Filtyp
Previous studies have suggested that the frequency of chromosomal aberrations (CAs), but not of sister chromatid exchanges (SCEs), predicts cancer risk. We have further examined this relationship in European cohorts comprising altogether almost 22,000 subjects, in the framework of a European collaborative project (CancerRiskBiomarkers). The present paper gives an overview of some of the results of
Popular Abstract in Swedish Populärvetenskaplig sammanfattning Introduktion Adrenokortikotropiskt hormon (ACTH) stimulerar frisättningen av steroid¬hormoner, främst kortisol, från binjurarna. Kortisol är livsnödvändigt och finns alltid i blodet och förhöjs kraftigt vid stress. I början av 90-talet fann vår forskningsgrupp en koppling mellan ACTH och fettomsättningen som inte involverade steroidhAbstract Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. In contrast, levels of HDL increase about 10%. In hepatic cell cultures, ACTH inhibits expression and secretion of apoB. In this thesis we corroborate that the reduced apoB synthesis, seen in hepatic cell systems, is als
Background. Previous studies have demonstrated that anti-CD40L or anti-B7 requires the presence of CD4(+)CD25(+) regulatory T cells (Treg) to induce antigen specific hyporesponsiveness. Other tolerance strategies involving Treg have shown a dependency on interleukin (IL)-10. The objective of this study was to investigate the role of CD4(+)CD25(+) Treg and IL-10 when treating transplant recipients
alpha-Cells were identified in preparations of dispersed mouse islets by immunofluorescence microscopy. A high fraction of alpha-cells correlated with a small cell size measured as the average cell diameter (10 microm) and whole-cell capacitance (<4 pF). The alpha-cells generated action potentials at a low frequency (1 Hz) in the absence of glucose. These action potentials were reversibly inhibite
Popular Abstract in Swedish Under det senaste decenniet har föräldrars intresse att välja fristående skolor för sina barn ökat markant. Läsåret 1998-99 gick, enligt Skolverket (1999), drygt 30 000 eller 3 % av grundskolans elever i fristående skolor. Det är emellertid en stor variation mellan landets kommuner. Trots den ringa andel som eleverna i fristående skolor utgör, har diskussionen om skolor
This study examines processes of transnational alliance-building among political parties in the European Union (EU). It is associated with theories of transnational relations, neofunctionalist integration theory and domestic politics approaches to international co-operation and integration. The overall aim of the study is to contribute to the understanding and growth of knowledge of transnational
Background: Reduced quadriceps strength is an early finding in subjects with knee osteoarthritis, but it is not clear whether it is a cause or a consequence of knee osteoarthritis. Objective: To determine whether reduced functional performance in the lower extremity predicts the incidence or progression of radiographic knee osteoarthritis. Design: Prospective, epidemiological, population based c
The first aim of this doctoral work has been to develop a new generation of computer programs for transient and steady-state heat conduction in two and three dimensions. A large range of heat transfer problems within the field of buildings physics can be analyzed using these tools. There are, however, many things to keep in mind when modelling a problem, such as how to choose the numerical mesh,
OBJECTIVE: To explore the utility of cluster analysis in defining complex dietary exposures, separately with two types of variables. DESIGN:: A modified diet history method, combining a 7-day menu book and a 168-item questionnaire, assessed dietary habits. A standardized questionnaire collected information on sociodemographics, lifestyle and health history. Anthropometric information was obtained
Background and Objectives: Intense pulsed light (IPL) systems are increasingly used for treatment of photo damaged skin. In the present study, we investigated the clinical efficacy and safety of two different wavelength bands generated by the same IPL device. Study Design/Materials and Methods: An IPL device was equipped with either a 555-950 nm filter (VL), or a 530-750 nm filter (PR). Results: F
Nutrient availability is a major constraint to plant production and carbon storage in arctic ecosystems, but there are few studies coupling processes in the decomposer and microbial food web and the implications these processes have on the control of nutrient mineralization. We studied the relationship between microbial biomass and the abundance of microbivore and the role of grazing on nutrient t
Det primära syftet med studien var att undersöka genomförbarheten av dagliga skattningar två gånger dagligen av symtom, psykologisk flexibilitet (PF) och funktion hos vuxna med systemisk lupus erythematosus (SLE). Det sekundära syftet var att undersöka sambandet mellan de vanligaste och mest besvärande symtomen på SLE (dvs. smärta, trötthet, ångest, depression och kognitiv påverkan), hälsorelateraThe primary aim of this study was to assess the feasibility of obtaining twice-daily recordings of symptoms, psychological flexibility (PF) and functioning from adults with Systemic Lupus Erythematosus (SLE). The secondary aim was to investigate the relationship between the most common and burdensome symptoms of SLE (i.e., pain, fatigue, anxiety, depression and cognitive impairment – CI), health r
Vid 1900-talets början så såg världskartan mycket annorlunda ut jämfört med idag. Stora delar av världens befolkning stod under ett främmande, ofta europeiskt, styre och saknade inom ramen för detta system en möjlighet att påverka sin regim. Detta förändrades drastiskt under andra halvan av 1900-talet där nya organisationer, som Förenta nationerna, fick allt större inflytande och spelrum. Detta leDuring the 20th century the world changed drastically. In the first half of the century, large areas of the world were under, usually, European rule and the people living there lacked the ability to govern themselves. This changed radically under the second half and with new organizations, such as the United Nations, the global campaign for decolonization started. This was done under the banner of
Psykiskt våld är i viss utsträckning kriminaliserat genom befintliga straffbud. Utredningar påvisar dock att dessa straffbud sällan tillämpas på psykiskt våld trots att bestämmelsernas ordalydelse tillåter det. Psykiskt våld har därför varit föremål för åtskilliga lagstiftningsprojekt genom åren. Att kriminalisera psykiskt våld särskilt har emellertid aldrig ansetts möjligt enligt de lydelser som Psychological violence is to some extent criminalized by existing penal provisions. Nonetheless, studies show that these provisions are rarely applied to psychological violence, even though the wording of the provisions allows it. Psychological violence has therefore been the subject of several legislative projects over the years. However, specifically criminalizing psychological violence has neve
Abstrakt Bakgrund: Allt flera människor flyr från sitt hemland pga. krig, hot eller förföljelse, de söker skydd hos mottagande land. Papperslösa personer tillhör dessa grupp av människor, de är en extremt utsatt grupp bland Europas befolkning både inom vården och bland allmänheten. De får oftast ojämlikt vård och riskerar därför att få sämre hälsoutfall jämfört med resten av befolkning. Majoritete
The last mass-extinction event happened over 65 million years ago when an asteroid collided with earth, resulting in the loss of 76% of all species. Scientists now warn that we are on the precipice of a new mass-extinction, the responsibility of which can be placed entirely on one species, the homo sapiens. While some species of birds, bats, and arthropods are especially vulnerable, we are all int
Öresundsområdet har en unik ställning i Sverige genom att ha en tät förbindelse till Danmarks huvudstad och kommersiella centrum. För att stärka möjligheten att nyttja denna täta förbindelse ingicks 2003 det så kallade Öresundsavtalet. Öresundsavtalet behandlar i huvudsak beskattning av personer som bor på den ena sidan av Öresund och arbetar på den andra och möjliggör således i större utsträckninThe Öresund region has a unique position in Sweden in that it is closely linked to the Danish capital and commercial centre. In order to strengthen the possibility of utilising this close connection, the so-called Öresund Agreement was concluded in 2003. The Öresund Agreement deals mainly with taxation of persons living on one side of the Öresund and working on the other, and thus enables more str
Modern video streaming may use the protocol H.264 to encode video in high quality. The protocol takes advantage of similarities between consecutive frames to lower the bit rate. If there are differences between frames the bit rate will therefore rise. To control the fluctuations in bit rate a rate controller (RC) can be used together with the encoder. The RC manages the quantisation levels of the
