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Introduction The LINC trial evaluated two ALS-CPR algorithms for OHCA patients, consisting of 3 min’ mechanical chest compression (LUCAS) cycles with defibrillation attempt through compressions vs. 2 min’ manual compressions with compression pause for defibrillation. The PARAMEDIC trial, using 2 min’ algorithm found worse outcome for patients with initial VF/VT in the LUCAS group and they received
The demographic changes in society with growing numbers of elderly subjects will inevitably increase admission rates to acute emergency departments (AMU). Early discharge might augment emergency readmissions due to a relapse in medical conditions. Our aim was to study precipitating factors in frail elderly patients who got the diagnosis 'lack of community support' after initial medical examination
Background: The goals of palliative care are to relieve suffering and promote quality of life. Palliative care for older persons has been less prioritised than palliative care for younger people with cancer, which may lead to unnecessary suffering and decreased quality of life at the final stage of life.Aim: To evaluate whether a palliative care intervention had any influence on the perceived qual
PURPOSE: Hypoxia is one of the most important factors influencing clinical outcome after radiotherapy. Improved knowledge of factors affecting the levels and distribution of oxygen within a tumor is needed. The authors constructed a theoretical 3D model based on histological images to analyze the influence of vessel density and hemoglobin (Hb) concentration on the response to irradiation.METHODS:
Understanding the relationships between biodiversity and land-use is a key element for the development of effective conservation strategies. We studied a mid-altitude steppe-like area of Southern France, the Causse de Sauveterre, that has been grazed for many centuries. The decrease of human population during the 20th century, particularly since the end of 2nd World War, and the ongoing changes in
Europe is one of the world's largest food producers, and climate change may pose a serious threat to food security in the region. In the present study, we assess the potential impact of climate change on the Colorado Potato Beetle (CPB), Leptinotarsa decemlineata (Say)-a severe pest of potato (Solanum tuberosum, L.). We also investigate the possible impact of climate change on the phenological dev
Background: Systemic Sclerosis (SSc) is an autoimmune disease characterized by vascular and immune dysfunction. A hallmark of SSc is the excessive accumulation of extracellular matrix in the skin and in internal organs. There is a high and unmet medical need for novel therapies in this disease. The pathogenesis of SSc is complex and still poorly understood, but the innate immune system has emerged
Inom fysik försöker vi beskriva naturfenomen med matematiska modeller. Beroende på vilket system som ska beskrivas är olika modeller relevanta. På väldigt långa avstånd är gravitation den viktigaste kraften. Till exempel så beskrivs solsystemets dynamik av gravitation. På de kortaste avstånd som människan lyckats studera är det istället den elektromagnetiska, den svaga och den starka kraften som äIn this thesis we use effective field thory methods and models for low energy QCD in two different contexts. One is direct calculation of contributions to the anomalous magnetic moment of the muon, muon g-2. The other is estimates of systematic sources of uncertainty in lattice QCD simulations. The work is presented in five papers. Papers II, IV and V describe calculations for muon g-2 and papers
Background: In 2014 the Swedish government assigned to The Public Health Agency of Sweden to conduct studies to evaluate optimal use of existing antibiotic agents. The aim is to optimize drug use and dosing regimens to improve the clinical efficacy. The present study was selected following a structured prioritizing process by independent experts. Methods: This phase IV study is a randomized, open-
A new, integrated, diagnosis tool in the field of industrial sustainability management named the ‘Initial Review for Sustainable Consumption and Production.’ was developed and tested. Most of the existing tools for an initial diagnosis and for identification of suitable interventions in this area have some of the following drawbacks: a. they are incomplete because they do not address all levels of
För att skapa matematiska beskrivningar av fysiska fenomen inom bland annat naturvetenskap, teknik och medicin används ofta partiella differentialekvationer. Listan med tillämpningar kan göras hur lång som helst: sådana ekvationer kan beskriva hur en snöflinga bildas, hur strukturer deformeras när de utsätts för mekaniska krafter, hur partiklar interagerar på kvantnivå, hur blodet flödar i hjärnanSplitting methods are widely used temporal approximation schemes for parabolic partial differential equations (PDEs). These schemes may be very efficient when a problem can be naturally decomposed into multiple parts. In this thesis, splitting methods are analysed when applied to spatial splittings (partitions of the computational domain) and physical splittings (separations of physical processes)
Mobility-as-a-Service (MaaS) has been argued as part of the solution to prevalent transport problems. However, progress from pilots to large-scale implementation has hitherto been slow. The aim of the research reported in this paper was to empirically and in-depth investigate how, and to what extent, different factors affect the development and implementation of MaaS. A framework was developed, wi
BACKGROUND: Overweight and gestational diabetes are risk factors for pregnancy complications. We hypothesized that the metabolic impact of overweight on pregnancy outcome, would be different if it was combined with a predisposition for diabetes. The aim of this study was to compare the outcome of pregnancies in women with diabetes diagnosed later in life, to the outcome of pregnancies of women who
A growing body of literature on the 2019 novel coronavirus (SARS-CoV-2) is becoming available, but a synthesis of available data has not been conducted. We performed a scoping review of currently available clinical, epidemiological, laboratory, and chest imaging data related to the SARS-CoV-2 infection. We searched MEDLINE, Cochrane CENTRAL, EMBASE, Scopus and LILACS from 01 January 2019 to 24 Feb
Populärvetenskaplig sammanfattningEn stor del av världens energikällor är baserade på förbränning och kan återfinnas i allt från bilar och båtar som drivs av förbränningsmotorer till gasturbiner och kraftverk som används till elproduktion. Den centrala biten inom förbränning är en kemisk omvandling av bränslet då det reagerar med syre till att bilda de två huvudsakliga produkterna, vatten och koldAbstractThe work presented in this thesis is mainly focused on the development andapplication of infrared laser-induced grating techniques in order to measure the gasphase temperature and species concentrations in reactive flows. The two techniquesused for this purpose are laser-induced grating spectroscopy (LIGS) and degeneratefour-wave mixing (DFWM). Their coherent nature allows to perform laser
