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Accuracy of the quantification of organ activity from planar gamma camera images
The accuracy in determination of organ activity of Tc-99m was investigated, with activity estimated from gamma camera images of phantoms, using the, conjugate view method. The accuracy depends on several parameters such as the choice of background correction method, the accuracy in determination of the effective attenuation coefficient and the thickness of the body and organs and on the determinat
Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes
We have identified a new cyclic-nucleotide phosphodiesterase isoform, PDE3A, and cloned its cDNA from cultured aortic myocytes. The nucleotide sequence of its coding region is similar to that of the previously cloned myocardial isoform except for the absence of the initial 300-400 nt that are present in the latter, as confirmed by reverse-transcriptase-mediated PCR, 5' rapid amplification of cDNA
Lack of HIN-1 methylation in BRCAl-linked and "BRCA1-like" breast tumors
We recently identified a candidate tumor suppressor gene, HIN-1, that is silenced due to methylation in the majority of sporadic breast carcinomas and is localized to 5q33-qter, an area frequently lost in BRCA1 tumors and thought to harbor a BRCA1 modifier gene. To establish whether germ-line mutations in HIN-1 may influence breast cancer risk, we sequenced the HIN-1 coding region in 10 familial b
Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding
Thymidine kinase (TK) is the key enzyme in salvaging thymidine to produce thymidine monophosphate. Owing to its ability to phosphorylate nucleoside analogue prodrugs, TK has gained attention as a rate-limiting drug activator. We describe the structures of two bacterial TKs, one from the pathogen Bacillus anthracis in complex with the substrate dT, and the second from the food-poison-associated Bac
T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage.
BACKGROUND: T-wave alternans (TWA) is associated with prognosis after myocardial infarction (MI), however its link to the extent of ischemic injury has not been clarified. We analyzed the course of TWA and its relation to myocardial damage in experimental myocardial infarction. METHODS: In 21 pigs, infarction was induced by 40-minute long balloon inflation in LAD under continuous 12-lead ECG monit
A 0.55mW SAW-Less Receiver Front-End for Bluetooth Low Energy Applications
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https://www.lth.se/fileadmin/cee/Documents/STYR_2020_336_Fo__reskrifter.pdf - 2026-05-15
Growth of high-quality Ge epitaxial layers on Si(100)
A method of growing high-quality epitaxial Ge layers on a Si(100) substrate is reported. In this method, a 0.8 mum Si0.1Ge0.9 layer was first grown. Due to the large lattice mismatch between this layer and the Si substrate, many dislocations form near the interface and in the lower part of the Si0.1Ge0.9 layer. A 0.8 mum Si0.05Ge0.95 layer and a 1.0 mum top Ge layer were subsequently grown on the
A new subfamily of major intrinsic proteins in plants.
The major intrinsic proteins (MIPs) form a large protein family of ancient origin and are found in bacteria, fungi, animals, and plants. MIPs act as channels in membranes to facilitate passive transport across the membrane. Some MIPs allow small polar molecules like glycerol or urea to pass through the membrane. However, the majority of MIPs are thought to be aquaporins (AQPs), i.e., they are spec
Importance of protein S and phospholipid for activated protein C-mediated cleavages in factor Va.
The procoagulant function of activated factor V (FVa) is inhibited by activated protein C (APC) through proteolytic cleavages at Arg(306), Arg(506), and Arg(679). The effect of APC is potentiated by negatively charged phospholipid membranes and the APC cofactor protein S. Protein S has been reported to selectively stimulate cleavage at Arg(306), an effect hypothesized to be related to reorientatio
The accommodative pupil responses of children and young adults at low and intermediate levels of ambient illumination.
An excess of chromosome 1 breakpoints in male infertility.
In a search for potential infertility loci, which might be revealed by clustering of chromosomal breakpoints, we compiled 464 infertile males with a balanced rearrangement from Mendelian Cytogenetics Network database (MCNdb) and compared their karyotypes with those of a Danish nation-wide cohort. We excluded Robertsonian translocations, rearrangements involving sex chromosomes and common variants.
High Proportions of Proinflammatory Bacteria on the Colonic Mucosa in a Young Patient with Ulcerative Colitis as Revealed by Cloning and Sequencing of 16S rRNA Genes.
The pathogenesis of ulcerative colitis (UC) remains unknown. It is thought to be due to an abnormal and uncontrolled immune response to normally occurring constituents of the intestine. Microbial agents appear to be involved in the pathogenesis and intestinal bacteria seem to be an important factor in the development and chronicity. The aim of this study was to investigate the colonic microbiota o
Limited spread of penicillin-nonsusceptible pneumococci, Skane County, Sweden
In response to increasing frequencies of penicillin-non-susceptible pneumococci (PNSP), for which the MIC of penicillin was greater than or equal to0.12 mg/L, in Sk (a) over circle ne County, southern Sweden, national recommendations were initiated in 1995 to limit the spread of pneumococci with high MICs (greater than or equal to0.5 mg/L) of penicillin (PRP), especially among children of preschoo
Demographic transition of the Swedish cystic fibrosis community--results of modern care.
Assessing the results of modern cystic fibrosis (CF)-care and estimating the future population and its demography is important to evaluate the treatment regimens and to calculate the future needs of health-care resources.This paper updates previous incidence calculations. It assesses the results of modern CF-care in terms of survival and changing demography in Sweden. The incidence of CF in Sweden
Brian Burdekin Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law
Brian Burdekin Archives - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work M
https://rwi.lu.se/tag/brian-burdekin/ - 2026-05-15
Arbets- och miljömedicin utmanar ständigt – Vetenskap och Hälsa
Arbets- och miljömedicin utmanar ständigt – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Arbets- och miljömedicin utmanar ständigt 2012-02-22 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Det är lätt att tro att ett löst arbetsmiljöproblem är ett löst arb
https://www.vetenskaphalsa.se/arbets-och-miljomedicin-utmanar-standigt/ - 2026-05-15
Enkelt test för identifiering av havandeskaps-förgiftning på väg – Vetenskap och Hälsa
Enkelt test för identifiering av havandeskaps-förgiftning på väg – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Enkelt test för identifiering av havandeskaps-förgiftning på väg 2013-12-17 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Foto: Colourbox Ett a
https://www.vetenskaphalsa.se/enkelt-test-for-identifiering-av-havandeskaps-forgiftning-pa-vag/ - 2026-05-15
Epithelial cells purified from choroid plexus have receptors for vasoactive intestinal polypeptide
Using the choroid plexus from pig a method has been developed to purify the epithelial cells from the underlying vascularized connective tissue stroma. An epithelial cell fraction was obtained that showed a purity of at least 95%, as determined by light microscopic analysis. The epithelial cells were investigated for the presence of binding sites for the neurotransmitter peptide, vasoactive intest
