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BACKGROUND: Niemann-Pick disease type C (NP-C) is a rare neurovisceral disease characterised by progressive neurological degeneration, where the rate of neurological disease progression varies depending on age at neurological onset. We report longitudinal data on functional disease progression and safety observations in patients in the international NPC Registry who received continuous treatment w
Energy efficiency ex-ante policy evaluation is commonly, but not exclusively, concerned with the simulation and modelling of policy instruments and resulting technological change. Using the residential sector as case study, the paper provides a meta-analysis of models and modelling exercises and scrutinise their relevance for the field of energy efficiency policy evaluation. The methodology of stu
Popular Abstract in Swedish Kärnan kan ses som en samling nukleoner vilka hålls samman av den starka kraften. Nukleonerna är protoner (p) med laddning +1 och neutroner (n) med laddning 0. Kraften kan beskrivas som ett utbyte av mesoner såsom pioner (pi) vilka förekommer i tre laddningstillstånd pi+, pi- och pi0 (laddning +1, -1 och 0). Inuti kärnan rör sig nukleonerna och utbytesmesonerna vilket gA comprehensive near-threshold 4He(g,n) absolute cross section measurement has been performed at the high-resolution tagged-photon facility MAX-lab located in Lund, Sweden. The 20 < Eg < 45 MeV tagged photons (covering the Giant Dipole Resonance energy region) were directed towards a liquid 4He target, and knocked-out neutrons were detected in a pair of 60 cm x 60 cm vetoed NE213A liquid scintilla
It is of great interest and importance how different amino acid residues contribute to and affect the properties of a protein surface, Partitioning in aqueous two-phase systems has the potential to be used as a rapid and simple method for studying the surface properties of proteins. The influence on partitioning of the surface exposed amino acid residues of eight structurally determined monomeric
Our everyday appliances ranging from toys to vehicles, as well as the equipment used to manufacture them, contain an increasing number of embedded computers. Embedded software often implement functionality that is crucial for the operation of the device, resulting in a variety of timing requirements and resource utilization constraints to be fulfilled. Industrial competition and the ever increasin
Background: The risk of sustaining a contra-lateral anterior cruciate ligament (C-ACL) injury after primary unilateral ACL injury is high. C-ACL injury often contributes to a further decline in function and quality of life, including failure to return to sport. There is, however, very limited knowledge about which risk factors that contribute to C-ACL injury. Objective: To systematically review in
INTRODUCTION: Administrative healthcare databases are useful to investigate the epidemiology, health outcomes, quality indicators and healthcare utilisation concerning peptic ulcers and gastrointestinal bleeding, but the databases need to be validated in order to be a reliable source for research. The aim of this protocol is to perform the first systematic review of studies reporting the validatio
Background and objectives: Neuroinflammation is implicated in the development and maintenance of persistent pain states, but there is limited data linking cerebrospinal fluid (CSF) inflammatory mediators with neurophysiological pain processes in humans. Study I aimed to investigate whether there are coherent changes in CSF inflammation associated with central sensitization (CS), and to evaluate po
Introduction: The presence of fibrillatory waves (f-waves) is important in the diagnosis of atrial fibrillation (AF), which has motivated the development of methods for f-wave extraction. We propose a novel approach to benchmarking methods designed for single-lead ECG analysis, building on the hypothesis that better-performing AF classification using features computed from the extracted f-waves im
IMPORTANCE: Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important.OBJECTIVE: To describe rates of low-grade (grade group 1) and high-grade (grade groups 2-5) prostate cancer identified among men invited to participate in a prostate cancer screening protocol consisting of a PSA test, a 4-ka
Importance: Recent studies have questioned the presumed low-risk status of patients with asymptomatic nonsevere aortic stenosis (AS). Whether annual N-terminal pro-brain natriuretic peptide (NT-proBNP) measurements are useful for risk assessment is unknown. Objective: To assess the association of annual NT-proBNP measurements with clinical outcomes in patients with nonsevere AS. Design, Setting, a
Background: Exposure and Response Prevention (ERP) is a form of behavioural therapy for tics; however, its effectiveness remains uncertain. We aimed to evaluate the effectiveness of internet-delivered, therapist-supported, and parent-assisted ERP for treatment of tics in children and young people with Tourette syndrome or chronic tic disorder. Methods: This multicentre, parallel group, single-blin
BACKGROUND: The Swedish school-based vaccination programme offers HPV vaccine to girls born ≥1999 in 5-6th grade. In 2012, all counties introduced free-of-charge catch-up vaccination campaigns targeting girls born 1993-1998. Varying vaccine uptake in the catch-up group by December 2012 suggested that some implementation strategies were more successful than others. In order to inform future vaccina
As of 2014, villages in the provinces where metropolitan municipalities ruled in Turkey have been transformed into the status of neighborhood administration and the practice of providing services to rural settlements has been started by municipalities. Significant exceptions and exemptions had to be granted for five years in order to protect rural dwellers against local obligations. However, after
Urban trees are uniquely valuable in towns and cities for the ecosystem services they provide their citizens and can as such be considered a potent source of public goods and positive externalities - even when these trees are found on private properties. The importance of urban trees will only grow as events of severe heat and extreme rainfall become more and more frequent and the urgency to reduc
The failure of many countries in the Global South to catch up economically to the advanced economies of the Global North has long been a topic of interest to economic historians and development economists. Traditionally, researchers focused their attention on the question of growth –how can a country achieve growth to catch up? In recent years, however, a new research programme has begun to shift
1 Rules of Procedure for MultiPark MultiPark is a strategic research area (SRA) at Lund University (LU). MultiPark is under the main leadership of LU´s Vice Chancellor (Universitetsrektor), and it is internally led by a Board. According to LU´s guidelines, the Board is to establish written rules of procedure for their work. The rules of procedure can be revised, upgraded, and complemented when nec
Humour Now and Then: Aristophanes vs. Terry Pratchett Humour Now and Then: Aristophanes vs. Terry Pratchett Yvonne Borowski M.A. University of Lodz „ We do not laugh now as people once laughed. Therefore, it is hardly possible to give a general philosophical definition of the comic and of laughter: such a definition can be only historical.” Vladimir Propp Theory and History of Folklore, Eng. tr. A
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HILMA HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 31, 2005/06, Nr 3, 2005-10-10 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansökningsblanketter i förekommande fall. De sistnämnda kopierar du och sätter tillbaka originalet i pärmen! VENTILERING
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