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Differential access to facilities for medical termination of pregnancy and delivery in India: A secondary analysis

IntroductionEmerging evidence suggests a difference in access to facilities for medical termination of pregnancy (MTP) and delivery among women in different regions of the country. However, we lack assessments at a large scale across all geographies. Our study aims to describe the percent contribution of private and public sectors in institutional deliveries and MTP in India.MethodsA secondary dat

Establishing paediatric diagnostic reference levels using reference curves - A feasibility study including conventional and CT examinations

PURPOSE: To derive Regional Diagnostic Reference Levels (RDRL) for paediatric conventional and CT examinations using weight-based DRL curves and compare the outcome with DRL derived using the weight groups.METHODS: Data from 1722 examinations performed at 29 hospitals in four countries were included. DRL was derived for four conventional x-ray (chest, abdomen, pelvis, hips/joints) and two types of

Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation

The bone morphogenetic protein (BMP) and Notch signaling pathways are crucial for cellular differentiation. In many cases, the two pathways act similarly; for example, to inhibit myogenic differentiation. It is not known whether this inhibition is caused by distinct mechanisms or by an interplay between Notch and BMP signaling. Here we demonstrate that functional Notch signaling is required for BM

Gaia Early Data Release 3 : Building the Gaia DR3 source list - Cross-match of Gaia observations

Context. The Gaia Early Data Release 3 (Gaia EDR3) contains results derived from 78 billion individual field-of-view transits of 2.5 billion sources collected by the European Space Agency's Gaia mission during its first 34 months of continuous scanning of the sky. Aims. We describe the input data, which have the form of onboard detections, and the modeling and processing that is involved in cross-

Hip dysplasia is not uncommon but frequently overlooked : a cross-sectional study based on radiographic examination of 1,870 adults

Background and purpose — Hip dysplasia in adults is a deformity in which the acetabulum inadequately covers the femoral head. The prevalence is sparingly described in the literature. We investigated the prevalence in Malmö (Sweden) and assessed whether the condition was recognized in the radiology reports. Subjects and methods — All pelvic radiographs performed in Malmö during 2007–2008 on subject

DBT-skills system for cognitively challenged individuals with self-harm: a Swedish pilot study

Background: Dialectical behavior therapy (DBT) is an evidence-based treatment for self-harm and emotion regulation difficulties. A modified version, DBT-Skills System (DBT-SS), has been developed in the USA for individuals with cognitive difficulties. The present study is a pilot study, testing the DBT-SS in a Swedish context.Methods: Six participants were treated with individual therapy and group

Cortical Activity During an Attack of Ménière's Disease-A Case Report

Background: Ménière's disease (MD) is a chronic peripheral vestibular disorder with recurrent episodes of vertigo accompanied by fluctuating hearing loss, tinnitus and aural fullness in the affected ear. There are several unanswered fundamental questions regarding MD, one of these being cortical activity during a MD attack. However, it is not possible to plan an investigation in an episodic diseas

Recent Patent based perspective on diagnostic and therapeutic interventions in Malignant Mesothelioma: Is Drug Repositioning knocking the door?

Background: Malignant Mesothelioma (MM), an orphan but aggressive malignancy of the mesothelial membrane, is a fatal tumor. Global epidemic related to malignant pleural mesothelioma is on the rise, so there is a need to explore novel biomarkers and ingenious therapeutic approaches to stalk this silent killer.Objective: The main aim of the present review is to provide a consolidated overview of the

Effects of a Four-day Spaceflight and Recombinant Human Growth Hormone on Cancellous Bone Microarchitecture in Femoral Head of Rapidly Growing Male Rats

Spaceflight results in reduced bone accrual and muscle atrophy in growing rodents. Some studies suggest that the detrimental effects of spaceflight are due, in part, to impaired growth hormone (GH) signaling. An experiment flown aboard STS-41 (October 6–10, 1990) evaluated the efficacy of recombinant human growth hormone (rhGH) in ameliorating the detrimental effects of spaceflight on the musculos

A double-edged sword : Unrecognized cryptic diversity and taxonomic impediment in Eois (Lepidoptera, Geometridae)

The genus Eois Hübner (Geometridae: Larentiinae) comprises 254 valid species. Being a hyperdiverse genus, Eois potentially includes many undescribed cryptic species and embodies a problematic taxonomic scenario. The actual diversity of Eois is greatly underestimated and the Neotropical fauna needs to be well known since it figures as one of the most threatened terrestrial ecosystem. In the present

The impact of kin proximity on net marital fertility and maternal survival in Sweden 1900-1910 – Evidence for cooperative breeding in a societal context of nuclear families, or just contextual correlations?

ObjectiveWe investigate the association between the geographic proximity of the grandparents on net marital fertility and maternal survival in Sweden, 1900–1910, within the framework of the cooperative-breeding-hypothesis.MethodsData were derived from Swedish full-count censuses (1880–1910) and the Swedish Death Index. Married couples were linked to their parental households. Poisson and logistic

Assessment of a flamelet approach to evaluating mean species mass fractions in moderately and highly turbulent premixed flames

Complex-chemistry direct numerical simulation (DNS) data obtained from lean methane-air turbulent flames are analyzed to perform a priori assessment of predictive capabilities of the flamelet approach to evaluating mean concentrations of various species in turbulent flames characterized by Karlovitz numbers K a = 6.0, 74.0, and 540. Six definitions of a combustion progress variable c are probed an

Integrating risk assessment and business impact assessment in the public crisis management sector

Risk and Vulnerability Assessments (RVAs) are often conducted by public sector organizations to prevent or prepare for hazards and threats. In Sweden, practitioners increasingly adopt approaches that are based on Business Continuity Management (BCM), where Business Impact Assessments (BIA) are used to gain organizational understanding, in favor of more traditional risk assessments. Both processes

Tenecteplase in wake-up ischemic stroke trial : Protocol for a randomized-controlled trial

Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with acu

Extensions of the SEIR model for the analysis of tailored social distancing and tracing approaches to cope with COVID-19

In the context of the COVID-19 pandemic, governments worldwide face the challenge of designing tailored measures of epidemic control to provide reliable health protection while allowing societal and economic activity. In this paper, we propose an extension of the epidemiological SEIR model to enable a detailed analysis of commonly discussed tailored measures of epidemic control—among them group-sp

From bike to electric bike level-of-service

The evaluation of electric bike (e-bike) riders’ perception of comfort can lead to a better understanding of user requirements. This can be performed through Level-of-service (LOS) studies. To date, the e-bike LOS (ELOS) concept is scarcely developed and research concerning e-bike travel behaviour characteristics is relatively sparse. In this paper, we use bike LOS (BLOS) studies as a foundation t