulin levels and glycemic index (GI) in healthy subjects. METHODS: Fourteen healthy subjects were ass

When skeletal muscle is stretched above optimal sarcomere length during tetanic activity there is an increase in force that stays above the isometric force level throughout the activity period. This long-lasting increase in contractile force, generally referred to as "residual force enhancement after stretch" (Fresid), has been studied in great detail in various muscle preparations over more than

In this thesis, liquid-membrane-based methods for the analysis of trace metal species in samples of environmental and biological origin were developed. By incorporating extracting reagents in the membrane liquid, trace metal ions were selectively separated from humic-rich natural waters and urine samples, prior to their determination using various instrumental techniques. The extractions were perf

As the identification process is based on the unique patterns of the users, biometrics technologies are expected to provide highly secure authentication systems. The existing systems using fingerprints or retina patterns are, however, very vulnerable. One’s fingerprints are accessible as soon as the person touches a surface, while a high resolution camera easily captures the retina pattern. Thus,

Households base their choices of heating systems on subjectively dependent conceptions of heating sources, rather than on an understanding of a complex reality. Similar to other agents in society, households need to construct simplified frames to be able to make their choices possible to manage. Using in-depth interviews with households in Småland (in Sweden) with a few comparisons from Massachuse

Popular Abstract in Swedish Fysiologisk integrering och morfologisk plasiticitet i stora klonala växter Många av våra vanligaste växter är klonala, dvs de kan producera avkommor utan sexuell befruktning. Hit räknas blåbär och lingon, många av våra vårväxter som tex. vitsippa och flera av våra värsta ogräs, som kvickrot och kirskål. En fördel som klonala växter har är att dotterskott som fortsätteClonal plants show a large variation in physiological integration, i.e. the translocation of resources among ramets within the clone. As resource transport is costly, we hypothesized that plants from poor sites should be more highly integrated than plants from rich sites and that plants would benefit if they were plastic in their degree of integration. Tracers were used to study the transport of w

The European Union’s sugar policy is one of the most distorting policies within the common agricultural policy. It includes import control, production quota, and export refunds to support producer price within the EU at levels high above international prices. The main beneficiaries of the support system are the EU sugar industries and EU beet growers, but they are not the only producers benefiting

Carotenoids are one of the most widespread and important group of pigments in Nature and they can act as light-harvesting agents, photoprotectors and antioxidants. Mechanisms of their multiple functions are not fully understood mainly because their complicated photophysics involving ?dark? excited states. The central theme of this thesis is characterization of the lowest dark S1 state of carotenoi

We have examined concurrent and prospective validity of an index of self-reported walking (RW) of 307 home-dwelling women aged 75 years and above, of whom 155 in 1 year had in all 308 falls of which 13% resulting in fractures. It consists of five items concerning various aspects of self-reported walking identified by factor analysis. The sum score on this ''RW-index'' correlated moderately ( r = 0