Filtyp
Objective: To determine the incidence and clinical significance of neutralizing antibody (NAb) formation in patients with relapsing multiple sclerosis ( MS) who participated in the European Interferon Beta-1a IM Dose-Comparison Study. Methods. Patients were randomized to treatment with interferon beta-1a (IFN beta-1a) 30 mu g or 60 mu g IM once weekly for up to 4 years. Serum samples obtained at b
Background: The clinical benefit of combining long-acting beta(2)-agonists with inhaled corticosteroids rather than doubling the dose of corticosteroid has been well-documented. However, there are concerns that this might result in a masking of underlying airway inflammation. Objective: The aim of this study was to test the hypothesis that the addition of the long-acting beta(2)-agonist salmeterol
Popular Abstract in Swedish Chefskap och ledarskap hos sjuksköterskor i högre chefsbefattningar inom hälso- och sjukvården. I dagens hälso- och sjukvård har sjuksköterskor i chefsposition en förändrad och utökad roll, bland annat till följd av decentraliserade organisationer och utökade ansvarsområden. Utvecklingen av omvårdnaden kommer till en del att vara beroende av chefernas förmåga och skickThe aim of this thesis was to illuminate the management and leadership of nurse managers within Swedish health care organizations and to recognize influencing factors of importance for the nurse managers in exercising and developing their management. The interviewees were all active in their positions at the time of the interviews. The nurse managers served at top management levels in either execu
Popular Abstract in Swedish De vardagliga ting som omger oss, allt från leksaker till bilar, såväl som den utrustning som används i tillverkningen av dem innehåller ett växande antal inbyggda datorer. Inbyggda system är ofta ansvariga för kritisk funktionalitet, vilket leder till att en mängd tids- och resurskrav måste uppfyllas. Industriell konkurrens och det ständigt växande förhållandet mellan
We report on a dedicated effort to identify and study metal-poor stars strongly enhanced in r-process elements ([r/Fe]>1 dex; hereafter r-IIstars), the Hamburg/ESO R-process Enhanced Star survey (HERES).Moderate-resolution (∼2 Å) follow-up spectroscopy has been obtained for metal-poor giant candidates selected from the Hamburg/ESO objective-prism survey (HES) as well as the HK survey to identify s
Popular Abstract in Swedish I ett ökande antal regioner i världen finns det arbetande barn som organiserar sig utifrån sin identitet som arbetande barn. Jag har studerat tre olika unioner i delstaten Karnataka i Indien, där jag har fokuserat på hur dom själva upplever mobiliseringen och vilka möjligheter de har att förändra sin situation inom existerande normer, traditioner och samhällsstrukturer.
Conservation and land management decisions may be misguided by inaccurate or misinterpreted knowledge of biodiversity. Non-systematists often lack taxonomic expertise necessary for an accurate assessment of biodiversity. Additionally, there are far too few taxonomists to contribute significantly to the task of identifying species for specimens collected in biodiversity studies. While species level
Rainflow cycles are often used in fatigue analysis of materials for describing the variability of applied loads. Therefore, an important characteristic of a random load process is the intensity of rainflow cycles, also called the expected rainflow matrix (RFM), which can be used for evaluation of the fatigue life. In this thesis mainly two problems are addressed: the first is computation of the ex
Background: Within 5 years following radical prostatectomy, between 15 and 60% of patients with pT3 prostate carcinomas show an increasing prostate-specific antigen (PSA) as a sign of local and/or systemic tumour progression. Adjuvant radiotherapy (RT) for positive margins (RI) aims to reduce residual tumour cells in the prostatic bed, thus possibly reducing the biochemical progression rate. Apart
OBJECTIVES: To test prospectively the diagnostic performance of two logistic regression models for calculation of individual risk of malignancy in adnexal tumors (the 'Tailor model' and the 'Timmerman model'), and to compare them to that of 'pattern recognition' (subjective evaluation of the gray-scale ultrasound image and color Doppler ultrasound examination). DESIGN: Consecutive women with a pel
Soot particle (black carbon) morphology is of dual interest, both from a health perspective and due to the influence of soot on the global climate. In this study, the mass-mobility relationships, and thus effective densities, of soot agglomerates from three types of soot emitting sources were determined in situ by combining a differential mobility analyzer (DMA) and an aerosol particle mass analyz
A new, two-layer canopy module with thermal inertia as part of the detailed snow model SNOWPACK (version 3.2.1) is presented and evaluated. As a by-product of these new developments, an exhaustive description of the canopy module of the SNOWPACK model is provided, thereby filling a gap in the existing literature. In its current form, the two-layer canopy module is suited for evergreen needleleaf f
Optimizing cheese yield and quality is of central importance to cheese manufacturing. The yield is associated with the time it takes before the gel has an optimal consistency for further processing, and it is well known that gel formation differs between individual milk samples. By identifying genomic regions affecting traits related to rennet-induced gelation, the aim of this study was to identif
The European electric power industry has undergone considerable changes over the past two decades as a result of more stringent laws concerning environmental protection along with the deregulation and liberalization of the electric power market. However, the pressure to deliver solutions in regard to the issue of climate change has increased dramatically in the last few years and has given rise to
Levodopa is the mainstay of Parkinson''s disease (PD) treatment, but is often eventually associated with disabling motor complications in patients with advanced PD. The inability of perorally administered levodopa to provide more physiologic continuous dopaminergic stimulation (CDS) is a leading hypothesis to explain these complications. To investigate the cumulative efficacy and safety, and re-ev
P>Background: PET using 1-11C-acetate (ACE-PET) applied at rest is used for measuring absolute myocardial blood flow (MBF) and oxidative metabolic rate (k(mono)). We evaluated the feasibility of quantitative ACE-PET during exercise. Methods: Five endurance athletes underwent dynamic PET scanning at rest and during supine bicycle stress. Exercise was maintained at a workload of 120 Watt for 17 min.
BACKGROUND The association between aging-related testosterone deficiency and late-onset hypogonadism in men remains a controversial concept. We sought evidence-based criteria for identifying late-onset hypogonadism in the general population on the basis of an association between symptoms and a low testosterone level. METHODS We surveyed a random population sample of 3369 men between the ages of 40
