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Exploring emotional relationships between user and product is an important issue to adress in the design of t non-discriminating everyday products. Universal design is one approach among several, which the industrial designer can use when designing on the basis of on a non-discriminating philosophy. One way to achieve an integration of the user product relationship into the concept of universal de
A method has been developed that automatically constructs a crystallographic refinement force field (topology and parameter files) for any molecule from a theoretical frequency calculation. The approach has been tested on five proteins containing metal sites or non-standard inhibitors or coenzymes and it is shown that the structures are improved in various aspects.
In time-selected migration birds adapt their fuel deposition and flight behaviour to maximise sustained migration speed. What are the expectations for the final part of spring migration when the transition to breeding takes place and the criterion of a maximum total migration speed is no longer relevant? Two possible strategies representing different ends of the capital – income spectrum are evalu
The aim of the project has been to elucidate molecular events leading to amyloidosis in Hereditary Cystatin C Amyloid Angiopathy (HCCAA) patients, to enable simple diagnosis of the disease and with the ultimate goal to understand the amyloid formation process in detail, in order to develop inhibitors to the process. At the DNA level, a point mutation segregating with HCCAA was identified in the cy
This thesis presents models and methods for feedback-based resource management for cyber-physical systems. Common for the scenarios considered are severe resource constraints, uncertain and time-varying conditions and the goal of enabling flexibility in systems design rather than restricting it. A brief survey on reservation-based scheduling, an important enabling technology for this thesis, is pr
The use of an intraoperative shunt is an established technique used to reduce the ischemic time after acute arterial obstruction or in the prevention of hypoperfusion due to complex open vascular or endovascular operative procedures. To date, described methods of temporary extremity blood perfusion have required open surgical techniques.
The Lorentzian lifetime widths of the 4d and 4f levels in the sixth-period elements W74 to Bi83 have been measured using photoelectron spectroscopy. A compilation of 4f-level widths from the literature is also made. The general trend of the 4f-level widths is well reproduced by McGuires calculations, although the absolute widths seem to be underestimated. The 4d5/2-level width shows a remarkable c
Java has proven to he a powerful language for software development. In this paper we show that it is also suitable for hardware compilation, making it an attractive language for embedded system development. Our compilation technique, which is presented here, is based on separating different aspects of the program and use dedicated and specialised optimisations and code generators for each aspect.
We have studied the formation of ohmic contacts to InAs nanowires by chemical etching and passivation of the contact areas in an ammonium polysulfide, (NH4)(2)S-x, water solution. The nanowires were exposed to different dilution levels of the (NH4)(2)Sx solution before contact metal evaporation. A process based on a highly diluted ( NH4)S-2(x) solution was found to be self-terminating, with minima
#073. adjusting to beams falling, for flute and violoncello (2006)
The Paris Climate Agreement defined an ambition of limiting global warming to 1.5 °C above preindustrial levels. This has triggered research on stringent emission reduction targets and corresponding mitigation pathways across energy economy and societal systems. Driven by methodological considerations, supply side and carbon dioxide removal options feature prominently in the emerging pathway liter
A measurement experiment regarding willingness to pay for antihypertensive therapy is reported. A new type of binary willingness to pay question is used, that allows for different degrees of certainty with respect to the responses. Mean willingness to pay is derived from a simple expected utility model and estimated using maximum likelihood methods. The estimated parameters are highly significant,
In this paper we present some ideas for knowledge representation formalism suitable for rational agents which learn how to choose the best conditional, partial plan in any given situation. In our architecture, the agent uses an incomplete symbolic inference engine, employing Active Logic, to reason about consequences of performing actions — including information-providing ones. It utilises a simpl
