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Vigabatrin is an antiepileptic drug that is known to cause visual field defects and retinal dysfunction measured by full-field electroretinography (ff-ERG). Underlying mechanisms have not yet been elucidated. The aims of this thesis were to investigate parameters of vigabatrin treatment; reversibility of visual dysfunction, prevalence of retinal dysfunction in children, role of drug-dose and evalu
Background: Growing worldwide evidence shows that the experience of sexual coercion is fairly prevalent among young people and is associated with risky sexual behavior thereafter. The causal mechanisms behind this are unclear but may be dependent on specific contextual determinants. Little is known about factors that could buffer the negative effects of coercion. The aim of this study was to asses
Background: Severe traumatic knee injury, including injury to the anterior cruciate ligament (ACL), leads to impaired sensorimotor function. Although improvements are achieved by training, impairment often persists. Because good sensorimotor function is associated with better patient-reported function and a potential lower risk of future joint problems, more effective treatment is warranted. Tempo
Life-history theory concerns the trade-offs that mold the patterns of investment by animals between reproduction, growth, and survival. It is widely recognized that physiology plays a role in the mediation of life-history trade-offs, but the details remain obscure. As life-history theory concerns aspects of investment in the soma that influence survival, understanding the physiological basis of li
Objectives: Cadmium (Cd) toxicity of the kidney varies between individuals despite similar exposure levels. In humans Cd is mainly bound to metallothioneins (MT), which scavenge its toxic effects. Here we analyzed whether polymorphisms in MT genes MTIA and MT2A influence Cd-related kidney damage. Methods: In a cross-sectional study N = 512 volunteers were selected from three areas in South-Eastern
Study I: Thirteen patients underwent a modified Ross operation in which the free-standing pulmonary autograft was supported externally by a Dacron vascular prosthetic jacket (DVPJ). The tailor-made DVPJ prevented dilatation of the neo-aortic root significantly following a median follow-up of 47 months compared to a cohort of l3 matched patients undergoing conventional Ross operation. Study II: A
The increasing demand for solid biofuels, such as logging residue fuels, has highlighted the importance of considering that, in contrast to fossil fuels, biofuels are produced in dynamic ecosystems. The environmental effects of changes in management policy, whether positive and negative, are not obvious. For example, calculations of the carbon budget in single forest stands show that the carbon ba
Some markets represent companies that offer similar products in terms of design, quality and price. In this reality competitive advantages have to be created and developed in other ways. Many companies have therefore chosen a market oriented strategy that focuses on the client and their needs. According to studies within the field of Service management the interaction between the company and the c
Title: Brain Gym®? An approach to increase self-knowledge in situations of learning?- A study at the Malmö Academy of Music from a teacher and student perspective. Brain Gym® is a method developed by Paul Dennison in his studies of physiology and aims to eliminate potential blockages during the process of learning. During the influence of stress, as in learning, we do not possess a total access to
Allt fler kommuner utformar och använder digitala tvillingar eller 3D stadsmodeller för att tillgodose sina behov inom bl.a. stadsplanering och bygglov. Inom byggbranschen så ökar användningen av byggnadsinformationsmodellering (BIM) i framförallt planering- och projekteringsstadiet. Frågan är hur man kan utbyta denna digitala information från respektive bransch i bygglovsprövningar. I nuläget så
Geospatial data analysis plays a critical role in a wide range of applications, from urban planning and environmental monitoring to disaster response and infrastructure management. However, it remains technically demanding and largely inaccessible to non-experts due to the complexity of geospatial data structures, domain-specific tools, and the need for advanced programming knowledge. A particular
This paper aims to examine women as formal leaders in social work, focusing on their own experiences, perceptions, and management of expectations regarding leadership and how expectations affect the practice of their leadership. This paper is based on a gender perspective where the focus is on examining the importance of gender and gender in relation to, among other things, expectations and ideals
Context. The adverse effects of interstellar extinction makes the optical range unsuitable for spectroscopic analysis of stellar populations in dust-obscured regions of the Milky Way. With new instruments available, high-quality spectroscopy in the near-infrared (near-IR or NIR) range is now feasible. However, this region of the electromagnetic spectrum is relatively unexplored for the purpose of
Dead wood is a key element in forest ecosystems and a wide range of organisms are dependent on this substrate for development and reproduction. Saproxylic beetles are important decomposers of dead wood and serve as food for many organisms. Due to the significant forestry-related decrease of dead wood in rural areas, many species of saproxylic beetles are considered threatened. Thus, other spaces h
I Sverige idag finns det ett ökande antal barn som begår brott i kriminella nätverk. Den organiserade brottsligheten i stort pekas av flera aktörer ut som samhällsfarlig, särskilt av den sittande regeringen. Som del av den nationella strategin att slå tillbaka mot den organiserade brottsligheten gav regeringen en särskild utredare i uppdrag att utreda ett antal stora ändringar på straffrättens omr
Abstract - Instructional Course Structure • Chair: Jenny Carroll. • Speakers: Lisbeth Nilsson, Kirsty Taylor and Iwona Orlowska. Objectives • To share the process and outcomes of establishing an early mobility playgroup for children aged 6 months - 3 years who have complex neuro-disability. • To explore how the ‘Driving to Learn’ approach and the ALP-tool (Assessment of Learning Powered mobility
Our conceptual understanding is a dual one, where opposing pairs define our world. This dualistic system is sexualised, hierarchical and normative when it comes to gender perceptions. In the liberal tradition of ideas, the meaning of Equality can be deduced from the concept developed by Aristotle: treat like cases as like, and treat different cases differently. During more than three decades, the
Syftet med denna uppsats är att utreda hur försäkringstagaren, vid skada på byggnad, ska ersättas ur företagsförsäkringen respektive konsumentförsäkringen. När skada uppkommer på byggnad tillämpas värderingsreglerna i kapitel 6 i FAL för att bestämma storleken på försäkringsersättningen. Den metod som stadgas i FAL är dagsvärdemetoden. Ersättning enligt dagsvärdet anses motsvara återanskaffningsThe purpose of this thesis is to analyse how the insured shall be compensated by the insurance companies, in regards to damages to buildings. When a building is damaged the rules of valuation, found in chapter 6 of FAL (the Swedish Insurance Act), will be applied to determine the amount of the reimbursement. The method that is provided in FAL is the current value method. Compensation according t
