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Cell death plays a pivotal role in many physiological processes, such as cell homeostasis, embryonic development, immune defence and in the pathophysiology of numerous diseases, such as cancer, infections and degenerative diseases. However, the lack of a comprehensive and up-to-date resource on cell death regulators poses a significant challenge to researchers in the field. Existing databases are of
Hepatocellular carcinoma (HCC) represents a major form of primary liver cancer in adults. Chronic infections with hepatitis B (HBV) and C (HCV) viruses and alcohol abuse are the major factors leading to HCC. This deadly cancer affects more than 500,000 people worldwide and it is quite resistant to conventional chemo- and radiotherapy. Genetic and epigenetic studies on HCC may help to understand be
Although the consequences of urbanization for the physiological health of animals are the focus of much active research, an overlooked aspect is how physiology could be indirectly modulated by the urban environment via changes in intraspecific behavioural interactions, particularly among gregarious species. Both urbanization and the establishment, as well as maintenance, of hierarchical rank posit
PurposeThe Physical Internet (PI) is an emerging concept that applies the Digital Internet as a design metaphor for the development of sustainable, interoperable and collaborative freight transport. With the aim of aiding researchers and policy makers in their future efforts to develop efficient logistics systems, the purpose of this paper is to present a review of the existing literature on the P
As a result of a scandal during the fall of 2017, where a famous producer was accused of having committed sex crimes, women who had been sexually harassed were asked to use #metoo in social medias with the purpose of highlighting the widespread occurrence of sexual harassment. The campaign grew into a modern popular movement, which in Sweden evolved into an appeal against sexual harassment at work
The favorable pharmacokinetics of MMC, used during intraperitoneal chemotherapy, has been reported in several studies [11-19]. A major safety issue in studies using intraperitoneal chemotherapy perfusion is the resulting systemic drug exposure. The AUCplasma is determined by the dose, the clearance, and the fraction absorbed from the peritoneal cavity. The reported mean plasma peak concentrations
Snapshot Spectral Imaging enables the acquisition of hyperspectral images (HSI) from 2D projected measurements employing specialized optical systems, such as the Coded Aperture Snapshot Spectral Imager (CASSI). Specifically, the CASSI system performs spatio-spectral codification of light obtaining 2D projected measurements. These measurements are then processed by algorithms to obtain the desired
Popular Science SummaryPolymers are giant molecules consisting of a repetition of many small units (monomers) that are linked together by chemical bonds. If we consider a long necklace as a polymer chain, the beads are the monomers and the part of the thread which connects the beads together is the chemical bond. Polymers are important materials in our everyday life and they can be found e.g., in This thesis incorporates studies on the aqueous systems of two types of thermoresponsive amphiphilic block copolymers; a series of nonionic triblock copolymers comprising blocks of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) denoted as PEO-PPO-PEO block copolymers, and a series of ionic diblock copolymers consisting of one charged block and one block of poly(N-isopropylacrylamide) (
To gain legitimacy for climate change adaptation decisions, the distribution of responsibility for these decisions and their implementation needs to be grounded in theories of just distribution and what those affected by decisions see as just. The purpose of this project is to contribute to sustainable spatial planning and the ability of local and regional public authorities to make well-informed
Spatial Data Infrastructure (SDI) development is widely known to be a challenging process owing to its complex and dynamic nature. Although great effort has been made to conceptually explain the complexity and dynamics of SDIs, few studies thus far have actually modeled these complexities. In fact, better modeling of SDI complexities will lead to more reliable plans for its development. A state-of
Syftet med uppsatsen är att undersöka förhållandet mellan yttrandefrihet och bestämmelsen om hets mot folkgrupp i svensk rätt, för att därefter jämföra hur rättsläget inom detta område ser ut i USA. Yttrandefrihetens förhållande till hets mot folkgrupp är något som har berörts i förarbeten till straffbestämmelsen, dock kvarstår det en viss problematik för när det ena intresset anses väga tyngre änThe main purpose of this thesis is to examine the relationship between freedom of speech and the regulation on a crime of racially motivated hate (in Sweden named hets mot folkgrupp found in Chapter 16 Section 8 of the Swedish Penal Code), thereafter in a comparison to the legal position of the issue in America. The foundation of the Swedish legislation of the crime is found in the Swedish Penal C
Calls to implement corporate reforms in South Korea reached its apex with the strong public outrage at 2016 Presidential corruption scandal involving the largest business groups within the country. In 2017, the newly elected President Moon Jae In promised to achieve corporate reforms that past administrations struggled to engage with. Considering the lack of progress in regulating unfair corporate
The space of open source supply chain attacks is ever evolving and growing. There is extensive previous work identifying and collecting open source supply chain attacks, as well as identifying patterns in these attacks and proving that machine learning models may be able to detect these patterns. The aim of this thesis is to develop such a system and study its efficacy in detecting attacks. To ac
Både i Sverige och utomlands finns det ett behov av tvistlösning som alternativ till domstolsprövning. I Sverige har sedan 1917 Stockholms Handelskammares Skiljedomsinstitut fungerat som institut för alternativ tvistlösning genom skiljeförfarande och en gångbar lagstiftning på området har i Sverige funnits sedan 1929. Skiljeförfarandet som tvistlösningssätt präglas av fyra essentiella hörnstenar -In Sweden as well as in other countries, there is a need for alternative dispute resolution as supposed to dispute resolution through a court of law. The Stockholm Chamber of Commerce has functioned as an institute for alternative dispute resolution by arbitration since 1917, whereas passable regulations on arbitration have been in force since 1929. The arbitration as a method of dispute resolutio
The purpose of this essay is to shed some light on the prehistory of a small area on the Danish island of Lolland. The location, called Klinteodde, is situated just off the coast on the northern part of the island. As a result of a quite extensive earth-work construction, a small peninsula has formed. On this peninsula, and in the sea surrounding it, a large quantity of knapped flint can be found.
The development of the European Union can be crucial for understanding possibilities for change in state sovereignty. Whether the European Union holds some characteristics that are otherwise incorporated in the notion of the state can be examined by looking at foreign policy, which is regarded as a central feature of sovereignty. The changing perceptions of European foreign policy by the European
Syftet med denna uppsats är att utifrån en rättsdogmatisk och en delvis rättssociologisk metod undersöka huruvida bedömningen av barnets bästa vid tvångsvård enligt 3 § LVU påverkas av barnets kön. Utifrån syftet följer frågeställningen: är det befogat att snarare tala om flickors och pojkars bästa, än det könsneutrala begreppet barnets bästa? LVU och möjligheten till tvångsvård av barn finns tiThe purpose of this thesis is to study whether the evaluation of the best interests of the child is affected by the child’s sex, on the occasion of compulsory care according to 3 § Care of Young Persons Act, LVU. The question that follows is: is it justified to use the best interests of boys and girls rather than the gender-neutral concept of the best interests of the child? LVU and the use of c
