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Aim. The epidemiology of critical limb ischemia (CLI) is insufficiently studied, and treatment of risk factors for atherosclerosis has received less attention in CLI patients than in patients with coronary or precerebral atherosclerosis. The aim of this study was to establish the incidence of CLI and the quality of risk factor treatment in Swedish CLI patients. Methods. During 14 months, 316 conse
The bachelor thesis was to create a GPS tracking system for Svep Design Center AB. The system would consist of two major parts which were linked together through a common database. One part consisted of a cell phone application were the user can transmit their current position and the other part was a web application where the position data is presented on a map outlining the route of the user. Si
Lifestyle modifications could be crucial in preventing and managing type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD), including diet and postprandial glycaemic control. Previous studies on the effects of polar lipids (PLs) on postprandial metabolic responses at Lund University have shown conflicting results. To reconcile these findings and contribute to the existing literature, th
Introduction Systemic inflammation is postulated to mediate heat stroke and heat-related organ injury, yet acute inflammatory responses among heat-stressed workers remains poorly understood. We aimed to describe neutrophil mobilisation and potential release of DNA during heat stress in multiple hot occupational settings and a controlled experimental setting. Methods Neutrophil:lymphocyte ratio (NL
Objectives: Panax ginseng (P. ginseng, C.A. Meyer) is suggested to improve blood glucose regulation, but evidence remains inconsistent. We examined whether consuming P. ginseng as a preload before a carbohydrate-rich meal modulates postprandial glucose and insulin responses. Methods: In a randomized, double-blind, crossover trial, 22 healthy middle-aged adults consumed P. ginseng tablets containin
BACKGROUND/AIM: Determining the causation of an injury in living individuals is a key task for forensic pathologists. However, little is known about sex-based differences in injury characteristics. The study aims to examine sex-based differences in single stab injuries to the trunk among assault survivors, to potentially identify injury patterns that could aid forensic assessment and help in the m
BACKGROUND: Early HIV diagnosis allows timely interventions to control HIV transmission. We have determined the proportion of recent infections among people living with HIV (PLHIV) enrolling to care in Ethiopia and identified factors associated with recent infection. METHODS: Participants (aged ≥ 15 years) newly enrolled in HIV care were recruited from urban clinics in central Ethiopia (2022-2024)
Process-based biosphere models, which formulate biophysical ecosystem processes, provide a mechanistic framework for understanding terrestrial carbon dynamics. In contrast, data-driven approaches, e.g., upscaling eddy covariance (EC) fluxes using satellite observations and machine learning, offer empirical estimates. These complementary methods often diverge significantly, particularly in estimati
Contemporary organizations expect newly formed teams to perform from the outset under strict time and task constraints. While Wheelan’s (1994a; 2005) Integrated Model of Group Development (IMGD) frames team development as a progression through distinct stages, few studies have examined whether such assumptions are reflected in the temporal structure of early interaction. Drawing on a dynamic syste
As mass timber construction gains momentum worldwide, cross-laminated timber (CLT) has emerged as an important material in the built environment. However, the combustible nature of wood presents challenges and fire safety concerns, and a key interest with respect to CLT is the adhesive bond line. CLT is commonly used in ceiling configuration, and current fire stability evaluations rely predominant
Utländska direktinvesteringar är viktiga för tillväxt och sysselsättning, men kan samtidigt innebära risker för EU:s säkerhet eller allmänna ordning. Mot denna bakgrund antogs Europaparlamentets och rådets förordning (EU) 2019/452 om granskning av utländska direktinvesteringar (FDI-förordningen), som etablerade en unionsgemensam ram för granskning av investeringar som kan påverka säkerhet eller alWhile foreign direct investment (FDI) is important for growth and employ-ment, it may also pose risks to security or public order in the EU. To address these concerns, Regulation (EU) 2019/452 of the European Parliament and of the Council on the screening of foreign direct investments (FDI Regulation) was adopted, establishing a common EU framework for the screening of investments that may affect
This thesis presents a complete digital back-end implementation of a PN-dither least-mean-squares (LMS) background calibration scheme for a 12-bit, 500 MS/s pipeline analog-to-digital converter (ADC). The target converter, designed by a parallel analog project, comprises four 3-bit stages and a 4-bit final flash stage; its actual inter-stage gains depart substantially from their nominal values, re
Background: Polygenic risk scores (PRSs) strongly discriminate for prostate cancer risk at the population level. The role of these genetic scores in determining prostate cancer survival is unclear, potentially due to methodological issues. Methods: We included 19,607 men from the Malmö Diet and Cancer Study (MDCS) and the Health Professionals Follow-up Study (HPFS) and analyzed 20-year incidence a
Anxiety disorders are common in children and adolescents, but constrained resources limit access to cognitive-behavioral therapy (CBT). Stepped and stratified care models offer different ways to organize care. Stepped care starts with lower-resource CBT and escalates when needed, whereas stratified care matches CBT format to patient complexity from the outset. Economic evidence comparing these mod
Objective: To evaluate if postnatal treatment with betamethasone in extremely preterm infants was associated with neurodevelopmental impairment (NDI) at 6.5 years of age. Design: Prospective cohort study. Setting: Extremely Preterm Infants in Sweden Study (gestational age <27 weeks, born 2004-2007). Patients: 428 children born extremely preterm were assessed at 6.5 years of age, 115 treated with b
Land use/vegetation cover change, reflecting a range of human land use practices, is the most prevalent and immediate influence on alterations in soil quality. The physical structure of soil is crucial for safeguarding soil carbon (C) and nitrogen (N), as it modulates the physical protection mechanisms and the distribution of these elements within the soil. Nevertheless, the impact of soil physica
BACKGROUND: Previous post hoc analyses of clinical trials have suggested that a higher percentage of systolic blood pressure time in target range (SBP-TTR) was associated with a decreased risk of cardiovascular disease (CVD). However, there is limited evidence from large prospective cohort studies on the relationship between long-term SBP-TTR and the risk of CVD.OBJECTIVES: The purpose of this stu
INTRODUCTION: Low birth weight is an important measure of the health of pregnant women and newborns. We investigated the prevalence of low birth weights in India over nearly three decades to assess trends and convergence across states.METHODS: Data came from five waves of the National Family Health Survey (1992-93 to 2019-21). The prevalence of low birth weight was estimated. To explore the sensit
Background: There are currently no molecular tests to identify individual breast cancers where radiotherapy (RT) offers no benefit. Profile for the Omission of Local Adjuvant Radiotherapy (POLAR) is a 16-gene molecular signature developed to identify low-risk cancers where RT will not further reduce recurrence rates. Methods: An individual participant data meta-analysis was performed in 623 patien
