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BioMed CentralBMC Biotechnology ss Open AcceResearch article Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants Troels T Nielsen1,2, Johan Jakobsson1, Nina Rosenqvist1 and Cecilia Lundberg*1 Address: 1CNS Gene Therapy Unit, Wallenberg Neuroscience Center, Department of Experimental Medical Sciences, Lund University, BMC A11, S-221 84 Lund,
Department of Psychology Faculty of Social Sciences Lund University Handbook for the Doctoral Program Preface Doctoral programs are regulated at different levels - in the The Higher Education Ordinance, at the university level, at the faculty level, and locally at the institution. The purpose of this document is to provide an overview of the doctoral program at Department of Psychology. Both stude
https://www.psy.lu.se/sites/psy.lu.se/files/handbook_fu_engelska.pdf - 2026-05-18
A simple and novel method is presented to approximate by the lognormal distribution the probability density function of the sum of correlated lognormal random variables. The method is also shown to work well for approximating the distribution of the sum of lognormal-Rice or Suzuki random variables by the lognormal distribution. The method is based on matching a low-order Gauss-Hermite approximatio
Reception – hospitality and hostilityMarcus Knutagård and Arne KristiansenSchool of Social Work, Lund UniversityThe aim of this paper is to analyse the practice of reception of newly arrived migrants. The paper is part of an ongoing project Scanian homes: Reception, settlement or rejection – homelessness policies and strategies for refugee settlement. The aim of the project is to investigate the p
In recent decades, a ‘Haitian Turn’ has emerged as both academic and public readerships in the anglophone sphere have been flooded by a wave of essays, articles, and monographs on the Haitian Revolution (1791–1804). At the epicentre of the present study is one of the major interpretations of the Haitian Revolution in the Haitian Turn, which I call the ‘universality paradigm’. The universality paraIn recent decades, a ‘Haitian Turn’ has emerged as both academic and public readerships in the anglophone sphere have been flooded by a wave of essays, articles, and monographs on the Haitian Revolution (1791–1804). At the epicentre of the present study is one of the major interpretations of the Haitian Revolution in the Haitian Turn, which I call the ‘universality paradigm’. The universality para
Just as the title above suggests, it is difficult to address health issues without considering the role of the media and everyday life; the time and space when health is produced and cared for or put at risk and exposed. In the introduction to this special issue, ‘Media and health in everyday life’, we will discuss the three components of the theme. We will offer some definitions, but also problem
This paper has two purposes. The first purpose is methodological and aims to extend previous work on efficiency analysis by implementing a multiple-output stochastic ray frontier production function model. This model generalizes the single-output stochastic frontier model to multiple-input, multiple-output technologies and allows simultaneous estimation of technical efficiency and analysis of infl
Ligand exchange at square-planar [Pd(MeCN)4]2+ and [Pd(EtCN)4]2+ has been studied by 1H NMR line broadening and at [Pt(MeCN)4]2+ and [Pt(EtCN)4]2+ by isotopic labelling using 1H NMR spectroscopy in deuteriated nitromethane. Exchange takes place via two-term rate laws Rex/4 = (k1 + k2[RCN])cM with well defined k1 paths. Rate constants per co-ordination site k1298/s–1, k2298/kg mol–1 s–1 are 6.9 ± 1Ligand exchange at square-planar [Pd(MeCN)4]2+ and [Pd(EtCN)4]2+ has been studied by 1H NMR line broadening and at [Pt(MeCN)4]2+ and [Pt(EtCN)4]2+ by isotopic labelling using 1H NMR spectroscopy in deuteriated nitromethane. Exchange takes place via two-term rate laws Rex/4 = (k1 + k2[RCN])cM with well defined k1 paths. Rate constants per co-ordination site k1298/s–1, k2298/kg mol–1 s–1 are 6.9 ± 1
To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel
This article explores four preselected permanent magnet synchronous machine (PMSM) topologies suitable for direct mounting on low pressure spool in a turbo fan engine. The challenge of contributing to More Electric Engine (MEE) development is that the electrical machine needs to operate over wide speed range, take advantage of available space that forces to use a high number of poles and last but
The fragmentation functions of quarks and gluons are measured in various three-jet topologies in Z decays from the full data set collected with the DELPHI detector at the Z resonance between 1992 and 995. The results at different values of transverse momentum-like scales are compared. A parameterization of the quark and gluon fragmentation functions at a fixed reference scale is given. The quark a
A search for a heavy neutral Higgs boson, A, decaying into a Z boson and another heavy Higgs boson, H, is performed using a data sample corresponding to an integrated luminosity of 36.1 fb−1 from proton–proton collisions at s=13 TeV recorded in 2015 and 2016 by the ATLAS detector at the Large Hadron Collider. The search considers the Z boson decaying to electrons or muons and the H boson into a pa
Why are some states more corrupt than others? Drawing on the literature on governance in parliamentary democracies, we suggest that the degree of corruption depends on the ability of key political actors to control ministers who have been delegated power. We argue that the Prime Minister has incentives to limit corruption within the cabinet and has the ability to do so when there are certain “cont
In phase-change memory devices, a material is cycled between glassy and crystalline states. The highly temperature-dependent kinetics of its crystallization process enables application in memory technology, but the transition has not been resolved on an atomic scale. Using femtosecond x-ray diffraction and ab initio computer simulations, we determined the time-dependent pair-correlation function o
Serine hydroxymethyltransferase (SHMT) is the major source of 1-carbon units required for nucleotide synthesis. Humans have cytosolic (SHMT1) and mitochondrial (SHMT2) isoforms, which are upregulated in numerous cancers, making the enzyme an attractive drug target. Here, we show that the antifolates lometrexol and pemetrexed are inhibitors of SHMT2 and solve the first SHMT2-antifolate structures.
The haptoglobin phenotypes of Sudanese patients with complicated and uncomplicated falciparum malaria, and those of uninfected randomly selected individuals, were determined by electrophoresis of sera on polyacrylamide gels followed by benzidine staining of the gels. Among 273 malaria patients, the proportions with haptoglobin phenotypes (1-1), (2-1) and (2-2) were 60.8%, 29.7% and 9.5%, respectiv
