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Optimal Pressure Management in Water Distribution Systems : Efficiency Indexes for Volumetric Cost Performance, Consumption and Linear Leakage Measurements

Water is a finite resource and should be given the attention it deserves to reduce its depletion through leakages in pipe systems. The authors implemented pressure management strategies linked to fixed and variable discharge (FAVAD), the burst and background estimate (BABE), and orifice principle methodologies to analyze a two-phased comparative method for applying optimal pressure management and

A large cohort study of the effects of Lewis, ABO, 13 other blood groups, and secretor status on COVID-19 susceptibility, severity, and long COVID-19

Background: Previous studies have reported Blood type O to confer a lower risk of SARS-CoV-2 infection, while secretor status and other blood groups have been suspected to have a similar effect as well. Study design and methods: To determine whether any other blood groups influence testing positive for SARS-CoV-2, COVID-19 severity, or prolonged COVID-19, we used a large cohort of 650,156 Danish b

Effects of Levodopa-Carbidopa Intestinal Gel on Dyskinesia and Non-Motor Symptoms Including Sleep : Results from a Meta-Analysis with 24-Month Follow-Up

Background: In advanced Parkinson's disease (PD), dyskinesias and non-motor symptoms such as sleep dysfunction can significantly impair quality of life, and high-quality management is an unmet need. Objective: To analyze changes in dyskinesia and non-motor symptoms (including sleep) among studies with levodopa-carbidopa intestinal gel (LCIG) in patients with advanced PD. Methods: A comprehensive l

Developing your doctoral thesis

Structure of the thesisThe structure of the doctoral thesis should be that of a so-called compilation thesis. That is, a summary of scientific articles written by the PhD student alone or jointly with one or more other people [with the articles appended after the summary]. Theses in the form of one unified, coherent scientific work (monograph thesis) may be allowed as an exception, following a spe

https://www.intramed.lu.se/en/phd-studies/admission-examination/doctoral-degree/public-defence/developing-your-doctoral-thesis - 2026-05-29

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

Background: The K3326X variant in BRCA2 (BRCA2∗c.9976A>T p.Lys3326∗rs11571833) has been found to be associated with small increased risks of breast cancer. However, it is not clear to what extent linkage disequilibrium with fully pathogenic mutations might account for this association. There is scant information about the effect of K3326X in other hormonerelated cancers. Methods: Using weighted lo

Biocatalyst Engineering: Metabolic Engineering, Kinetic modeling and metagenomics applied to industrial biotechnology

Industrial biotechnology has been defined as the use and application of biotechnology for the sustainable processing and production of chemicals, materials and fuels. It makes use of biocatalysts such as microbial communities, whole-cell microorganisms or purified enzymes. Although biocatalysts are considered advantageous, since they operate under mild conditions regarding temperature and pH and e

Contractility, ventriculoarterial coupling, and stroke work after acute myocardial infarction using CMR-derived pressure-volume loop data

Background: Noninvasive left ventricular (LV) pressure-volume (PV) loops derived by cardiac magnetic resonance (CMR) have recently been shown to enable characterization of cardiac hemodynamics. Thus, such PV loops could potentially provide additional diagnostic information such as contractility, arterial elastance (Ea) and stroke work (SW) currently not available in clinical routine. This study so

Increased carotid intima-media thickness in patients with radiographic axial spondyloarthritis compared to controls and associations with markers of inflammation

Objective: There is an increased risk for cardiovascular disease (CVD) in patients with radiographic axial spondyloarthritis (r-axSpA). In this cross-sectional study, we aimed to, overall and stratified by sex, (i) compare ultrasound derived carotid intima media thickness (cIMT), between patients and controls, and (ii) investigate associations between cIMT, clinical disease activity and inflammati

Large discrepancy between future demand and supply of agricultural water in northwestern Iran; evidence from WEAP-MODFLOW-machine learning under the CMIP6 scenario

The agricultural sector in northwestern Iran uses about 95 % of the region's available water resources and nearly 98 % of are aquifer water. Despite the regiońs previous richness in water resources, the supply is now quickly decreasing. The Ghorveh-Dehgolan sub-basin in northwestern Iran consists of three dams as well as three aquifers that supply water resources for agriculture, domestic uses, an

High-grade Vesicoureteral Reflux in Patients With Anorectal Malformation From the ARM-Net Registry : Is Our Screening Sufficient?

Background: Vesico-ureteral reflux (VUR) is a common associated urological anomaly in anorectal malformation (ARM)-patients. High-grade VUR requires antibiotic prophylaxis to prevent urinary tract infections (UTI's), renal scarring and -failure. The exact prevalence of high-grade VUR in ARM patients is unknown. Hence, the aim of this study was determining the incidence of high-grade VUR in ARM-pat

CHEOPS observations of KELT-20 b/MASCARA-2 b: An aligned orbit and signs of variability from a reflective day side

Context. Occultations are windows of opportunity to indirectly peek into the dayside atmosphere of exoplanets. High-precision transit events provide information on the spin-orbit alignment of exoplanets around fast-rotating hosts. Aims. We aim to precisely measure the planetary radius and geometric albedo of the ultra-hot Jupiter (UHJ) KELT-20 b along with the spin-orbit alignment of the system. M

Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study

Introduction Aggrecanase cleavage at the (392)Glu-(393)Ala bond in the interglobular domain (IGD) of aggrecan, releasing N-terminal (393)ARGS fragments, is an early key event in arthritis and joint injuries. Here, we use a quantitative immunoassay of aggrecan ARGS neoepitope fragments in human synovial fluid to determine if this cleavage-site specific method better identifies joint pathology than

Constraint-induced movement therapy in patients with stroke: a pilot study on effects of small group training and of extended mitt use

Objective: (1) To evaluate constraint-induced movement therapy for chronic stroke patients modified into group practice to limit the demand on therapist resources. (2) To explore whether extended mitt use alone may enhance outcome. Design: A combined case-control and randomized controlled study with pre- and post-treatment measures by blinded observers. Setting: A university hospital rehabilitatio

Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells

The association of L-type Ca(2+) channels to the secretory granules and its functional significance to secretion was investigated in mouse pancreatic B cells. Nonstationary fluctuation analysis showed that the B cell is equipped with <500 alpha1(C) L-type Ca(2+) channels, corresponding to a Ca(2+) channel density of 0.9 channels per microm(2). Analysis of the kinetics of exocytosis during voltage-

I ZONEN - Framtida lärandemiljöer för yngre tonåringar i en urban kontext

Hur bör de senaste decenniernas utveckling inom IT och pedagogik påverka utformningen av nya lärandemiljöer? Kan skolarkitektur bidra till att främja god fysisk och psykisk hälsa? Arbetssätt och målsättningar har ändrats mycket inom den svenska skolan under de senaste decennierna. Informationsteknologi har i grunden ändrat tillgängligheten till information och påverkat hur vi både arbetar och koHow should the technological and pedagogical development during the last few decades affect the design of new schools? Can school architecture contribute to good physical and mental health in young teenagers? The way of working and targets for what the students should achieve have changed a lot in Sweden during the last few decades. Information technology has fundamentally changed the ease of ac

Utlysning POSTDOC Stipendium J Bengzon

Postdoc J Bengzon 2025 September 3, 2024 Page 1 ( 3) Depar tment of Cl in ica l Sciences , Lund Scholarsh ip coordina tor Dnr: V 2024/1741 Announcement of a Postdoc Scholarship at the Department of Clinical Sciences Lund, division of Neurosurgery Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has around 46 000 students and more t

https://www.intramed.lu.se/sites/intramed.lu.se/files/2024-09/Utlysning%20POSTDOC%20stipendium%20J%20Bengzon.pdf - 2026-05-30

B-form baseline

Formulär B Frågeformulär B GÅS Gott åldrande i Skåne Så här fyller Du i frågeformuläret: De f lesta frågorna besvaras med ett kryss för det svars- alternativ som bäst stämmer in på Dig själv. I några fall kan Du kryssa i flera svarsalternativ på samma fråga. I så fall står det angivet direkt efter frågan. Om Du undrar över något i formuläret står vi gärna till tjänst med upplysningar. Du kan nå os

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/b-form_baseline.pdf - 2026-05-30

Gas nyhetsbrev 2020

Nyhetsbrev 2020 till dig som deltar i ett världsunikt projekt Vi som arbetar med Gott åldrande i Skåne Som deltagare i studien Gott åldrande i Skåne (GÅS) kommer man i första hand i kontakt med de team som arbetar med undersökningarna: läkare, sjuksköterska, testledare och medicinsk sekreterare. Men projektet sysselsätter även andra yrkesgrupper som spelar en viktig roll vid hanteringen av all den

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/gas_nyhetsbrev_2020.pdf - 2026-05-30