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Background: Some, but not all, reports suggest that patients with Gaucher disease are at increased risk of developing malignancies, particularly hematopoietic tumors. The aim of this study was to assess the pattern of Gaucher disease and subsequent malignancies among male veterans admitted to US Veterans Affairs hospitals. Methods: Among 832 294 African American and 3 668 983 white male veterans w

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Objective To describe treatment patterns in the Swedish early psoriatic arthritis cohort (SwePsA) of the mono-/oligo-arthritic (M/O) and polyarthritis (P) and identify early predictive factors for treatment with disease-modifying anti-rheumatic (DMARD), non-steroidal anti-inflammatory drugs (NSAID), and tumour necrosis factor inhibition (TNFi) after 5 years. Methods Data for 198 M/O and P PsA were

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Background/Objective To demonstrate therapeutic equivalence of terbutaline via two different Turbuhaler® devices by evaluating its protective effect against methacholine-induced bronchoconstriction in stable asthma. Methods In this double-blind, double-dummy, multicentre, single-dose, 4-way crossover study, patients with stable mild-to-moderate asthma (FEV1 ≥80% predicted) were randomised to 0.5 o

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Popular AbstractAvhandlingen undersöker relationen mellan individer och platser relaterat till livskriser och existentiell trygghet. Författaren analyserar olika copingstrategier hos gravida kvinnor och hur detta förändrar deras relation till olika platser i deras livshistoria. Anthony Giddens begrepp ontologisk trygghet granskas kritiskt i förhållande till existentiell välmående och används sedanThe study explores the importance of place attachment on individuals? sense of security during existential crises. Coping strategies of pregnant women are analysed, focusing on how the prospect of giving birth affects their relationship to place. Anthony Giddens? concept of ontological security is critically examined and used to investigate the connection between place and ontological security ? w

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Many countries in Europe have experienced growing migration since World War II. It is estimated that more than one in five Swedes living today has roots in other countries and cultures. Segregation in terms of ethnic origin in housing areas makes it easier to maintain the language and cultural traditions of the home country when it comes to cooking and eating. In extremely segregated housing areas

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We used video-tracking of individuals of a Collembola, Protaphorura armata, on a clay surface in a petri dish to analyse their movement pattern in an environment with attractive and repellent cues. An area with dead conspecifics was repellent whilst live conspecifics made the area attractive. An area which had been occupied for 24 hours by the predatory mite, Hypoaspis aculeifer, was avoided only

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A transit is a phenomenon where a planet passes between its host star and an observer blocking out part of the light from the star. This decrease can be measured and used to gain information about the planet. The Kepler and TESS telescopes are examples of space telescopes using the transit method to detect exoplanets. For systems with more than one planet around the same star variations between th

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Cerebral Palsy (CP) is a disorder of movement that is caused before, during or soon after birth. CP affects movement and co-ordination caused by lack of muscle control by the brain [1], [2]. Stiff muscles, weak muscles, tremors and seizures as well as difficulties with swallowing are examples of symptoms in children with CP. Every year there are approximately 200 children born in Sweden that are a

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Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler (R) +tiotropium (TIO) HandiHaler (R) vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled corticosteroids/long-acting beta(2)-agonists (ICS/LABA). Methods: The cost-effectiveness analysis was based on the 12-week, randomised, double-blind CLIMB trial. The stud

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Introduction: To remain competitive, industrial organisations are continually faced with the challenges to improve product quality, reduce product development time, reduce production costs and lead-times. Increasingly, these challenges cannot be effectively met by isolated changes to specific organizational units. The Supply Chainis a revolutionary concept embedded in a traditional guise. In b

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As a complementary product to the Tetra Brik Aseptic packaging system, Tetra Pak is about to introduce a new, value added, aseptic packaging system called SCAP. The SCAP packages consists of a lower part made of carton and an upper part made of plastic, similar to a PET-bottle, resulting in a bottle shaped package. The purpose of this thesis is to design a logistical- and material-handling system

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In my paper I have compared popular science and neutral science regarding language and construction. My task was to find out if there are differences between the language of popular science and that of scientific science. The purpose of my paper is to answer four questions 1.How do the authors present the bogbodies and the mummies in the two categories? 2.What does the popular science imagine th

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Purpose: Within the construction business pricing is traditionally done at current account. The purpose of this report is to investigate why pricing levels are low within the construction consultant industry in comparison to other consultant industries, as well as to examine what affects the choice of pricing models. In addition to this the report aims to analyze pricing models used today and to d

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Identification of prostate gold fiducial markers in magnetic resonance imaging (MRI) images is challenging when CT images are not available, due to misclassifications from intra-prostatic calcifications. It is also a time consuming task and automated identification methods have been suggested as an improvement for both objectives. Multi-echo gradient echo (MEGRE) images have been utilized for manu

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Background: The rising prevalence of type 2 diabetes (T2D) poses a major global challenge. It remains unresolved to what extent transcriptomic signatures of metabolic dysregulation and T2D can be observed in easily accessible tissues such as blood. Additionally, large-scale human studies are required to further our understanding of the putative inflammatory component of insulin resistance and T2D.

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Background: Conduct disorder (CD), a serious behavioral and emotional disorder in childhood and adolescence, characterized by disruptive behavior and breaking societal rules. Studies have explored the overlap of CD with neurodevelopmental problems (NDP). The somatic health of children with NDP has been investigated; however, the prevalence of these problems in children with CD has not been suffici

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Background: Preterm birth has been shown to cause various long-term health issues. Children who were born preterm have also been observed to have more dental behaviour management problems (DBMP) during dental examinations and treatment than children born full term. It is known that dental radiographic examinations can be uncomfortable and cause anxiety in paediatric patients. Thus, our aims were t