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Pre- and post-test probabilities of venous thromboembolism and diagnostic accuracy of D-dimer, estimated by European clinicians working in emergency departments

In patients with suspected venous thromboembolism (VTE), it is recommended to estimate the pre-test probability of VTE, either by experience or by standardized scoring schemes (e.g. Wells or Geneva score), before performing a D-dimer test [1], [2]. Patients with a low probability or unlikely VTE should have D-dimer performed, and if negative, VTE can be excluded, without further investigations, wh

The impact of myocardial fibrosis biomarkers in a heart failure population with atrial fibrillation—The HARVEST-Malmö study

Background: Several studies suggest that circulating biomarkers of myocardial fibrosis are associated with worse prognosis in subjects with atrial fibrillation (AF). Here, we aimed to explore associations between fibrosis biomarkers, prevalent AF, and left atrial volume (LAV) enlargement in subjects with heart failure (HF). Additionally, we evaluated the prognostic impact of fibrotic biomarkers in

How do we and how should we deal with uncertainty in endodontics

In many clinical cases a dentist may feel certain when for example diagnosing, deciding on treatment, or assessing the prognosis—in other cases many dentists may feel a degree of doubt or uncertainty. This paper aims to explore the philosophical concept of uncertainty and its different dimensions, using the condition “persistent apical periodontitis associated with a previously root filled tooth”

Zero waste for all? : Sustainable practices in a small-scale zero waste community from a universal design perspective

Since 2003, Kamikatsu in Japan has established a sustainable zero-waste practice that has achieved a recycling rate exceeding 80%. By exploring how the community has shaped itself around the zero-waste concept, this paper aims to enhance our understanding of zero waste in practice from a universal design perspective. Interviews and photo documentation were used to gather data. The zero-waste conceSince 2003, Kamikatsu in Japan has established a sustainable zero-waste practice that has achieved a recycling rate exceeding 80%. By exploring how the community has shaped itself around the zero-waste concept, this paper aims to enhance our understanding of zero waste in practice from a universal design perspective. Interviews and photo documentation were used to gather data. The zero-waste conce

Added sugar intake and its associations with incidence of seven different cardiovascular diseases in 69,705 Swedish men and women

Introduction: The adverse health effects of sugar-sweetened beverage intake are well-established, but the implications of overall added sugar intake remain unclear. We investigated the associations between intake of added sugar and various sugar-sweetened foods and beverages and risk of 7 cardiovascular diseases in 69,705 participants aged 45–83 years (47.2% female) from the Swedish Mammography co

The Gaia -ESO survey: Mixing processes in low-mass stars traced by lithium abundance in cluster and field stars

Aims. We aim to constrain the mixing processes in low-mass stars by investigating the behaviour of the Li surface abundance after the main sequence. We take advantage of the data from the sixth internal data release of Gaia-ESO, IDR6, and from the Gaia Early Data Release 3, EDR3s. Methods. We selected a sample of main-sequence, sub-giant, and giant stars in which the Li abundance is measured by th

Regulation of lipoprotein lipase. Induction by insulin

Lipoprotein lipase activity in intact epididymal adipose tissue of fasted rats increased rapidly after treatment with insulin in vivo. In contrast, lipoprotein lipase activity in adipocytes isolated from the contralateral fat pads remained essentially unchanged. When adipocytes were incubated for 30 min at ambient temperature in vitro, about 2 times more lipoprotein lipase activity was found in th

Eating difficulties in elderly, focusing on patients with stroke.

Popular Abstract in Swedish För att ge en god omvårdnad behövs kunskaper om ätproblem som helhet och om möjliga hinder för optimalt näringsintag hos äldre patienter, särskilt de med stroke. Sådana kunskaper behövs eftersom åldrandet i sig självt eller tillsammans med sjukdom, t.ex. stroke och dess följder, kan påverka förmågan att äta och därmed också näringsintaget med ökad risk för såväl undernäThe aim of this thesis was to describe eating difficulties and interventions to improve eating among elderly patients, especially those with stroke, to make comparisons between patients with dysphagia and those without (Papers I & II), those with and without assisted eating (Paper IV), and to analyse the relation between eating difficulties, nutritional status (Papers II-V), pressure ulcers (P

A fast correlation attack on LILI-128

In this paper we demonstrate a fast correlation attack on the recently proposed stream cipher LILI-128. The attack has complexity around 2(71) bit operations assuming a received sequence of length around 2(30) bits and a precomputation phase of complexity 2(79) table lookups. This complexity is significantly lower than 2(112), which was conjectured by the inventors of LILI-128 to be a lower bound

Economic Analyses of Drinking Water and Sanitation in Developing Countries

Popular Abstract in Swedish Denna avhandling fokuserar på två av de många faktorer som är av fundamental betydelse både för människors välfärd och för ett lands utveckling dvs. val av dricksvattenkälla och toalettfacilitet. I avhandlingen analyseras olika aspekter av hushållsefterfrågan på dessa två faktorer med hjälp av data från Filippinerna och Bangladesh. Avhandlingen består av fem kapitel, etThis thesis focuses on different aspects of household demand, and the determinants of demand, for water and sanitation related inputs fundamental to the households' well-being, i.e. drinking water and toilet facilities. The thesis consists of five chapters, one introductory chapter and four self-contained, essentially empirical, studies. In chapter two, Women's Health Choices and the Effects on C

The EGF-like Modules of Anticoagulant Protein S. Studies of Ca2+ binding and module interactions

Popular Abstract in Swedish I samband med en kärlskada startar en kaskad av reaktioner som leder fram till bildandet av ett blodkoagel. Det är viktigt att bildandet av blodkoagel begränsas till det skadade området. Blodkoagulationen är därför reglerad av antal antikoagulanta system av vilka det viktigaste är protein C systemet. I detta system samverkar aktivt protein C (APC) tillsammans med ett anProtein S functions as a cofactor to activated protein C (APC) in the degradation of factors Va and VIIIa. In plasma protein S circulates in two forms; 30-40 % circulates as free protein S molecules while the remaining 60-70 % exists in a 1:1 complex with C4b-binding protein (C4BP). Only the free form of protein S functions as a cofactor to APC. Protein S is a mosaic protein composed of four discr

Usage statistics and usage patterns on the NorduGrid: Analyzing the logging information collected on one of the largest production Grids of the world

The Nordic Grid facility (NorduGrid [1]) came into operation during summer 2002 when the Scandinavian ATLAS HEP group started to use the Grid for the ATLAS Data Challenges (DC) and was thus the first Grid ever contributing to an ATLAS production. Since then, the Grid facility has been in continuous 24/7 operation. NorduGrid is being used by a growing set of active users from various scientific are

The Problem of Partial Migration - the Case of the Blue Tit

In the evolution of bird migration, partial migration is assumed to be an important intermediate step between migration and residency. Partial migration is characterised by the existence of both migratory and resident individuals in a given population. Compared to regular migration, relatively little is known about partial migrants and their migratory performances. In my thesis, I have studied th

In vitro contractile responses of detrusor to carbachol and neurokinin A, in children with recurrent urinary tract infection or day wetting

OBJECTIVE: To investigate whether a history of recurrent urinary tract infection (UTI) and/or the presence of day-wetting/urge symptoms might influence the contractile responses to the cholinergic agonist carbachol or to the sensory neuropeptide neurokinin A (NKA) in the urinary bladder in children. PATIENTS AND METHODS: Small detrusor strips were taken from the margin of the cystotomy incision of

Coarse-grained molecular dynamics investigation of nanostructures and thermal properties of porous anode for solid oxide fuel cell

Incorporation of nanoscale catalysts into porous structures of SOFC has been proven highly successful in increasing active sites and catalyst utilization. In addition, electrochemical reactions as well as heat transfer process in porous anode are strongly affected by complex porous structures. It is believed that study of anode thermal properties are critical for SOFC design and operation. In this

Laparoscopic Roux-en-Y gastric bypass in adolescents with morbid obesity-Surgical aspects and clinical outcome.

In this paper, we address surgical aspects on bariatric surgery in adolescents from a nationwide Swedish study. Laparoscopic gastric bypass surgery was performed for 81 adolescents with morbid obesity (13-18 years), while 81 adolescents with obesity-matched by age, sex, and BMI received conventional care. Another comparison group was adults undergoing gastric bypass at the same institution during

Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma

Frequent loss of heterozygosity in head and neck squamous cell carcinoma (HNSCC) has been found in several chromosomal regions such as 3p, 9p, 11q, 13q and 17p. Fragile histidine triad (FHIT) gene is located at 3p14.2 encompassing a common fragile site, and is identified as a tumor suppressor gene. We examined 57 patients with HNSCC using immunohistochemistry, western blot, and reverse transcripta

Estimation of Short-Term Effects of Air Pollution on Stroke Hospital Admissions in Southern Sweden.

Background: Short-term exposure to high levels of air pollution can increase stroke risk. In this study we investigated the short-term effects of air pollution on hospital admissions for stroke in a setting where pollutant levels are rather low. We also addressed methodological issues in evaluating the short-term effects of air pollution. Methods: Daily admissions of ischemic (n = 11,267) and hemo

Geomechanical simulation to predict open subsurface fractures

Geomechanical simulation of the evolution of a geological structure can play an important role in predicting open fracture development for all stages in that structure's development. In this work, three such geomechanical simulations are used to predict the evolving stress and strain fields, including dilational and compactional changes in the rock fabric in developing fault and fold systems. Thei