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Molecular Interrogation and Functional Studies of Acute Leukemia

Hematological malignancies are defined by their underlying genetic alterations, many of which are used to diagnose patients to classify them to different risk groups that dictate the therapy given. Recent advances in high-throughput sequencing have highlighted the presence of co-occurring genetic lesions and that they may form distinct genetic clones that evolve throughout disease progression. Acu

Present European and Scandinavian Co-production Practices Through the Prism of The Girl with the Dragon Tattoo (2009).

In a critique of the sometimes confusing ways in which the term transnational has been repeatedly used, Mette Hjort, in 2010 attempted to outline what she called a “typology of transnationalisms” in connection with contemporary audio-visual production (2010: 12–33). Hjort’s palpable purpose here was to more precisely illuminate and contextualize the increasingly used concept of transnationalism. A

Advancing Software Development Efficiency in an Open Source Software Context

Open source software has been gaining popularity, especially among commercial organizations. The broad industry acceptance is in large part due to the demonstrated ability of open source solutions to compete with proprietary alternatives. Using open source software components enables companies to reduce their own development costs, and thus improve software development efficiency. Many open source

Developing internal crisis communication: New practices for communication professionals

Purpose - The article has two major purposes. The first purpose is to examine the roles and practices of communication professionals in relation to internal aspects of crisis communication. The second purpose is to suggest new roles and practices for communication professionals that will enable a strategic approach to internal crisis communication. This article is based on empirical material from

Health-Related Quality of Life and Adherence in Haemophilia

Assessment of health-related quality of life (HRQoL) in haemophilia is important in order to provide information for clinical decision making and to verify the impact of haemophilia on patients and their families. Advances in haemophilia care and prophylactic treatment have improved HRQoL for the patients and where treatment is available, patients with haemophilia have almost reached the same life

Barn i anstalt - en komparativ studie om barn till frihetsberövade föräldrar i Norden

Under början av 1900-talet införde alla nordiska länder, förutom Norge, en möjlighet för frihetsberövade kvinnor att medföra sitt spädbarn i anstalten under straffverkställigheten. Regleringarna grundades på arvsbiologiska aspekter, då det var vanligt att de små barnen fortfarande ammades av sina mödrar och de var beroende av modersmjölken för att överleva. Med tiden har dock regleringarnas syfte In the beginning of the 20th century all Nordic countries except Norway introduced a possibility for imprisoned women to bring their infants with them during their sentence. The legislation was considered necessary due to the fact that the infant still was breast-fed by their mother. Child psychologist and psychoanalysist John Bowlby (from Great Britain) developed the affiliation theory during th

Arbete är vägen till frihet – en studie om arbetsförmedlares syn på sitt nya integrationsuppdrag

Abstract Author: Moa Nordberg Title: Arbete är vägen till frihet – en studie om Arbetsförmedlares syn på sitt nya integrationsuppdrag Supervisor: Carina Tigervall Examiner: Staffan Blomberg The integration work in Sweden has during the last years undergone a reformation process and in December 2010 a new law came into forces. With the new law the government 2006-2010 aims to reform the integrati

Tillgång till elektroniska hälsodata - på bekostnad av konfidentialitet? - Om sekundäranvändning enligt den europeiska hälsodataförordningen och skyddet för företagshemligheter

Elektroniska hälsodata produceras, insamlas och används idag av ett stort antal olika typer av aktörer inom EU. Tillgången till och delningen av denna elektroniska hälsodata anses utgöra ett led i att såväl förbättra hälso- och sjukvården inom unionen som för främjandet av exempelvis innovation och forskning. För att kunna förverkliga den fulla potential denna elektroniska hälsodata innehar inrättElectronic health data are currently produced, collected and used by a wide range of actors within the European Union. Access to and sharing of such data are regarded as instrumental in both improving healthcare within the Union and in promoting, inter alia, innovation and research. In early 2025, through the European Health Data Space Regulation, a framework governing the use and exchange of such

InP/InAsP Quantum Discs-in-Nanowire Array Photodetectors: Design, Fabrication and Optical Performance

This thesis focuses on processing and electro-optical investigations of two- and three-terminal photodetectors based on large arrays of around three million n+-i-n+ InP nanowires with embedded InAsP quantum heterostructures for broadband detection. First, we investigated the optoelectronic behavior of two-terminal photodetectors under selective 980 nm excitation of the 20 axially embedded InAsP qu

European stroke organisation and European society for minimally invasive neurological therapy guideline on acute management of basilar artery occlusion

The aim of the present European Stroke Organisation (ESO) guideline is to provide evidence-based recommendations on the acute management of patients with basilar artery occlusion (BAO). These guidelines were prepared following the Standard Operational Procedure of the ESO and according to the GRADE methodology. Although BAO accounts for only 1%–2% of all strokes, it has very poor natural outcome.

High Concentration in the European Audit Market: In the Public Interest?

Background and problem: By examining the problems and measures of audit market concentration in the Commission’s Green paper and the audit professions responses to the Green paper it can be seen that they have different opinions. The Commission greatest concern seems to be the highly concentrated audit market and that this will affect the auditor independence. The audit profession appears to agree

Hidden Markov models - Traffic modeling and subspace methods

The main motivation for this thesis, however not the only one, is the search for models for traffic in telecommunication networks. Traffic characterization and modeling are of great importance in the analysis and dimensioning of communication systems. During the last decades we have experienced an explosive growth of our telecommunication networks. New important properties, both on macroscopic and

Evaluation, Experience and Potential of Gas Turbine Based Cycles with Humidification

Gas turbines, in simple and combined cycle, are common and economically profitable on the power generating market today. Several new cycles have been proposed as future competing technologies, but all studies about these cycles have, so far, been paperwork. The requirements for these new cycles are better efficiency than those of today, provide better flexibility, offer short start up times, less

Effects of Past and Current Land Use on Biodiversity: from a semi-natural grassland on Öland (Sweden) to a European perspective

Popular Abstract in French L'inquiétude grandit quant à la perte de la biodiversité liée aux changements d'utilisation des terres, l’effet de cette perte sur les services écosystémiques fournis par les communautés naturelles et semi-naturelles et, finalement, la menace que cela pourrait entraîner sur le bien-être de l’Homme. Ce travail de thèse examine l'impact de l'utilisation des terres présenteConcerns are increasing about the loss of biodiversity under land use change and how this will affect the ecosystem services provided by natural and semi-natural communities and consequently how this will threaten human well-being. The thesis examines the impact of present and past land use on different aspects of biodiversity; namely species diversity, traits and functional diversity and on ecos

Phenotypic responses of zooplankton to variable conditions

Organisms are continually challenged by multiple threats in the environment, and such threats are seldom constant in either time or space. Therefore, organisms must maintain physiological, behavioural, morphological and life- history adaptations across environments to prevent reductions in fitness. Freshwater ecosystems are particularly variable environments, and so organisms inhabiting lakes and

The Challenges of Experience Sampling Method in a Qualitative Study on Tourist Information Behaviour on Smartphones

Background of the study One of the main challenges in tourism research is to find effective methodologies to capture the salient moments that make a tourist experience memorable (Cary, 2004; Tussyadiah, 2014). A gap exists between the tourist experience – which happens at a destination, during the time of the trip – and the recollection of it during the study – which often happens days, weeks or m

Determinants of persistent asthma in young adults

Objective: The aim of the study was to evaluate determinants for the prognosis of asthma in a population-based cohort of young adults. Design: The study was a nine-year clinical follow up of 239 asthmatic subjects from an enriched population-based sample of 1,191 young adults, aged 20-44 years, who participated in an interviewer-administered questionnaire and clinical examination at baseline in 20

Survey on opportunities and barriers in lighting controls

This report summarizes a survey performed in eight countries on the status quo of daylight and electric lighting control systems. Feedback from more than 100 international experts (building / facility managers and planers) was evaluated. The aim of the survey was to identify the perception of the different possibilities of the current lighting control solutions and the expectations about the contr

Multi-objective Optimization and GIS to Improve Climate Change Induced Disaster Risk Management in Africa

We live in an era that suffers from climate change issues, not least disaster risks induced by climate change. While measures, such as proper evacuation plans, are required to reduce the negative impacts of disasters when they hit, actions should also be taken to reduce climate change effects by e.g. increasing the use of renewable energies or proper urban land-use allocation, where climate change

Nödvärnsrättens gränser vid angrepp mot person - Om rättspolitiska överväganden i lag och praxis

Denna uppsats undersöker gränserna för ansvarsfriheten vid våld utövat i nödvärn enligt svensk rätt och granskar de rättspolitiska överväganden som ligger till grund för gränsdragningarna i lag och praxis. Framställningen är avgränsad till angrepp mot person och behandlar inte straffmätningen vid överskriden nödvärnsrätt. En grundläggande förutsättning för ansvarsfrihet är att rätt till nödvärn fThis paper examines the Swedish law relating to the limits of violence applied when exercising self-defence and explores the prescriptive considerations underlying law and practice. The exposition is delimited to assaults against individuals and does not cover questions regarding leniency of punishment. A basic condition for freedom of responsibility is the existence of a right of self-defence. S