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Basic Concepts and Modelling Methods

Try to imagine a fire emergency evacuation. What is the first image that you have in your mind? Here there are some guesses. Probably a parent running inside a house trying to rescue her children, but not managing since she is too scared? An old man stuck crying in a corner of a room with flames and smoke all around him? Or a group of people crushing aggressively against each other in order to get

Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix

Background: Epidemiological studies have shown that many welders experience respiratory symptoms. During the welding process a large number of airborne nanosized particles are generated, which might be inhaled and deposited in the respiratory tract. Knowledge of the underlying mechanisms behind observed symptoms is still partly lacking, although inflammation is suggested to play a central role. Th

Breastfeeding as a balancing act - Pregnant Swedish women's voices on breastfeeding

Background: Breastfeeding provides health benefits to both women and children. The rationale behind an individual woman's decision to breastfeed or not can depend on several factors, either independently or in combination. The aim of the current study was to explore attitudes towards breastfeeding among pregnant women in Sweden who intend to breastfeed. Methods: Eleven mothers-to-be, one of whom h

'Fighting an uphill battle' : a qualitative study of the challenges encountered by pharmacy workers when providing services to men who have sex with men in Dar es Salaam, Tanzania

BACKGROUND: Previous research suggests that Tanzanian MSM might prefer consulting pharmacies and drugstores, rather than public healthcare services, when in need of STI medicines and treatment. Yet, few studies have explored the experiences of providing services to MSM clients among those working at pharmacies and drugstores and examined what challenges they encounter in providing these services.

Timing of the deglaciation in southern Patagonia: Testing the applicability of K-Feldspar IRSL

The timing of the ice margin retreat of the Late Glacial Patagonian Ice Sheet (PIS) in southern Patagonia has been the object of discussion for many years. In order to resolve questions about the complex response of the PIS to past climate change, any geological interpretation and data modelling need evaluation against an absolute chronology. The aim of this project is to investigate the applicabi

Features of cortical neuroplasticity associated with multidirectional novel motor skill training: a TMS mapping study

Given the evidence that the primary motor cortex (MI) consists of subpopulations of upper motor neurons tuned to different directional parameters of a motor movement, this study hypothesized that novel motor skill training involving either a bidirectional or more complex multidirectional tongue-typing movement should produce distinct training-related features of tongue MI neuroplasticity in humans

WTS-2 b: a hot Jupiter orbiting near its tidal destruction radius around a K dwarf

We report the discovery of WTS-2 b, an unusually close-in 1.02-d hot Jupiter (M-P = 1.12M(J), R-P = 1.30R(J)) orbiting a K2V star, which has a possible gravitationally bound M-dwarf companion at 0.6 arcsec separation contributing similar to 20 per cent of the total flux in the observed J-band light curve. The planet is only 1.5 times the separation from its host star at which it would be destroyed

Molecular Classification of Bladder Cancer

Popular Abstract in Swedish Cancer i urinblåsan är ett stort hälsoproblem i Sverige och världen. Det är den femte vanligaste cancerformen i Sverige och är den som belastar sjukvården med högst kostnader per patient. Ungefär tre fjärdedelar av de drabbade är män och patienterna är oftast kring 60-80 år gamla. Den behandling vi idag kan erbjuda en person som drabbas av blåscancer har inte förändratsDecisions in the treatment of bladder cancer today are based on clinical and pathological risk variables such as tumor stage and tumor grade. The importance of these conventional risk variables is well documented since more than 10 years, and they are used routinely in the clinics. Over the last ten years, cancer research has seen a gradual transition towards personalized medicine, i.e. the exploi

Evaluation of image reconstruction methods for 123I-MIBG-SPECT: a rank-order study.

Background: There is an opportunity to improve the image quality and lesion detectability in single photon emission computed tomography (SPECT) by choosing an appropriate reconstruction method and optimal parameters for the reconstruction. Purpose: To optimize the use of the Flash 3D reconstruction algorithm in terms of equivalent iteration (EI) number (number of subsets times the number of itera

Differential migration in raptors

Differences between ages, sexes and populations in the timing of migration at Falsterbo, Sweden and in the choice of wintering site among raptors in Scania were investigated. Competition and dominance is the best primary explanation to the results. In most cases the more competitive adults winter north of juveniles and the larger females north of males. Moult strategy is probably one of the most i

The Needs for Microtraining, Learning objects and Open Educational Resources in GIS

With today’s rapid changes in socio-economy and technology, knowledge and learning are critical issues for private and civil service organizations. The needs for competence development range from short informal courses (without ECTS credits) to formal courses at university level (with ECTS credits). This article describes objectives and results of a Leonardo project, eGIS+ that developed and imple

Obesity in a Rural Population Experiences from The Skaraborg Project

Over the last two decades there has been a striking and continuous increase in the prevalence of obesity both in industrialized and developing countries. Despite this global consistency there is a variation within countries with a higher prevalence of obesity within rural areas. The overall aim was to explore the prevalence of obesity and factors that influence the development of obesity in a rura

Rapid growth of gas-giant cores by pebble accretion

The observed lifetimes of gaseous protoplanetary discs place strong constraints on gas and ice giant formation in the core accretion scenario. The approximately 10-Earth-mass solid core responsible for the attraction of the gaseous envelope has to form before gas dissipation in the protoplanetary disc is completed within 1-10 million years. Building up the core by collisions between km-sized plane

The Performance of a Dual Fuel HCCI Engine

The HCCI engine has shown great qualities such as high efficiency combined with low emissions. However, many issues have not totally been solved yet. One way to control the combustion timing, one of the commented issues, is dual fuel utilizing the difference in ignition temperature between different fuels. So, from this point on it is not difficult to think about developing a big mapping of one H

Indication of cracking during pressing of advanced thin plates using an AE-based monitoring system

The acoustic emission that is detectable in the forming of complex thin part plates contains information about the quality of the pressed plates. The information can be used as process control and to filter out advanced thin plates with defects such as cracks. The article describes the results obtained in a try-out pressing process in special developed punch-die pairs with different pressing

Cygnet or ugly duckling – what makes the difference? A tale of heat-pump market developments in Sweden

Who can pick a winner? Since 1974, various types of targeted support have at different times been directed at the development of the heat pump market in Sweden – which in the following decades oscillated violently between soaring sales and collapse. Eventually, however, small heat pumps for space heating of residential buildings have in recent years securely established themselves as a mature and

Concentrated DNA-amphiphiles Structure, Hydration, and Dynamics

Popular Abstract in Swedish DNA är en molekyl som finns närvarande i stan alla celler och den innehåller den genetiska koden för utvecklingen av alla former av liv. Molekylen är väldigt tunn (2 nanometer i diameter) och lång - mänskligt DNA skulle vara ca en meter lång i utsträckt tillstånd. Inuti cellerna antar DNA en superkompakt struktur för att få plats inuti en cellkärna med bara ca 10 mikromThe structure, hydration, and dynamics of concentrated DNA-amphiphile complexes were investigated by small-angle X-ray diffraction, sorption calorimetry, and nuclear magnetic resonance. A concentrated, electroneutral, DNA-amphiphile complex can be formed by mixing charge-stoichiometric solutions. The effect is a strong association of DNA with the oppositely charged amphiphile resulting in the form

The Long-term Durability of Intra-operatively Placed Palmaz Stents for the Treatment of Type Ia Endoleaks After EVAR of Abdominal Aortic Aneurysm

Objective/Background The objective was to analyze the long-term durability of intra-operatively placed Palmaz stents for type Ia endoleaks, and the evolution of aneurysm neck morphology. Methods This was a retrospective cohort study conducted at a tertiary referral centre. Patients treated between 1998 and 2012 were reviewed with regard to pre-, intra-, and post-operative data. Crude and relative

Earlier occurrence and increased explanatory power of climate for the first incidence of potato late blight caused by Phytophthora infestans in Fennoscandia

Background Late blight (caused by Phytophthora infestans) is a devastating potato disease that has been found to occur earlier in the season over the last decades in Fennoscandia. Up until now the reasons for this change have not been investigated. Possible explanations for this change are climate alterations, changes in potato production or changes in pathogen biology, such as increased fitness o

A calcium sulphate/hydroxyapatite ceramic biomaterial carrier for local delivery of tobramycin in bone infections : Analysis of rheology, drug release and antimicrobial efficacy

Local targeted treatment of bone and joint infections using antibiotic-containing carriers is a common practice today. A recently FDA approved biphasic calcium sulphate/hydroxyapatite (CaS/HA) carrier containing gentamicin has been reported to give a sustained drug release, highly effective in eradicating bone infections. We present the first study evaluating the widely used aminoglycoside tobramy