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Rearrangements of the transcription factors FOS and FOSB have recently been identified as the genetic driver event underlying osteoid osteoma and osteoblastoma. Nuclear overexpression of FOS and FOSB have since then emerged as a reliable surrogate marker despite limitations in specificity and sensitivity. Indeed, osteosarcoma can infrequently show nuclear FOS expression and a small fraction of ost
Partially Premixed Combustion (PPC) is a combustion concept by which it is possible to get low smoke and NOx emissions simultaneously. PPC requires high EGR levels to extend the ignition delay so that air and fuel mix prior to combustion to a larger extent than with conventional diesel combustion. This paper investigates the operating region of single injection PPC for three different fuels; Diese
Non-exhaust sources, such as brakes, tyres, roads, and clutches, emit a large portion of airborne particles in road transportation, from ultrafine to coarse sizes. While airborne wear particle emissions from brakes and road-tyre contacts have been studied extensively, emissions from clutches have been overlooked. A preliminary study using a novel test rig has indicated that dry clutches also emit
Evacuation models commonly employ pseudorandom sampling from distributions to represent the variability of human behaviour in the evacuation process, otherwise referred to as ‘behavioural uncertainty’. This paper presents a method based on functional analysis and inferential statistics to study the convergence of probabilistic evacuation model results to inform deciding how many repeat simulation
Background: Breathlessness, the subjective sensation of breathing discomfort, is common and appears in the daily life of people with cardiorespiratory diseases. Physicians often rely on patient's history based on symptom recall. The relation between recalled and experienced breathlessness is still poorly understood. This paper presents the protocol for a study primarily aimed at evaluating the rel
This thesis addresses many issues surrounding the simple question: why have trams? With city populations exponentially growing alongside concerns over the environment and the economy, tramways have become a resurging form of sustainable transportation for municipalities. Once an endangered transportation mode, torn up and scrapped to make room for the age of cars, tramways are phoenix artifacts of
