Sökresultat

Popular Abstract in Swedish Diabetes mellitus är en samling sjukdomar som karaktäriseras av förhöjt blodsocker. Traditionellt har man delat upp sjukdomen i två former; typ 1 och typ 2 diabetes. Vid typ 1 diabetes förstörs de insulinproducerande β-cellerna i bukspottskörteln av kroppens immunförsvar och sjukdomen debuterar ofta tidigt i livet. Typ 2 diabetes, tidigare ofta benämnd ”åldersdiabetes” Inadequate insulin secretion is a central component in the development of Diabetes Mellitus, resulting from reduced pancreatic β-cell mass, as well as diminished β-cell function. Islet produced 5-hydroxy tryptamine (5-HT) is suggested to regulate insulin secretion and β-cell mass in rodents during pregnancy and in metabolically challenged states. However, the role of 5-HT in control of insulin rel

Popular Abstract in Swedish Adenovirus från människa (Ad) används ofta vid genterapi mot cancer, vaccinutveckling och genöverföring. Modifierade Ad5 och Ad2 virus har framgångsrikt använts som cancercelldödande (onkolytiska) agens i experimentella studier som dock inte kunnat överföras till kliniskt bruk av flera skäl, inklusive bristande spridning av virusinfektionen inom tumörvävnaden. De onkoly

Background Hazardous drinking has been associated with an increased postoperative complication rate after surgery. Common complications include postoperative infections, cardiopulmonary complications, and bleeding episodes. Preoperative abstinence may to some degree reverse alcohol-induced pathophysiological processes and thus prevent postoperative complications. Objectives To assess the effect of

AIMS/HYPOTHESIS: Substantial deposition of the extracellular matrix component hyaluronan (HA) is characteristic of insulitis in overt type 1 diabetes. We investigated whether HA accumulation is detectable in islets early in disease pathogenesis and how this affects the development of insulitis and beta cell mass.METHODS: Pancreas tissue from 15 non-diabetic organ donors who were positive for islet

Sin ringa storlek till trots har insekter enorm inverkan på vårt samhälle och våra liv. Bin, som är centrala för att vårt jordbruk ska fungera, har minskat drastiskt i antal de senaste åren. En utbredd bidöd skulle i bästa fall tvinga oss lägga om vår kosthållning markant, och i värsta fall leda till svält. Utöver detta skulle växter som är beroende av bin för sin fortplantning och djur som äter bThis thesis treats entomological lidar from various angles: laboratory reference work on insects of interest, methodological development of lidar- and data processing methods, as well as field implementations of lidar techniques for entomological research. Insects are crucial components of ecosystems and are currently in a global decline. In this thesis, insects are mainly studied in their roles a

BACKGROUND: Transient tachypnoea of the newborn (TTN) is characterized by tachypnoea and signs of respiratory distress. Transient tachypnoea typically appears within the first two hours of life in term and late preterm newborns. The administration of corticosteroids might compensate for the impaired hormonal changes which occur when infants are delivered late preterm, or at term but before the ons

Background/Purpose: The aim of this study was to estimate the incidence rate and prevalence of coronary artery diseases (CAD) in patients with temporal artery positive giant cell arteritis (TAB+GCA) from a defined population in southern Sweden, and to describe characteristics of CAD in this sample.Methods: The study cohort consisted of 1202 patients (71.9% women) diagnosed with TAB+GCA between 199

I takt med att befolkningen i Sverige har ökat har även behovet av mat blivit större. För att producera mer mat har jordbruket intensifierats och användandet av gödsel och bekämpningsmedel har ökat. Förutom de positiva effekterna med högre skördar har detta även skapat miljöproblem. Ett av dessa är övergödning, som på sommaren orsakar den algblomning man kan se i sjöar och hav. Ett annat problem äThe Swedish agriculture has become more intense and large-scale by the use of artificial fertilizers and chemical pesticides. While the intensification has contributed to an increased harvest, it has also brought with it several environmental problems. This thesis brings up two of the main problems: eutrophication and the loss of biodiversity. These problem areas are also addressed by the Swedish

Kreditsäkerheter i fartyg kan upplåtas genom ett flertal olika konstruktioner. Denna uppsats avhandlar tre utav dessa varianter; sjöpanträtt i fartyg, retentionsrätt och ägarförbehåll till helt fartyg. Sjöpanträtt i fartyg är en legal panträtt som i princip inte kan upplåtas genom avtal. Sjöpanträtt uppkommer som en giltig sakrätt endast för sådan skada som har ett direkt samband med fartygets veCredit securities in ships can be provided for by several different constructions. This thesis focuses on three of these varieties; maritime liens in ships, right to retention and title reservations in ships. Maritime liens in ships is a legally granted right that principally cannot be obtained by contractual agreements. Maritime liens evolve as a valid right in rem only for such situations speci

In the last few years the airline industry had experienced a rapid growth within the low cost segment. The expenses for the airline companies have during the same period increased, mostly due to higher fuel prices and higher capital costs for airplanes. As a result of this, the economic situation for the airline companies has come to be very strained. The Swedish Civil Aviation Authority (LFV), wh

New technology is always coming and with that comes changes. The technology has made it easier to fulfil each customer's demand. The customer has today much more different products to choose between and the stores have problems to get the right product to the right place at the right time. It is hard for the supply chain to forecast what the customer is going to buy the next day, especially if

Background: Although advances in the treatment of myeloid neoplasms have led to improved patient survival, this improvement has been accompanied by an increased risk of second primary cancer (ie, the risk of another cancer after myeloid neoplasia). We aimed to assess bi-directional associations between myeloid cancers and other cancers—ie, development of second primary cancer in patients who have

Importance: Cancer is the second leading cause of death worldwide. Current estimates on the burden of cancer are needed for cancer control planning.Objective: To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 32 cancers in 195 countries and territories from 1990 to 2015.Evidence Review: Cancer mortality w

The general aim of the research programme SPEAK (Sustainable Planning andEnvironmental Assessment Knowledge, www.speakproject.se) was to generateknowledge on, and to strengthen the role of strategic environmental assessment(SEA) in planning as a measure to attain the environmental quality objectives andto promote sustainable development. The SPEAK programme had atransdisciplinary point of departur