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AIMS: Selecting patients for cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (HIPEC) remains challenging. We compared the predictive power of three intra-operative assessment tools of peritoneal involvement of colorectal cancer.METHODS: Ninety-two procedures (1999-2005) were prospectively scored using the Simplified Peritoneal Cancer Index (SPCI) and 7 Region Count. The Perito

BACKGROUND: Peritoneal carcinomatosis in the absence of distant metastasis occurs in approximately 8 per cent of patients with colorectal cancer. Cytoreduction followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a new treatment option. Patient selection is crucial to outcome.METHODS: Cytoreduction followed by HIPEC was performed in 102 patients with peritoneal carcinomatosis. The foll

Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to contribute to high-quality personalised care at the end of life in different countries and cultures, by investigating the experiences, concerns, preferences and use of care of termin

This paper highlights changes in perceived room for agency and local institutions (formal and informal) in old Swedish mill regions. The paper draws on recent literature on change agency (Grillitsch & Sotarauta, 2020) and reproductive agency (Bækkelund, 2021; Jolly et al., 2020) as well as the role of institutions in local communities (Bole, 2021; Rodríguez-Pose, 2013) and builds on material f

Protandry is a widespread life-history phenomenon describing how males precede females at the site or state of reproduction. In migratory birds, protandry has an important influence on individual fitness, the migratory syndrome, and phenological response to climate change. Despite its significance, accurate analyses on the dynamics of protandry using data sets collected at the breeding site, are l

PURPOSE: Children with cerebral palsy (CP) are at risk of cognitive impairments and need to be cognitively assessed to allow for individualized interventions, if applicable. Therefore, a systematic protocol for the follow-up of cognition in children with CP, CP Cog, with assessments offered at five/six and 12/13 years of age, was developed. This report presents and discusses assessment practices i

Background: Sex chromosomes have evolved numerous times, as revealed by recent genomic studies. However, large gaps in our knowledge of sex chromosome diversity across the tree of life remain. Filling these gaps, through the study of novel species, is crucial for improved understanding of why and how sex chromosomes evolve. Characterization of sex chromosomes in already well-studied organisms is a

Introduction/Aim of the Study. One way of investigating health trends at the population level is to study the physical performance and functional ability in different birth cohorts. The information obtained can be used to predict illness, disability, and future needs for care. However, contradictory findings have been reported when comparing the physical performance of older adult birth cohorts. T

PURPOSE: Interventional radiology techniques cause radiation exposure both to patient and personnel. The radiation dose to the operator is usually measured with dosimeters located at specific points above or below the lead aprons. The aim of this study is to develop and validate two fast Monte Carlo (MC) codes for radiation transport in order to improve the assessment of individual doses in interv

Environmental destruction has long been used as a military strategy in times of conflict. A long-term example of environmental destruction in a conflict zone can be found in Dersim/Tunceli province, located in Eastern Turkey. In the last century, at least two military operations negatively impacted Dersim’s population and environment: 1937–38 and 1993–94. Both conflict and environmental destructio

Objectives: To investigate whether changes in complete blood count (CBC) in islet autoantibody positive children with increased genetic risk for type 1 diabetes are associated with oral glucose tolerance tests (OGTT) and HbA1c over time. Methods: The Environmental Determinants of Diabetes in the Young (TEDDY) study follows children with increased risk for type 1 diabetes in the United States, Germ

Pollinators face multiple pressures and there is evidence of populations in decline. As demand for insect-pollinated crops increases, crop production is threatened by shortfalls in pollination services. Understanding the extent of current yield deficits due to pollination and identifying opportunities to protect or improve crop yield and quality through pollination management is therefore of inter

Cities worldwide adopted lockdown policies in response to the outbreak of coronavirus disease 2019 (COVID-19), significantly influencing people's travel behavior. In particular, micro-mobility, an emerging mode of urban transport, is profoundly shaped by this crisis. However, there is limited research devoted to understanding the rapidly evolving trip patterns of micro-mobility in response to COVI

ObjectiveThis article explores whether there is a systematic variation in conventional and unconventional political participation as a function of in-group versus out-group trust. We postulate that the narrower the moral community is, the more political participation is restricted to conventional activity that is perceived as an obligation, as a political act to be fulfilled, something akin to cit

The C-terminal-fragments of alpha1-antitrypsin (AAT) have been identified and their diverse biological roles have been reported in vitro and in vivo. These findings prompted us to develop a monoclonal antibody that specifically recognizes C-36 peptide (corresponding to residues 359–394) resulting from the protease-associated cleavage of AAT. The C-36-targeting mouse mono-clonal Immunoglobulin M (I