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Popular Abstract in Swedish Dermatansulfat liksom kondroitinsulfat är ogrenade kolhydratkedjor som består av aminosockret N-acetylgalaktosamin samt uronsyrorna (sockersyrorna), glukuronsyra eller iduronsyra i repeterande enheter om par två och två. Dessa kedjor, som dessutom är bundna med en esterbindning till aminosyran serin på en proteinstam, kan bestå av nästan ett par hundra modifierade sockeDermatan sulphate is a prominent feature of several different proteoglycans and occurs in almost every tissue of the body. It is an unbranched polymer containing the repeating disaccharide unit of N-acetylgalactosamine and D-glucuronic acid or L-iduronic acid. The polymer can be highly sulphated resulting in an unusual and largely unknown diversity in the chain. The unique step in dermatan sulphat

This thesis addresses powder manufactured (P/M) components, with special attention to the compaction process and to the sensitivity to damage accumulation due to fatigue within powder compacted specimens. Three dimensional simulations of the compaction process have been performed, using an explicit dynamic dilatant finite strain finite element code supplemented with the effects from contact fricti

Hematopoietic stem cells are an ideal target for genetic manipulation for the purpose of curing hematological disorders as they have the ability to develop into all blood lineages and to self-renew. In this study we demonstrate that lentiviral vectors, based on HIV-1, can efficiently transfer genes into human hematopoietic progenitor and stem cells as assessed following stem cell transplantation i

Saccharomyces cerevisiae produces ethanol efficiently from the hexose sugars in lignocellulose hydrolysates, but it can not utilise pentose sugars such as xylose and arabinose. Stable xylose-utilising S. cerevisiae strains obtained by integration of the Pichia stipitis genes encoding xylose reductase (XR), xylitol dehydrogenase (XDH) and xylulokinase, exhibit low ethanol yields when utilising xylo

Popular Abstract in Swedish Med dagens alla transporter finns det ett mycket stort behov av tillgång till billigt och miljövänligt drivmedel. Det bränsle som används i särklass mest är bensin framställd från råolja. Ett problem med bensinen är att den inte tillverkas från förnyelsebara råvarukällor. Detta innebär att när oljan tar slut så går det inte att tillverka mer bensin. Däremot är det idag

Popular Abstract in Swedish I vårt vardagliga liv träffar vi på en mängd apparater som använder sig av överföring och lagring av information. Ett par exempel på sådana är CD-spelare, mobiltelefoner och datorer. I de flesta av alla dessa apparater lagras eller överförs informationen på digital form, det vill säga man använder sig av ett ändligt antal symboler för att representera informationen. EttThis thesis focuses on different convolutional coding constructions for digital communication systems, and on methods to analyze these constructions. The work presented in the thesis can be divided into three main areas; error probability bounds for convolutional codes, analysis of multilevel modulation, and investigation of low-density parity-check convolutional codes. New bounds are developed f

Objectives. To compare perinatal and infant mortality in breech and cephalic presentations and between planned vaginal and cesarean section (CS) breech deliveries in Sweden. Methods. The study comprised two parts. Study A is a national cohort study for the period 1991-2001, including 22 549 breech presentations and 875 249 cephalic presentations born at >= 38 completed weeks. Study B is a case-con

The sympathetic nervous system has been shown to exert a trophic influence on vascular smooth muscle cells (VSMC). Therefore, we studied the growth-regulating effects of the sympathetic cotransmitters ATP, neuropeptide Y (NPY), and norepinephrine (NE). ATP in concentrations of 1-100 microM greatly increased the incorporation of [3H]thymidine in VSMC from rat aorta and vena cava. ATP also increased

Background. In some western populations, increased serum uric acid has been positively associated with cardiovascular disease, possibly because hyperuricaemia could be an untoward part of the insulin-resistant metabolic syndrome. However, there is evidence that uric acid is a free radical scavenger capable of inhibiting LDL oxidation. Amongst the traditional horticulturalists of Kitava, Trobriand

Objective: Interstitial laser coagulation (ILC) of the prostate is a minimally invasive method for treating symptomatic benign prostatic enlargement (BPE). We performed a prospective randomized study to compare the clinical outcomes of ILC and transurethral resection of the prostate (TURP). Material and Methods: Between December 1997 and February 2000, 38 patients with moderate-to-severe symptomat

Patients attending the emergency room with acute asthma, participating in a study comparing salbutamol (albuterol in the United States) via a dry powder inhaler (Turbuhaler) with pressurized metered-dose inhaler (pMDI), were included in this 1-week follow-up study with the aim of assessing whether inhaled budesonide via Turbuhaler may be an alternative to prednisolone tablets after an acute asthma

Gliomas are among the most aggressive malignant tumors and the most refractory to therapy, in part due to the propensity for malignant cells to disseminate diffusely throughout the brain. Here, we have used 27 K cDNA microarrays to investigate global gene expression changes between normal brain and high-grade glioma (glioblastoma multiforme) to try and better understand gliomagenesis and to identi

Chagasin is a protein produced by Trypanosoma cruzi, the parasite that causes Chagas' disease. This small protein belongs to a recently defined family of cysteine protease inhibitors. Although resembling well-known inhibitors like the cystatins in size (110 amino acid residues) and function (they all inhibit papain-like (Cl family) proteases), it has a unique amino acid sequence and structure. We

Popular Abstract in Swedish Avhandlingen behandlar reglertekniska problem orsakade av friktion. Tre aspekter behandlas: modellering, analys av självsvängningar orsakade av friktion och friktionskompensering. En ny relativt enkel matematisk modell för friktion presenteras och studeras. Modellen kan återge experimentella observationer av friktionsbeteende. Matematiska verktyg för att bestämma självs

The value of bone mineral density (BMD) measurements to stratify fracture probability can be enhanced in a case-finding strategy that combines BMD measurement with independent clinical risk indicators. Putative risk indicators include age and gender, BMI or weight, prior fracture, the use of corticosteroids, and possibly others. The aim of the present study was to develop a mathematical framework

Fifteen years after the heavy storm "Vivian", it is still not clear how succession in subalpine forests that were affected by the storm will continue and when regrowing forests will provide effective protection from natural hazards such as avalanches. We used a simulation model to evaluate forest succession, forest structure and the protective effect in subalpine blowdown areas after 50 simulation

The human platelet cilostamide- and cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) was rapidly purified approximately 19,000-fold to apparent homogeneity using single step affinity chromatography on the isothiocyanate derivative of cilostamide coupled to aminoethyl agarose. Within 24 h, 30 micrograms of enzyme protein was obtained from 20 ml of packed platelets. Vmax for cAMP and cGMP was 6.1 and